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MICALCL (MICAL C-terminal like)

Identity

Alias_symbol (synonym)FLJ14966
Other aliasEbitein1
HGNC (Hugo) MICALCL
LocusID (NCBI) 84953
Atlas_Id 50451
Location 11p15.3  [Link to chromosome band 11p15]
Location_base_pair Starts at 12286900 and ends at 12362138 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MICALCL (11p15.3) / HS2ST1 (1p22.3)PARVA (11p15.3) / MICALCL (11p15.3)MICALCL 11p15.3 / HS2ST1 1p22.3
PARVA 11p15.3 / MICALCL 11p15.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(1;11)(p22;p15) MICALCL/HS2ST1
t(11;11)(p15;p15) PARVA/MICALCL

External links

Nomenclature
HGNC (Hugo)MICALCL   25933
Cards
Entrez_Gene (NCBI)MICALCL  84953  MICAL C-terminal like
AliasesEbitein1
GeneCards (Weizmann)MICALCL
Ensembl hg19 (Hinxton)ENSG00000133808 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000133808 [Gene_View]  ENSG00000133808 [Sequence]  chr11:12286900-12362138 [Contig_View]  MICALCL [Vega]
ICGC DataPortalENSG00000133808
TCGA cBioPortalMICALCL
AceView (NCBI)MICALCL
Genatlas (Paris)MICALCL
WikiGenes84953
SOURCE (Princeton)MICALCL
Genetics Home Reference (NIH)MICALCL
Genomic and cartography
GoldenPath hg38 (UCSC)MICALCL  -     chr11:12286900-12362138 +  11p15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MICALCL  -     11p15.3   [Description]    (hg19-Feb_2009)
EnsemblMICALCL - 11p15.3 [CytoView hg19]  MICALCL - 11p15.3 [CytoView hg38]
Mapping of homologs : NCBIMICALCL [Mapview hg19]  MICALCL [Mapview hg38]
OMIM612355   
Gene and transcription
Genbank (Entrez)AI375956 AK027872 AK123671 BK000463
RefSeq transcript (Entrez)NM_032867
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MICALCL
Cluster EST : UnigeneHs.128196 [ NCBI ]
CGAP (NCI)Hs.128196
Alternative Splicing GalleryENSG00000133808
Gene ExpressionMICALCL [ NCBI-GEO ]   MICALCL [ EBI - ARRAY_EXPRESS ]   MICALCL [ SEEK ]   MICALCL [ MEM ]
Gene Expression Viewer (FireBrowse)MICALCL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84953
GTEX Portal (Tissue expression)MICALCL
Human Protein AtlasENSG00000133808-MICALCL [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZW33   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZW33  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZW33
Splice isoforms : SwissVarQ6ZW33
PhosPhoSitePlusQ6ZW33
Domains : Interpro (EBI)DUF3585    ProQ/FinO   
Domain families : Pfam (Sanger)DUF3585 (PF12130)   
Domain families : Pfam (NCBI)pfam12130   
Domain families : Smart (EMBL)ProQ (SM00945)  
Conserved Domain (NCBI)MICALCL
DMDM Disease mutations84953
Blocks (Seattle)MICALCL
PDB (SRS)5SZH    5SZI    5SZJ    5SZK   
PDB (PDBSum)5SZH    5SZI    5SZJ    5SZK   
PDB (IMB)5SZH    5SZI    5SZJ    5SZK   
PDB (RSDB)5SZH    5SZI    5SZJ    5SZK   
Structural Biology KnowledgeBase5SZH    5SZI    5SZJ    5SZK   
SCOP (Structural Classification of Proteins)5SZH    5SZI    5SZJ    5SZK   
CATH (Classification of proteins structures)5SZH    5SZI    5SZJ    5SZK   
SuperfamilyQ6ZW33
Human Protein Atlas [tissue]ENSG00000133808-MICALCL [tissue]
Peptide AtlasQ6ZW33
HPRD08610
IPIIPI00844270   IPI00975483   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZW33
IntAct (EBI)Q6ZW33
FunCoupENSG00000133808
BioGRIDMICALCL
STRING (EMBL)MICALCL
ZODIACMICALCL
Ontologies - Pathways
QuickGOQ6ZW33
Ontology : AmiGOcytoplasm  multicellular organism development  spermatogenesis  biological_process  cell differentiation  mitogen-activated protein kinase binding  
Ontology : EGO-EBIcytoplasm  multicellular organism development  spermatogenesis  biological_process  cell differentiation  mitogen-activated protein kinase binding  
NDEx NetworkMICALCL
Atlas of Cancer Signalling NetworkMICALCL
Wikipedia pathwaysMICALCL
Orthology - Evolution
OrthoDB84953
GeneTree (enSembl)ENSG00000133808
Phylogenetic Trees/Animal Genes : TreeFamMICALCL
HOVERGENQ6ZW33
HOGENOMQ6ZW33
Homologs : HomoloGeneMICALCL
Homology/Alignments : Family Browser (UCSC)MICALCL
Gene fusions - Rearrangements
Fusion : MitelmanMICALCL/HS2ST1 [11p15.3/1p22.3]  
Fusion : MitelmanPARVA/MICALCL [11p15.3/11p15.3]  [t(11;11)(p15;p15)]  
Fusion PortalMICALCL 11p15.3 HS2ST1 1p22.3 LUSC
Fusion PortalPARVA 11p15.3 MICALCL 11p15.3 LUAD
Fusion : QuiverMICALCL
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMICALCL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MICALCL
dbVarMICALCL
ClinVarMICALCL
1000_GenomesMICALCL 
Exome Variant ServerMICALCL
ExAC (Exome Aggregation Consortium)ENSG00000133808
GNOMAD BrowserENSG00000133808
Genetic variants : HAPMAP84953
Genomic Variants (DGV)MICALCL [DGVbeta]
DECIPHERMICALCL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMICALCL 
Mutations
ICGC Data PortalMICALCL 
TCGA Data PortalMICALCL 
Broad Tumor PortalMICALCL
OASIS PortalMICALCL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMICALCL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMICALCL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MICALCL
DgiDB (Drug Gene Interaction Database)MICALCL
DoCM (Curated mutations)MICALCL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MICALCL (select a term)
intoGenMICALCL
Cancer3DMICALCL(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612355   
Orphanet
DisGeNETMICALCL
MedgenMICALCL
Genetic Testing Registry MICALCL
NextProtQ6ZW33 [Medical]
TSGene84953
GENETestsMICALCL
Target ValidationMICALCL
Huge Navigator MICALCL [HugePedia]
snp3D : Map Gene to Disease84953
BioCentury BCIQMICALCL
ClinGenMICALCL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84953
Chemical/Pharm GKB GenePA142671455
Clinical trialMICALCL
Miscellaneous
canSAR (ICR)MICALCL (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMICALCL
EVEXMICALCL
GoPubMedMICALCL
iHOPMICALCL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:35:47 CEST 2018
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