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MIA3 (MIA SH3 domain ER export factor 3)

Identity

Alias_namesmelanoma inhibitory activity family member 3
Alias_symbol (synonym)UNQ6077
FLJ39207
KIAA0268
TANGO
TANGO1
Other aliasARNT
D320
HGNC (Hugo) MIA3
LocusID (NCBI) 375056
Atlas_Id 43090
Location 1q41  [Link to chromosome band 1q41]
Location_base_pair Starts at 222618102 and ends at 222668012 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MBD5 (2q23.1) / MIA3 (1q41)MIA3 (1q41) / NUP98 (11p15.4)MIA3 (1q41) / PABPC1L (20q13.12)
MIA3 (1q41) / SLAIN1 (13q22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MIA3   24008
Cards
Entrez_Gene (NCBI)MIA3  375056  MIA SH3 domain ER export factor 3
AliasesARNT; D320; TANGO; TANGO1; 
UNQ6077
GeneCards (Weizmann)MIA3
Ensembl hg19 (Hinxton)ENSG00000154305 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000154305 [Gene_View]  ENSG00000154305 [Sequence]  chr1:222618102-222668012 [Contig_View]  MIA3 [Vega]
ICGC DataPortalENSG00000154305
TCGA cBioPortalMIA3
AceView (NCBI)MIA3
Genatlas (Paris)MIA3
WikiGenes375056
SOURCE (Princeton)MIA3
Genetics Home Reference (NIH)MIA3
Genomic and cartography
GoldenPath hg38 (UCSC)MIA3  -     chr1:222618102-222668012 +  1q41   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MIA3  -     1q41   [Description]    (hg19-Feb_2009)
EnsemblMIA3 - 1q41 [CytoView hg19]  MIA3 - 1q41 [CytoView hg38]
Mapping of homologs : NCBIMIA3 [Mapview hg19]  MIA3 [Mapview hg38]
OMIM613455   
Gene and transcription
Genbank (Entrez)AK025122 AK025506 AK026489 AK096526 AK290335
RefSeq transcript (Entrez)NM_001300867 NM_001324062 NM_001324063 NM_001324064 NM_001324065 NM_198551
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MIA3
Cluster EST : UnigeneHs.118474 [ NCBI ]
CGAP (NCI)Hs.118474
Alternative Splicing GalleryENSG00000154305
Gene ExpressionMIA3 [ NCBI-GEO ]   MIA3 [ EBI - ARRAY_EXPRESS ]   MIA3 [ SEEK ]   MIA3 [ MEM ]
Gene Expression Viewer (FireBrowse)MIA3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)375056
GTEX Portal (Tissue expression)MIA3
Human Protein AtlasENSG00000154305-MIA3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5JRA6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5JRA6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5JRA6
Splice isoforms : SwissVarQ5JRA6
PhosPhoSitePlusQ5JRA6
Domaine pattern : Prosite (Expaxy)SH3 (PS50002)   
Domains : Interpro (EBI)SH3-like_dom_sf    SH3_domain   
Domain families : Pfam (Sanger)SH3_2 (PF07653)   
Domain families : Pfam (NCBI)pfam07653   
Conserved Domain (NCBI)MIA3
DMDM Disease mutations375056
Blocks (Seattle)MIA3
PDB (SRS)5KYN    5KYU    5KYW   
PDB (PDBSum)5KYN    5KYU    5KYW   
PDB (IMB)5KYN    5KYU    5KYW   
PDB (RSDB)5KYN    5KYU    5KYW   
Structural Biology KnowledgeBase5KYN    5KYU    5KYW   
SCOP (Structural Classification of Proteins)5KYN    5KYU    5KYW   
CATH (Classification of proteins structures)5KYN    5KYU    5KYW   
SuperfamilyQ5JRA6
Human Protein Atlas [tissue]ENSG00000154305-MIA3 [tissue]
Peptide AtlasQ5JRA6
IPIIPI00455473   IPI00739902   IPI00741107   IPI00655578   IPI01010123   IPI00718836   
Protein Interaction databases
DIP (DOE-UCLA)Q5JRA6
IntAct (EBI)Q5JRA6
FunCoupENSG00000154305
BioGRIDMIA3
STRING (EMBL)MIA3
ZODIACMIA3
Ontologies - Pathways
QuickGOQ5JRA6
Ontology : AmiGOGolgi membrane  cell migration involved in sprouting angiogenesis  positive regulation of leukocyte migration  protein binding  endoplasmic reticulum lumen  endoplasmic reticulum membrane  endoplasmic reticulum membrane  endoplasmic reticulum membrane  exocytosis  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  negative regulation of cell adhesion  protein secretion  protein transport  membrane  integral component of membrane  negative regulation of cell migration  cargo loading into vesicle  wound healing  lipoprotein transport  lipoprotein transporter activity  lipoprotein transporter activity  intracellular membrane-bounded organelle  post-translational protein modification  cellular protein metabolic process  endoplasmic reticulum exit site  endoplasmic reticulum exit site  cargo loading into COPII-coated vesicle  cellular response to oxidised low-density lipoprotein particle stimulus  negative regulation of leukocyte cell-cell adhesion  negative regulation of lymphocyte migration  
Ontology : EGO-EBIGolgi membrane  cell migration involved in sprouting angiogenesis  positive regulation of leukocyte migration  protein binding  endoplasmic reticulum lumen  endoplasmic reticulum membrane  endoplasmic reticulum membrane  endoplasmic reticulum membrane  exocytosis  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  negative regulation of cell adhesion  protein secretion  protein transport  membrane  integral component of membrane  negative regulation of cell migration  cargo loading into vesicle  wound healing  lipoprotein transport  lipoprotein transporter activity  lipoprotein transporter activity  intracellular membrane-bounded organelle  post-translational protein modification  cellular protein metabolic process  endoplasmic reticulum exit site  endoplasmic reticulum exit site  cargo loading into COPII-coated vesicle  cellular response to oxidised low-density lipoprotein particle stimulus  negative regulation of leukocyte cell-cell adhesion  negative regulation of lymphocyte migration  
NDEx NetworkMIA3
Atlas of Cancer Signalling NetworkMIA3
Wikipedia pathwaysMIA3
Orthology - Evolution
OrthoDB375056
GeneTree (enSembl)ENSG00000154305
Phylogenetic Trees/Animal Genes : TreeFamMIA3
HOVERGENQ5JRA6
HOGENOMQ5JRA6
Homologs : HomoloGeneMIA3
Homology/Alignments : Family Browser (UCSC)MIA3
Gene fusions - Rearrangements
Fusion : QuiverMIA3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMIA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MIA3
dbVarMIA3
ClinVarMIA3
1000_GenomesMIA3 
Exome Variant ServerMIA3
ExAC (Exome Aggregation Consortium)ENSG00000154305
GNOMAD BrowserENSG00000154305
Varsome BrowserMIA3
Genetic variants : HAPMAP375056
Genomic Variants (DGV)MIA3 [DGVbeta]
DECIPHERMIA3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMIA3 
Mutations
ICGC Data PortalMIA3 
TCGA Data PortalMIA3 
Broad Tumor PortalMIA3
OASIS PortalMIA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMIA3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMIA3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MIA3
DgiDB (Drug Gene Interaction Database)MIA3
DoCM (Curated mutations)MIA3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MIA3 (select a term)
intoGenMIA3
Cancer3DMIA3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613455   
Orphanet
DisGeNETMIA3
MedgenMIA3
Genetic Testing Registry MIA3
NextProtQ5JRA6 [Medical]
TSGene375056
GENETestsMIA3
Target ValidationMIA3
Huge Navigator MIA3 [HugePedia]
snp3D : Map Gene to Disease375056
BioCentury BCIQMIA3
ClinGenMIA3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD375056
Chemical/Pharm GKB GenePA143485536
Clinical trialMIA3
Miscellaneous
canSAR (ICR)MIA3 (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMIA3
EVEXMIA3
GoPubMedMIA3
iHOPMIA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:19:57 CET 2018

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