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MINDY2 (MINDY lysine 48 deubiquitinase 2)

Identity

Alias_namesFAM63B
family with sequence similarity 63, member B
family with sequence similarity 63 member B
MINDY deubiquitinase 2
Alias_symbol (synonym)KIAA1164
Other alias
HGNC (Hugo) MINDY2
LocusID (NCBI) 54629
Atlas_Id 79477
Location 15q21.3  [Link to chromosome band 15q21]
Location_base_pair Starts at 58771192 and ends at 58861899 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MINDY2   26954
Cards
Entrez_Gene (NCBI)MINDY2  54629  MINDY lysine 48 deubiquitinase 2
AliasesFAM63B
GeneCards (Weizmann)MINDY2
Ensembl hg19 (Hinxton)ENSG00000128923 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128923 [Gene_View]  chr15:58771192-58861899 [Contig_View]  MINDY2 [Vega]
ICGC DataPortalENSG00000128923
TCGA cBioPortalMINDY2
AceView (NCBI)MINDY2
Genatlas (Paris)MINDY2
WikiGenes54629
SOURCE (Princeton)MINDY2
Genetics Home Reference (NIH)MINDY2
Genomic and cartography
GoldenPath hg38 (UCSC)MINDY2  -     chr15:58771192-58861899 +  15q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MINDY2  -     15q21.3   [Description]    (hg19-Feb_2009)
EnsemblMINDY2 - 15q21.3 [CytoView hg19]  MINDY2 - 15q21.3 [CytoView hg38]
Mapping of homologs : NCBIMINDY2 [Mapview hg19]  MINDY2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB032990 AB075509 AK021710 AK022891 AK075319
RefSeq transcript (Entrez)NM_001040450 NM_001040453 NM_019092
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MINDY2
Cluster EST : UnigeneHs.595286 [ NCBI ]
CGAP (NCI)Hs.595286
Alternative Splicing GalleryENSG00000128923
Gene ExpressionMINDY2 [ NCBI-GEO ]   MINDY2 [ EBI - ARRAY_EXPRESS ]   MINDY2 [ SEEK ]   MINDY2 [ MEM ]
Gene Expression Viewer (FireBrowse)MINDY2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54629
GTEX Portal (Tissue expression)MINDY2
Human Protein AtlasENSG00000128923-MINDY2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NBR6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NBR6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NBR6
Splice isoforms : SwissVarQ8NBR6
PhosPhoSitePlusQ8NBR6
Domains : Interpro (EBI)MINDY    MINDY_domain   
Domain families : Pfam (Sanger)DUF544 (PF04424)   
Domain families : Pfam (NCBI)pfam04424   
Conserved Domain (NCBI)MINDY2
DMDM Disease mutations54629
Blocks (Seattle)MINDY2
SuperfamilyQ8NBR6
Human Protein Atlas [tissue]ENSG00000128923-MINDY2 [tissue]
Peptide AtlasQ8NBR6
IPIIPI00744140   IPI00748812   IPI00654835   
Protein Interaction databases
DIP (DOE-UCLA)Q8NBR6
IntAct (EBI)Q8NBR6
FunCoupENSG00000128923
BioGRIDMINDY2
STRING (EMBL)MINDY2
ZODIACMINDY2
Ontologies - Pathways
QuickGOQ8NBR6
Ontology : AmiGOthiol-dependent ubiquitin-specific protease activity  nucleoplasm  biological_process  cysteine-type carboxypeptidase activity  K48-linked polyubiquitin modification-dependent protein binding  K63-linked polyubiquitin modification-dependent protein binding  protein K48-linked deubiquitination  K11-linked polyubiquitin modification-dependent protein binding  K6-linked polyubiquitin modification-dependent protein binding  Lys48-specific deubiquitinase activity  
Ontology : EGO-EBIthiol-dependent ubiquitin-specific protease activity  nucleoplasm  biological_process  cysteine-type carboxypeptidase activity  K48-linked polyubiquitin modification-dependent protein binding  K63-linked polyubiquitin modification-dependent protein binding  protein K48-linked deubiquitination  K11-linked polyubiquitin modification-dependent protein binding  K6-linked polyubiquitin modification-dependent protein binding  Lys48-specific deubiquitinase activity  
NDEx NetworkMINDY2
Atlas of Cancer Signalling NetworkMINDY2
Wikipedia pathwaysMINDY2
Orthology - Evolution
OrthoDB54629
GeneTree (enSembl)ENSG00000128923
Phylogenetic Trees/Animal Genes : TreeFamMINDY2
HOVERGENQ8NBR6
HOGENOMQ8NBR6
Homologs : HomoloGeneMINDY2
Homology/Alignments : Family Browser (UCSC)MINDY2
Gene fusions - Rearrangements
Tumor Fusion PortalMINDY2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMINDY2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MINDY2
dbVarMINDY2
ClinVarMINDY2
1000_GenomesMINDY2 
Exome Variant ServerMINDY2
ExAC (Exome Aggregation Consortium)ENSG00000128923
GNOMAD BrowserENSG00000128923
Genetic variants : HAPMAP54629
Genomic Variants (DGV)MINDY2 [DGVbeta]
DECIPHERMINDY2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMINDY2 
Mutations
ICGC Data PortalMINDY2 
TCGA Data PortalMINDY2 
Broad Tumor PortalMINDY2
OASIS PortalMINDY2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMINDY2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MINDY2
DgiDB (Drug Gene Interaction Database)MINDY2
DoCM (Curated mutations)MINDY2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MINDY2 (select a term)
intoGenMINDY2
Cancer3DMINDY2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETMINDY2
MedgenMINDY2
Genetic Testing Registry MINDY2
NextProtQ8NBR6 [Medical]
TSGene54629
GENETestsMINDY2
Target ValidationMINDY2
Huge Navigator MINDY2 [HugePedia]
snp3D : Map Gene to Disease54629
BioCentury BCIQMINDY2
ClinGenMINDY2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54629
Chemical/Pharm GKB GenePA142671873
Clinical trialMINDY2
Miscellaneous
canSAR (ICR)MINDY2 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMINDY2
EVEXMINDY2
GoPubMedMINDY2
iHOPMINDY2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:31:41 CET 2017

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