Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MICAL3 (microtubule associated monooxygenase, calponin and LIM domain containing 3)

Identity

Alias (NCBI)MICAL-3
HGNC (Hugo) MICAL3
HGNC Alias symbKIAA0819
LocusID (NCBI) 57553
Atlas_Id 56227
Location 22q11.21  [Link to chromosome band 22q11]
Location_base_pair Starts at 17787650 and ends at 18024561 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ERBB3 (12q13.2) / MICAL3 (22q11.21)HIST2H2BF (1q21.2) / MICAL3 (22q11.21)MICAL3 (22q11.21) / MICAL3 (22q11.21)
MICAL3 (22q11.21) / PPT1 (1p34.2)MICAL3 (22q11.21) / SLC1A3 (5p13.2)MICAL3 (22q11.21) / SLC25A18 (22q11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)MICAL3   24694
Cards
Entrez_Gene (NCBI)MICAL3    microtubule associated monooxygenase, calponin and LIM domain containing 3
AliasesMICAL-3
GeneCards (Weizmann)MICAL3
Ensembl hg19 (Hinxton)ENSG00000243156 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000243156 [Gene_View]  ENSG00000243156 [Sequence]  chr22:17787650-18024561 [Contig_View]  MICAL3 [Vega]
ICGC DataPortalENSG00000243156
TCGA cBioPortalMICAL3
AceView (NCBI)MICAL3
Genatlas (Paris)MICAL3
SOURCE (Princeton)MICAL3
Genetics Home Reference (NIH)MICAL3
Genomic and cartography
GoldenPath hg38 (UCSC)MICAL3  -     chr22:17787650-18024561 -  22q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MICAL3  -     22q11.21   [Description]    (hg19-Feb_2009)
GoldenPathMICAL3 - 22q11.21 [CytoView hg19]  MICAL3 - 22q11.21 [CytoView hg38]
ImmunoBaseENSG00000243156
genome Data Viewer NCBIMICAL3 [Mapview hg19]  
OMIM608882   
Gene and transcription
Genbank (Entrez)AB020626 AB037785 AK023678 AK025369 AK094822
RefSeq transcript (Entrez)NM_001122731 NM_001136004 NM_015241 NM_020793
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MICAL3
Alternative Splicing GalleryENSG00000243156
Gene ExpressionMICAL3 [ NCBI-GEO ]   MICAL3 [ EBI - ARRAY_EXPRESS ]   MICAL3 [ SEEK ]   MICAL3 [ MEM ]
Gene Expression Viewer (FireBrowse)MICAL3 [ Firebrowse - Broad ]
GenevisibleExpression of MICAL3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57553
GTEX Portal (Tissue expression)MICAL3
Human Protein AtlasENSG00000243156-MICAL3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7RTP6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7RTP6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7RTP6
Splice isoforms : SwissVarQ7RTP6
PhosPhoSitePlusQ7RTP6
Domaine pattern : Prosite (Expaxy)BMERB (PS51848)    CH (PS50021)    LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)   
Domains : Interpro (EBI)bMERB_dom    CH-domain    CH_dom_sf    FAD-bd    FAD/NAD-bd_sf    MICAL3    Znf_LIM   
Domain families : Pfam (Sanger)CH (PF00307)    DUF3585 (PF12130)    FAD_binding_3 (PF01494)    LIM (PF00412)   
Domain families : Pfam (NCBI)pfam00307    pfam12130    pfam01494    pfam00412   
Domain families : Smart (EMBL)CH (SM00033)  LIM (SM00132)  
Conserved Domain (NCBI)MICAL3
Blocks (Seattle)MICAL3
PDB (RSDB)2D88    5SZG    6ICI   
PDB Europe2D88    5SZG    6ICI   
PDB (PDBSum)2D88    5SZG    6ICI   
PDB (IMB)2D88    5SZG    6ICI   
Structural Biology KnowledgeBase2D88    5SZG    6ICI   
SCOP (Structural Classification of Proteins)2D88    5SZG    6ICI   
CATH (Classification of proteins structures)2D88    5SZG    6ICI   
SuperfamilyQ7RTP6
Human Protein Atlas [tissue]ENSG00000243156-MICAL3 [tissue]
Peptide AtlasQ7RTP6
IPIIPI00177937   IPI00480203   IPI00969176   IPI00741791   IPI00896430   IPI00979242   IPI01010424   
Protein Interaction databases
DIP (DOE-UCLA)Q7RTP6
IntAct (EBI)Q7RTP6
BioGRIDMICAL3
STRING (EMBL)MICAL3
ZODIACMICAL3
Ontologies - Pathways
QuickGOQ7RTP6
Ontology : AmiGOactin binding  actin binding  nucleus  nucleoplasm  spindle  cytosol  plasma membrane  cell cortex  exocytosis  cytoskeleton organization  cell cycle  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen  actin filament depolymerization  actin filament depolymerization  cell projection  intercellular bridge  metal ion binding  cell division  FAD binding  Flemming body  
Ontology : EGO-EBIactin binding  actin binding  nucleus  nucleoplasm  spindle  cytosol  plasma membrane  cell cortex  exocytosis  cytoskeleton organization  cell cycle  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen  actin filament depolymerization  actin filament depolymerization  cell projection  intercellular bridge  metal ion binding  cell division  FAD binding  Flemming body  
NDEx NetworkMICAL3
Atlas of Cancer Signalling NetworkMICAL3
Wikipedia pathwaysMICAL3
Orthology - Evolution
OrthoDB57553
GeneTree (enSembl)ENSG00000243156
Phylogenetic Trees/Animal Genes : TreeFamMICAL3
HOGENOMQ7RTP6
Homologs : HomoloGeneMICAL3
Homology/Alignments : Family Browser (UCSC)MICAL3
Gene fusions - Rearrangements
Fusion : QuiverMICAL3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMICAL3 [hg38]
dbVarMICAL3
ClinVarMICAL3
MonarchMICAL3
1000_GenomesMICAL3 
Exome Variant ServerMICAL3
GNOMAD BrowserENSG00000243156
Varsome BrowserMICAL3
Genomic Variants (DGV)MICAL3 [DGVbeta]
DECIPHERMICAL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMICAL3 
Mutations
ICGC Data PortalMICAL3 
TCGA Data PortalMICAL3 
Broad Tumor PortalMICAL3
OASIS PortalMICAL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMICAL3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMICAL3
Mutations and Diseases : HGMDMICAL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MICAL3
DgiDB (Drug Gene Interaction Database)MICAL3
DoCM (Curated mutations)MICAL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MICAL3 (select a term)
intoGenMICAL3
Cancer3DMICAL3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608882   
Orphanet
DisGeNETMICAL3
MedgenMICAL3
Genetic Testing Registry MICAL3
NextProtQ7RTP6 [Medical]
GENETestsMICAL3
Target ValidationMICAL3
Huge Navigator MICAL3 [HugePedia]
ClinGenMICAL3
Clinical trials, drugs, therapy
MyCancerGenomeMICAL3
Protein Interactions : CTD
Pharm GKB GenePA142671454
PharosQ7RTP6
Clinical trialMICAL3
Miscellaneous
canSAR (ICR)MICAL3 (select the gene name)
HarmonizomeMICAL3
DataMed IndexMICAL3
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMICAL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:31:44 CET 2021

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