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MGRN1 (mahogunin ring finger 1)

Identity

Alias_namesmahogunin, ring finger 1
mahogunin ring finger 1, E3 ubiquitin protein ligase
Alias_symbol (synonym)KIAA0544
RNF156
Other alias
HGNC (Hugo) MGRN1
LocusID (NCBI) 23295
Atlas_Id 68970
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 4624824 and ends at 4690974 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
APOBEC3C (22q13.1) / MGRN1 (16p13.3)ESCO1 (18q11.2) / MGRN1 (16p13.3)MGRN1 (16p13.3) / CRIM1 (2p22.3)
MGRN1 (16p13.3) / LINC00235 (16p13.3)MGRN1 (16p13.3) / PXN (12q24.23)MGRN1 (16p13.3) / SNX29 (16p13.13)
MLYCD (16q23.3) / MGRN1 (16p13.3)UBN1 (16p13.3) / MGRN1 (16p13.3)UBN1 MGRN1
MLYCD MGRN1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MGRN1   20254
Cards
Entrez_Gene (NCBI)MGRN1  23295  mahogunin ring finger 1
AliasesRNF156
GeneCards (Weizmann)MGRN1
Ensembl hg19 (Hinxton)ENSG00000102858 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102858 [Gene_View]  chr16:4624824-4690974 [Contig_View]  MGRN1 [Vega]
ICGC DataPortalENSG00000102858
TCGA cBioPortalMGRN1
AceView (NCBI)MGRN1
Genatlas (Paris)MGRN1
WikiGenes23295
SOURCE (Princeton)MGRN1
Genetics Home Reference (NIH)MGRN1
Genomic and cartography
GoldenPath hg38 (UCSC)MGRN1  -     chr16:4624824-4690974 +  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MGRN1  -     16p13.3   [Description]    (hg19-Feb_2009)
EnsemblMGRN1 - 16p13.3 [CytoView hg19]  MGRN1 - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBIMGRN1 [Mapview hg19]  MGRN1 [Mapview hg38]
OMIM607559   
Gene and transcription
Genbank (Entrez)AB011116 AK299052 BC007627 BC014199 BC050389
RefSeq transcript (Entrez)NM_001142289 NM_001142290 NM_001142291 NM_015246
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MGRN1
Cluster EST : UnigeneHs.526494 [ NCBI ]
CGAP (NCI)Hs.526494
Alternative Splicing GalleryENSG00000102858
Gene ExpressionMGRN1 [ NCBI-GEO ]   MGRN1 [ EBI - ARRAY_EXPRESS ]   MGRN1 [ SEEK ]   MGRN1 [ MEM ]
Gene Expression Viewer (FireBrowse)MGRN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23295
GTEX Portal (Tissue expression)MGRN1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60291   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60291  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60291
Splice isoforms : SwissVarO60291
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusO60291
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)MGRN1
DMDM Disease mutations23295
Blocks (Seattle)MGRN1
SuperfamilyO60291
Human Protein AtlasENSG00000102858
Peptide AtlasO60291
HPRD07397
IPIIPI00643212   IPI00297251   IPI00915351   IPI01013740   IPI00915359   
Protein Interaction databases
DIP (DOE-UCLA)O60291
IntAct (EBI)O60291
FunCoupENSG00000102858
BioGRIDMGRN1
STRING (EMBL)MGRN1
ZODIACMGRN1
Ontologies - Pathways
QuickGOO60291
Ontology : AmiGOprotein polyubiquitination  ubiquitin-protein transferase activity  protein binding  nucleus  cytoplasm  early endosome  cytosol  plasma membrane  protein monoubiquitination  zinc ion binding  endosome to lysosome transport  membrane  negative regulation of cAMP-mediated signaling  negative regulation of G-protein coupled receptor protein signaling pathway  ubiquitin protein ligase activity  extracellular exosome  
Ontology : EGO-EBIprotein polyubiquitination  ubiquitin-protein transferase activity  protein binding  nucleus  cytoplasm  early endosome  cytosol  plasma membrane  protein monoubiquitination  zinc ion binding  endosome to lysosome transport  membrane  negative regulation of cAMP-mediated signaling  negative regulation of G-protein coupled receptor protein signaling pathway  ubiquitin protein ligase activity  extracellular exosome  
Pathways : KEGGUbiquitin mediated proteolysis   
NDEx NetworkMGRN1
Atlas of Cancer Signalling NetworkMGRN1
Wikipedia pathwaysMGRN1
Orthology - Evolution
OrthoDB23295
GeneTree (enSembl)ENSG00000102858
Phylogenetic Trees/Animal Genes : TreeFamMGRN1
HOVERGENO60291
HOGENOMO60291
Homologs : HomoloGeneMGRN1
Homology/Alignments : Family Browser (UCSC)MGRN1
Gene fusions - Rearrangements
Fusion: TCGAUBN1 MGRN1
Fusion: TCGAMLYCD MGRN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMGRN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MGRN1
dbVarMGRN1
ClinVarMGRN1
1000_GenomesMGRN1 
Exome Variant ServerMGRN1
ExAC (Exome Aggregation Consortium)MGRN1 (select the gene name)
Genetic variants : HAPMAP23295
Genomic Variants (DGV)MGRN1 [DGVbeta]
DECIPHERMGRN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMGRN1 
Mutations
ICGC Data PortalMGRN1 
TCGA Data PortalMGRN1 
Broad Tumor PortalMGRN1
OASIS PortalMGRN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMGRN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMGRN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MGRN1
DgiDB (Drug Gene Interaction Database)MGRN1
DoCM (Curated mutations)MGRN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MGRN1 (select a term)
intoGenMGRN1
Cancer3DMGRN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607559   
Orphanet
MedgenMGRN1
Genetic Testing Registry MGRN1
NextProtO60291 [Medical]
TSGene23295
GENETestsMGRN1
Target ValidationMGRN1
Huge Navigator MGRN1 [HugePedia]
snp3D : Map Gene to Disease23295
BioCentury BCIQMGRN1
ClinGenMGRN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23295
Chemical/Pharm GKB GenePA134941221
Clinical trialMGRN1
Miscellaneous
canSAR (ICR)MGRN1 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMGRN1
EVEXMGRN1
GoPubMedMGRN1
iHOPMGRN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:27:22 CEST 2017

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