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MIB1 (mindbomb E3 ubiquitin protein ligase 1)

Identity

Alias_namesmindbomb homolog 1 (Drosophila)
Alias_symbol (synonym)DIP-1
MIB
KIAA1323
ZZANK2
ZZZ6
Other aliasDIP1
LVNC7
HGNC (Hugo) MIB1
LocusID (NCBI) 57534
Atlas_Id 50133
Location 18q11.2  [Link to chromosome band 18q11]
Location_base_pair Starts at 21741329 and ends at 21870957 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MIB1 (18q11.2) / MIB1 (18q11.2)PCDH7 (4p15.1) / MIB1 (18q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MIB1   21086
LRG (Locus Reference Genomic)LRG_759
Cards
Entrez_Gene (NCBI)MIB1  57534  mindbomb E3 ubiquitin protein ligase 1
AliasesDIP-1; DIP1; LVNC7; MIB; 
ZZANK2; ZZZ6
GeneCards (Weizmann)MIB1
Ensembl hg19 (Hinxton)ENSG00000101752 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101752 [Gene_View]  chr18:21741329-21870957 [Contig_View]  MIB1 [Vega]
ICGC DataPortalENSG00000101752
TCGA cBioPortalMIB1
AceView (NCBI)MIB1
Genatlas (Paris)MIB1
WikiGenes57534
SOURCE (Princeton)MIB1
Genetics Home Reference (NIH)MIB1
Genomic and cartography
GoldenPath hg38 (UCSC)MIB1  -     chr18:21741329-21870957 +  18q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MIB1  -     18q11.2   [Description]    (hg19-Feb_2009)
EnsemblMIB1 - 18q11.2 [CytoView hg19]  MIB1 - 18q11.2 [CytoView hg38]
Mapping of homologs : NCBIMIB1 [Mapview hg19]  MIB1 [Mapview hg38]
OMIM608677   615092   
Gene and transcription
Genbank (Entrez)AB037744 AK027338 AK075157 AK091266 AL713705
RefSeq transcript (Entrez)NM_020774
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MIB1
Cluster EST : UnigeneHs.140903 [ NCBI ]
CGAP (NCI)Hs.140903
Alternative Splicing GalleryENSG00000101752
Gene ExpressionMIB1 [ NCBI-GEO ]   MIB1 [ EBI - ARRAY_EXPRESS ]   MIB1 [ SEEK ]   MIB1 [ MEM ]
Gene Expression Viewer (FireBrowse)MIB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57534
GTEX Portal (Tissue expression)MIB1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86YT6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86YT6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86YT6
Splice isoforms : SwissVarQ86YT6
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ86YT6
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)    MIB_HERC2 (PS51416)    ZF_RING_2 (PS50089)    ZF_ZZ_1 (PS01357)    ZF_ZZ_2 (PS50135)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    Mib_Herc2    Znf_RING    Znf_RING/FYVE/PHD    Znf_ZZ   
Domain families : Pfam (Sanger)Ank_2 (PF12796)    MIB_HERC2 (PF06701)    ZZ (PF00569)   
Domain families : Pfam (NCBI)pfam12796    pfam06701    pfam00569   
Domain families : Smart (EMBL)ANK (SM00248)  RING (SM00184)  ZnF_ZZ (SM00291)  
Conserved Domain (NCBI)MIB1
DMDM Disease mutations57534
Blocks (Seattle)MIB1
PDB (SRS)4TSE    4XI6    4XI7    4XIB   
PDB (PDBSum)4TSE    4XI6    4XI7    4XIB   
PDB (IMB)4TSE    4XI6    4XI7    4XIB   
PDB (RSDB)4TSE    4XI6    4XI7    4XIB   
Structural Biology KnowledgeBase4TSE    4XI6    4XI7    4XIB   
SCOP (Structural Classification of Proteins)4TSE    4XI6    4XI7    4XIB   
CATH (Classification of proteins structures)4TSE    4XI6    4XI7    4XIB   
SuperfamilyQ86YT6
Human Protein AtlasENSG00000101752
Peptide AtlasQ86YT6
HPRD06660
IPIIPI00183054   
Protein Interaction databases
DIP (DOE-UCLA)Q86YT6
IntAct (EBI)Q86YT6
FunCoupENSG00000101752
BioGRIDMIB1
STRING (EMBL)MIB1
ZODIACMIB1
Ontologies - Pathways
QuickGOQ86YT6
Ontology : AmiGOblood vessel development  in utero embryonic development  somitogenesis  neural tube formation  heart looping  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  cytoplasm  centrosome  cytosol  plasma membrane  endocytosis  Notch signaling pathway  zinc ion binding  postsynaptic density  protein ubiquitination  cytoplasmic vesicle  negative regulation of neuron differentiation  positive regulation of endocytosis  
Ontology : EGO-EBIblood vessel development  in utero embryonic development  somitogenesis  neural tube formation  heart looping  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  cytoplasm  centrosome  cytosol  plasma membrane  endocytosis  Notch signaling pathway  zinc ion binding  postsynaptic density  protein ubiquitination  cytoplasmic vesicle  negative regulation of neuron differentiation  positive regulation of endocytosis  
NDEx NetworkMIB1
Atlas of Cancer Signalling NetworkMIB1
Wikipedia pathwaysMIB1
Orthology - Evolution
OrthoDB57534
GeneTree (enSembl)ENSG00000101752
Phylogenetic Trees/Animal Genes : TreeFamMIB1
HOVERGENQ86YT6
HOGENOMQ86YT6
Homologs : HomoloGeneMIB1
Homology/Alignments : Family Browser (UCSC)MIB1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMIB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MIB1
dbVarMIB1
ClinVarMIB1
1000_GenomesMIB1 
Exome Variant ServerMIB1
ExAC (Exome Aggregation Consortium)MIB1 (select the gene name)
Genetic variants : HAPMAP57534
Genomic Variants (DGV)MIB1 [DGVbeta]
DECIPHERMIB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMIB1 
Mutations
ICGC Data PortalMIB1 
TCGA Data PortalMIB1 
Broad Tumor PortalMIB1
OASIS PortalMIB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMIB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMIB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MIB1
DgiDB (Drug Gene Interaction Database)MIB1
DoCM (Curated mutations)MIB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MIB1 (select a term)
intoGenMIB1
Cancer3DMIB1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608677    615092   
Orphanet10750   
MedgenMIB1
Genetic Testing Registry MIB1
NextProtQ86YT6 [Medical]
TSGene57534
GENETestsMIB1
Target ValidationMIB1
Huge Navigator MIB1 [HugePedia]
snp3D : Map Gene to Disease57534
BioCentury BCIQMIB1
ClinGenMIB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57534
Chemical/Pharm GKB GenePA134862722
Clinical trialMIB1
Miscellaneous
canSAR (ICR)MIB1 (select the gene name)
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMIB1
EVEXMIB1
GoPubMedMIB1
iHOPMIB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Wed Jun 7 12:43:00 CEST 2017

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