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MIDN (midnolin)

Identity

Alias (NCBI)-
HGNC (Hugo) MIDN
LocusID (NCBI) 90007
Atlas_Id 54458
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 1248553 and ends at 1259143 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MIDN (19p13.3) / ARL8A (1q32.1)MIDN (19p13.3) / MAP7D1 (1p34.3)MIDN (19p13.3) / MIDN (19p13.3)
MIDN (19p13.3) / SBNO2 (19p13.3)MIDN (19p13.3) / TM4SF1 (3q25.1)PRPF40B (12q13.12) / MIDN (19p13.3)
PSMB2 (1p34.3) / MIDN (19p13.3)STK11 (19p13.3) / MIDN (19p13.3)MIDN 19p13.3 / MAP7D1 1p34.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(1;19)(p34;p13) MIDN/MAP7D1
MIDN/SBNO2 (19p13)
STK11/MIDN (19p13)

External links

Nomenclature
HGNC (Hugo)MIDN   16298
Cards
Entrez_Gene (NCBI)MIDN    midnolin
Aliases
GeneCards (Weizmann)MIDN
Ensembl hg19 (Hinxton)ENSG00000167470 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167470 [Gene_View]  ENSG00000167470 [Sequence]  chr19:1248553-1259143 [Contig_View]  MIDN [Vega]
ICGC DataPortalENSG00000167470
TCGA cBioPortalMIDN
AceView (NCBI)MIDN
Genatlas (Paris)MIDN
SOURCE (Princeton)MIDN
Genetics Home Reference (NIH)MIDN
Genomic and cartography
GoldenPath hg38 (UCSC)MIDN  -     chr19:1248553-1259143 +  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MIDN  -     19p13.3   [Description]    (hg19-Feb_2009)
GoldenPathMIDN - 19p13.3 [CytoView hg19]  MIDN - 19p13.3 [CytoView hg38]
ImmunoBaseENSG00000167470
genome Data Viewer NCBIMIDN [Mapview hg19]  
OMIM606700   
Gene and transcription
Genbank (Entrez)AA421908 AK075506 BC015089 BC060848 BC094778
RefSeq transcript (Entrez)NM_177401
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MIDN
Alternative Splicing GalleryENSG00000167470
Gene ExpressionMIDN [ NCBI-GEO ]   MIDN [ EBI - ARRAY_EXPRESS ]   MIDN [ SEEK ]   MIDN [ MEM ]
Gene Expression Viewer (FireBrowse)MIDN [ Firebrowse - Broad ]
GenevisibleExpression of MIDN in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)90007
GTEX Portal (Tissue expression)MIDN
Human Protein AtlasENSG00000167470-MIDN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ504T8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ504T8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ504T8
Splice isoforms : SwissVarQ504T8
PhosPhoSitePlusQ504T8
Domaine pattern : Prosite (Expaxy)UBIQUITIN_2 (PS50053)   
Domains : Interpro (EBI)Midnolin    Ubiquitin-like_dom    Ubiquitin-like_domsf   
Domain families : Pfam (Sanger)ubiquitin (PF00240)   
Domain families : Pfam (NCBI)pfam00240   
Domain families : Smart (EMBL)UBQ (SM00213)  
Conserved Domain (NCBI)MIDN
Blocks (Seattle)MIDN
SuperfamilyQ504T8
Human Protein Atlas [tissue]ENSG00000167470-MIDN [tissue]
Peptide AtlasQ504T8
HPRD16230
IPIIPI00164432   
Protein Interaction databases
DIP (DOE-UCLA)Q504T8
IntAct (EBI)Q504T8
BioGRIDMIDN
STRING (EMBL)MIDN
ZODIACMIDN
Ontologies - Pathways
QuickGOQ504T8
Ontology : AmiGOmolecular_function  nucleus  nucleus  nucleolus  cytoplasm  cytosol  biological_process  kinase binding  negative regulation of glucokinase activity  negative regulation of insulin secretion  
Ontology : EGO-EBImolecular_function  nucleus  nucleus  nucleolus  cytoplasm  cytosol  biological_process  kinase binding  negative regulation of glucokinase activity  negative regulation of insulin secretion  
NDEx NetworkMIDN
Atlas of Cancer Signalling NetworkMIDN
Wikipedia pathwaysMIDN
Orthology - Evolution
OrthoDB90007
GeneTree (enSembl)ENSG00000167470
Phylogenetic Trees/Animal Genes : TreeFamMIDN
HOGENOMQ504T8
Homologs : HomoloGeneMIDN
Homology/Alignments : Family Browser (UCSC)MIDN
Gene fusions - Rearrangements
Fusion : MitelmanMIDN/MAP7D1 [19p13.3/1p34.3]  
Fusion : MitelmanMIDN/SBNO2 [19p13.3/19p13.3]  
Fusion : MitelmanSTK11/MIDN [19p13.3/19p13.3]  
Fusion PortalMIDN 19p13.3 MAP7D1 1p34.3 OV
Fusion Cancer (Beijing)PSMB2 [1p34.3]  -  MIDN [19p13.3]  [FUSC001090]
Fusion : QuiverMIDN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMIDN [hg38]
dbVarMIDN
ClinVarMIDN
MonarchMIDN
1000_GenomesMIDN 
Exome Variant ServerMIDN
GNOMAD BrowserENSG00000167470
Varsome BrowserMIDN
Genomic Variants (DGV)MIDN [DGVbeta]
DECIPHERMIDN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMIDN 
Mutations
ICGC Data PortalMIDN 
TCGA Data PortalMIDN 
Broad Tumor PortalMIDN
OASIS PortalMIDN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMIDN  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMIDN
Mutations and Diseases : HGMDMIDN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MIDN
DgiDB (Drug Gene Interaction Database)MIDN
DoCM (Curated mutations)MIDN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MIDN (select a term)
intoGenMIDN
Cancer3DMIDN(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606700   
Orphanet
DisGeNETMIDN
MedgenMIDN
Genetic Testing Registry MIDN
NextProtQ504T8 [Medical]
GENETestsMIDN
Target ValidationMIDN
Huge Navigator MIDN [HugePedia]
ClinGenMIDN
Clinical trials, drugs, therapy
MyCancerGenomeMIDN
Protein Interactions : CTD
Pharm GKB GenePA30818
PharosQ504T8
Clinical trialMIDN
Miscellaneous
canSAR (ICR)MIDN (select the gene name)
HarmonizomeMIDN
DataMed IndexMIDN
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMIDN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:24:51 CET 2021
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