Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MID2 (midline 2)

Identity

Alias (NCBI)FXY2
MRX101
RNF60
TRIM1
XLID101
HGNC (Hugo) MID2
HGNC Alias symbFXY2
TRIM1
RNF60
MRX101
LocusID (NCBI) 11043
Atlas_Id 56701
Location Xq22.3  [Link to chromosome band Xq22]
Location_base_pair Starts at 107825866 and ends at 107931637 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARHGAP29 (1p22.1)::MID2 (Xq22.3)C2CD2 (21q22.3)::MID2 (Xq22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MID2   7096
Cards
Entrez_Gene (NCBI)MID2    midline 2
AliasesFXY2; MRX101; RNF60; TRIM1; 
XLID101
GeneCards (Weizmann)MID2
Ensembl hg19 (Hinxton)ENSG00000080561 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000080561 [Gene_View]  ENSG00000080561 [Sequence]  chrX:107825866-107931637 [Contig_View]  MID2 [Vega]
ICGC DataPortalENSG00000080561
TCGA cBioPortalMID2
AceView (NCBI)MID2
Genatlas (Paris)MID2
SOURCE (Princeton)MID2
Genetics Home Reference (NIH)MID2
Genomic and cartography
GoldenPath hg38 (UCSC)MID2  -     chrX:107825866-107931637 +  Xq22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MID2  -     Xq22.3   [Description]    (hg19-Feb_2009)
GoldenPathMID2 - Xq22.3 [CytoView hg19]  MID2 - Xq22.3 [CytoView hg38]
ImmunoBaseENSG00000080561
Genome Data Viewer NCBIMID2 [Mapview hg19]  
OMIM300204   300928   
Gene and transcription
Genbank (Entrez)AF196481 AK095034 AK123807 AY625004 BC017707
RefSeq transcript (Entrez)NM_001382751 NM_001382752 NM_012216 NM_052817
Consensus coding sequences : CCDS (NCBI)MID2
Gene ExpressionMID2 [ NCBI-GEO ]   MID2 [ EBI - ARRAY_EXPRESS ]   MID2 [ SEEK ]   MID2 [ MEM ]
Gene Expression Viewer (FireBrowse)MID2 [ Firebrowse - Broad ]
GenevisibleExpression of MID2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11043
GTEX Portal (Tissue expression)MID2
Human Protein AtlasENSG00000080561-MID2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJV3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UJV3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UJV3
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ9UJV3
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    COS (PS51262)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)B30.2/SPRY    B30.2/SPRY_sf    Bbox_C    Butyrophylin_SPRY    ConA-like_dom_sf    COS_domain    FN3_dom    FN3_sf    MID2    Midline-1_COS    SPRY/PRY_TRIM1    SPRY_dom    Znf-RING_LisH    Znf_B-box    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)COS (PF18568)    SPRY (PF00622)    zf-B_box (PF00643)    zf-RING_UBOX (PF13445)   
Domain families : Pfam (NCBI)pfam18568    pfam00622    pfam00643    pfam13445   
Domain families : Smart (EMBL)BBC (SM00502)  BBOX (SM00336)  FN3 (SM00060)  RING (SM00184)  SPRY (SM00449)  
Conserved Domain (NCBI)MID2
PDB (RSDB)2DJA    2DMK   
PDB Europe2DJA    2DMK   
PDB (PDBSum)2DJA    2DMK   
PDB (IMB)2DJA    2DMK   
Structural Biology KnowledgeBase2DJA    2DMK   
SCOP (Structural Classification of Proteins)2DJA    2DMK   
CATH (Classification of proteins structures)2DJA    2DMK   
SuperfamilyQ9UJV3
AlphaFold pdb e-kbQ9UJV3   
Human Protein Atlas [tissue]ENSG00000080561-MID2 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9UJV3
IntAct (EBI)Q9UJV3
BioGRIDMID2
STRING (EMBL)MID2
ZODIACMID2
Ontologies - Pathways
QuickGOQ9UJV3
Ontology : AmiGOtranscription coactivator activity  cytoplasm  microtubule  microtubule  microtubule binding  zinc ion binding  positive regulation of autophagy  protein ubiquitination  transferase activity  enzyme binding  negative regulation of viral transcription  protein localization to microtubule  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  suppression of viral release by host  innate immune response  positive regulation of transcription, DNA-templated  negative regulation of viral entry into host cell  positive regulation of DNA-binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  phosphoprotein binding  extracellular exosome  
Ontology : EGO-EBItranscription coactivator activity  cytoplasm  microtubule  microtubule  microtubule binding  zinc ion binding  positive regulation of autophagy  protein ubiquitination  transferase activity  enzyme binding  negative regulation of viral transcription  protein localization to microtubule  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  suppression of viral release by host  innate immune response  positive regulation of transcription, DNA-templated  negative regulation of viral entry into host cell  positive regulation of DNA-binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  phosphoprotein binding  extracellular exosome  
NDEx NetworkMID2
Atlas of Cancer Signalling NetworkMID2
Wikipedia pathwaysMID2
Orthology - Evolution
OrthoDB11043
GeneTree (enSembl)ENSG00000080561
Phylogenetic Trees/Animal Genes : TreeFamMID2
Homologs : HomoloGeneMID2
Homology/Alignments : Family Browser (UCSC)MID2
Gene fusions - Rearrangements
Fusion : QuiverMID2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMID2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MID2
dbVarMID2
ClinVarMID2
MonarchMID2
1000_GenomesMID2 
Exome Variant ServerMID2
GNOMAD BrowserENSG00000080561
Varsome BrowserMID2
ACMGMID2 variants
VarityQ9UJV3
Genomic Variants (DGV)MID2 [DGVbeta]
DECIPHERMID2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMID2 
Mutations
ICGC Data PortalMID2 
TCGA Data PortalMID2 
Broad Tumor PortalMID2
OASIS PortalMID2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMID2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMID2
Mutations and Diseases : HGMDMID2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMID2
DgiDB (Drug Gene Interaction Database)MID2
DoCM (Curated mutations)MID2
CIViC (Clinical Interpretations of Variants in Cancer)MID2
Cancer3DMID2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300204    300928   
Orphanet3256   
DisGeNETMID2
MedgenMID2
Genetic Testing Registry MID2
NextProtQ9UJV3 [Medical]
GENETestsMID2
Target ValidationMID2
Huge Navigator MID2 [HugePedia]
ClinGenMID2
Clinical trials, drugs, therapy
MyCancerGenomeMID2
Protein Interactions : CTDMID2
Pharm GKB GenePA30817
PharosQ9UJV3
Clinical trialMID2
Miscellaneous
canSAR (ICR)MID2
HarmonizomeMID2
ARCHS4MID2
DataMed IndexMID2
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMID2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 20 12:44:08 CET 2022

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.