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MIEF2 (mitochondrial elongation factor 2)

Identity

Alias_namesSMCR7
Smith-Magenis syndrome chromosome region
Alias_symbol (synonym)MGC23130
MiD49
Other aliasMID49
HGNC (Hugo) MIEF2
LocusID (NCBI) 125170
Atlas_Id 56427
Location 17p11.2  [Link to chromosome band 17p11]
Location_base_pair Starts at 18260534 and ends at 18265781 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MIEF2   17920
Cards
Entrez_Gene (NCBI)MIEF2  125170  mitochondrial elongation factor 2
AliasesMID49; SMCR7
GeneCards (Weizmann)MIEF2
Ensembl hg19 (Hinxton)ENSG00000177427 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000177427 [Gene_View]  chr17:18260534-18265781 [Contig_View]  MIEF2 [Vega]
ICGC DataPortalENSG00000177427
TCGA cBioPortalMIEF2
AceView (NCBI)MIEF2
Genatlas (Paris)MIEF2
WikiGenes125170
SOURCE (Princeton)MIEF2
Genetics Home Reference (NIH)MIEF2
Genomic and cartography
GoldenPath hg38 (UCSC)MIEF2  -     chr17:18260534-18265781 +  17p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MIEF2  -     17p11.2   [Description]    (hg19-Feb_2009)
EnsemblMIEF2 - 17p11.2 [CytoView hg19]  MIEF2 - 17p11.2 [CytoView hg38]
Mapping of homologs : NCBIMIEF2 [Mapview hg19]  MIEF2 [Mapview hg38]
OMIM615498   
Gene and transcription
Genbank (Entrez)AF467443 AK056165 AK128310 BC014973 BC035292
RefSeq transcript (Entrez)NM_001144900 NM_139162 NM_148886
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MIEF2
Cluster EST : UnigeneHs.655555 [ NCBI ]
CGAP (NCI)Hs.655555
Alternative Splicing GalleryENSG00000177427
Gene ExpressionMIEF2 [ NCBI-GEO ]   MIEF2 [ EBI - ARRAY_EXPRESS ]   MIEF2 [ SEEK ]   MIEF2 [ MEM ]
Gene Expression Viewer (FireBrowse)MIEF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)125170
GTEX Portal (Tissue expression)MIEF2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96C03   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96C03  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96C03
Splice isoforms : SwissVarQ96C03
PhosPhoSitePlusQ96C03
Domains : Interpro (EBI)Mab-21_dom   
Domain families : Pfam (Sanger)Mab-21 (PF03281)   
Domain families : Pfam (NCBI)pfam03281   
Domain families : Smart (EMBL)Mab-21 (SM01265)  
Conserved Domain (NCBI)MIEF2
DMDM Disease mutations125170
Blocks (Seattle)MIEF2
SuperfamilyQ96C03
Human Protein AtlasENSG00000177427
Peptide AtlasQ96C03
HPRD18074
IPIIPI00060146   IPI00443814   IPI00789548   IPI00790309   
Protein Interaction databases
DIP (DOE-UCLA)Q96C03
IntAct (EBI)Q96C03
FunCoupENSG00000177427
BioGRIDMIEF2
STRING (EMBL)MIEF2
ZODIACMIEF2
Ontologies - Pathways
QuickGOQ96C03
Ontology : AmiGOprotein binding  mitochondrion  mitochondrial outer membrane  peroxisome  mitochondrion organization  mitochondrial fusion  integral component of membrane  positive regulation of protein homooligomerization  positive regulation of mitochondrial fission  positive regulation of mitochondrial fission  positive regulation of protein targeting to membrane  positive regulation of protein targeting to membrane  
Ontology : EGO-EBIprotein binding  mitochondrion  mitochondrial outer membrane  peroxisome  mitochondrion organization  mitochondrial fusion  integral component of membrane  positive regulation of protein homooligomerization  positive regulation of mitochondrial fission  positive regulation of mitochondrial fission  positive regulation of protein targeting to membrane  positive regulation of protein targeting to membrane  
NDEx NetworkMIEF2
Atlas of Cancer Signalling NetworkMIEF2
Wikipedia pathwaysMIEF2
Orthology - Evolution
OrthoDB125170
GeneTree (enSembl)ENSG00000177427
Phylogenetic Trees/Animal Genes : TreeFamMIEF2
HOVERGENQ96C03
HOGENOMQ96C03
Homologs : HomoloGeneMIEF2
Homology/Alignments : Family Browser (UCSC)MIEF2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMIEF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MIEF2
dbVarMIEF2
ClinVarMIEF2
1000_GenomesMIEF2 
Exome Variant ServerMIEF2
ExAC (Exome Aggregation Consortium)MIEF2 (select the gene name)
Genetic variants : HAPMAP125170
Genomic Variants (DGV)MIEF2 [DGVbeta]
DECIPHERMIEF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMIEF2 
Mutations
ICGC Data PortalMIEF2 
TCGA Data PortalMIEF2 
Broad Tumor PortalMIEF2
OASIS PortalMIEF2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMIEF2
BioMutasearch MIEF2
DgiDB (Drug Gene Interaction Database)MIEF2
DoCM (Curated mutations)MIEF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MIEF2 (select a term)
intoGenMIEF2
Cancer3DMIEF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615498   
Orphanet
MedgenMIEF2
Genetic Testing Registry MIEF2
NextProtQ96C03 [Medical]
TSGene125170
GENETestsMIEF2
Huge Navigator MIEF2 [HugePedia]
snp3D : Map Gene to Disease125170
BioCentury BCIQMIEF2
ClinGenMIEF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD125170
Chemical/Pharm GKB GenePA38265
Clinical trialMIEF2
Miscellaneous
canSAR (ICR)MIEF2 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMIEF2
EVEXMIEF2
GoPubMedMIEF2
iHOPMIEF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:24:56 CEST 2017

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