Identity
HGNC
LOCATION
10q23.2
LOCUSID
ALIAS
HIPER1,MINPP2,MIPP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9562
MIM: 605391
HGNC: 7102
Ensembl: ENSG00000107789
Variants:
dbSNP: 9562
ClinVar: 9562
TCGA: ENSG00000107789
COSMIC: MINPP1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000107789 | ENST00000371994 | Q9UNW1 |
| ENSG00000107789 | ENST00000371996 | Q9UNW1 |
| ENSG00000107789 | ENST00000536010 | Q9UNW1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33168985 | 2021 | Pontocerebellar hypoplasia due to bi-allelic variants in MINPP1. | 6 |
| 33168985 | 2021 | Pontocerebellar hypoplasia due to bi-allelic variants in MINPP1. | 6 |
| 33257696 | 2020 | MINPP1 prevents intracellular accumulation of the chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia. | 17 |
| 33257696 | 2020 | MINPP1 prevents intracellular accumulation of the chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia. | 17 |
| 27038811 | 2016 | Endoplasmic reticulum stress-induced apoptosis accompanies enhanced expression of multiple inositol polyphosphate phosphatase 1 (Minpp1): a possible role for Minpp1 in cellular stress response. | 17 |
| 27038811 | 2016 | Endoplasmic reticulum stress-induced apoptosis accompanies enhanced expression of multiple inositol polyphosphate phosphatase 1 (Minpp1): a possible role for Minpp1 in cellular stress response. | 17 |
| 23186306 | 2013 | Tumour cells can employ extracellular Ins(1,2,3,4,5,6)P(6) and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation. | 31 |
| 23186306 | 2013 | Tumour cells can employ extracellular Ins(1,2,3,4,5,6)P(6) and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation. | 31 |
| 21071540 | 2011 | Validation of genome-wide prostate cancer associations in men of African descent. | 59 |
| 21071540 | 2011 | Validation of genome-wide prostate cancer associations in men of African descent. | 59 |
| 20304771 | 2010 | A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. | 78 |
| 20304771 | 2010 | A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. | 78 |
| 16385451 | 2006 | A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. | 83 |
| 16385451 | 2006 | A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. | 83 |
Citation
Dessen P
MINPP1 (multiple inositol-polyphosphate phosphatase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41366/minpp1
