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MIP (major intrinsic protein of lens fiber)

Identity

Alias_symbol (synonym)MP26
LIM1
AQP0
Other aliasCTRCT15
MIP26
HGNC (Hugo) MIP
LocusID (NCBI) 4284
Atlas_Id 68994
Location 12q13.3  [Link to chromosome band 12q13]
Location_base_pair Starts at 56449502 and ends at 56454651 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PAN2 (12q13.3) / MIP (12q13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MIP   7103
Cards
Entrez_Gene (NCBI)MIP  4284  major intrinsic protein of lens fiber
AliasesAQP0; CTRCT15; LIM1; MIP26; 
MP26
GeneCards (Weizmann)MIP
Ensembl hg19 (Hinxton)ENSG00000135517 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135517 [Gene_View]  chr12:56449502-56454651 [Contig_View]  MIP [Vega]
ICGC DataPortalENSG00000135517
TCGA cBioPortalMIP
AceView (NCBI)MIP
Genatlas (Paris)MIP
WikiGenes4284
SOURCE (Princeton)MIP
Genetics Home Reference (NIH)MIP
Genomic and cartography
GoldenPath hg38 (UCSC)MIP  -     chr12:56449502-56454651 -  12q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MIP  -     12q13.3   [Description]    (hg19-Feb_2009)
EnsemblMIP - 12q13.3 [CytoView hg19]  MIP - 12q13.3 [CytoView hg38]
Mapping of homologs : NCBIMIP [Mapview hg19]  MIP [Mapview hg38]
OMIM154050   615274   
Gene and transcription
Genbank (Entrez)AK307357 BC074913 BC117474 BM696300 BM705396
RefSeq transcript (Entrez)NM_012064
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MIP
Cluster EST : UnigeneHs.574026 [ NCBI ]
CGAP (NCI)Hs.574026
Alternative Splicing GalleryENSG00000135517
Gene ExpressionMIP [ NCBI-GEO ]   MIP [ EBI - ARRAY_EXPRESS ]   MIP [ SEEK ]   MIP [ MEM ]
Gene Expression Viewer (FireBrowse)MIP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4284
GTEX Portal (Tissue expression)MIP
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30301   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30301  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30301
Splice isoforms : SwissVarP30301
PhosPhoSitePlusP30301
Domaine pattern : Prosite (Expaxy)MIP (PS00221)   
Domains : Interpro (EBI)Aquaporin-like    Aquaporin_transptr    MIP    MIP_CS   
Domain families : Pfam (Sanger)MIP (PF00230)   
Domain families : Pfam (NCBI)pfam00230   
Conserved Domain (NCBI)MIP
DMDM Disease mutations4284
Blocks (Seattle)MIP
SuperfamilyP30301
Human Protein AtlasENSG00000135517
Peptide AtlasP30301
HPRD01098
IPIIPI00026069   
Protein Interaction databases
DIP (DOE-UCLA)P30301
IntAct (EBI)P30301
FunCoupENSG00000135517
BioGRIDMIP
STRING (EMBL)MIP
ZODIACMIP
Ontologies - Pathways
QuickGOP30301
Ontology : AmiGOlens development in camera-type eye  structural constituent of eye lens  calmodulin binding  endoplasmic reticulum  plasma membrane  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  gap junction  water transport  water transport  visual perception  water channel activity  water channel activity  water channel activity  apical plasma membrane  ion transmembrane transport  positive regulation of cell adhesion  response to stimulus  protein homotetramerization  gap junction-mediated intercellular transport  
Ontology : EGO-EBIlens development in camera-type eye  structural constituent of eye lens  calmodulin binding  endoplasmic reticulum  plasma membrane  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  gap junction  water transport  water transport  visual perception  water channel activity  water channel activity  water channel activity  apical plasma membrane  ion transmembrane transport  positive regulation of cell adhesion  response to stimulus  protein homotetramerization  gap junction-mediated intercellular transport  
NDEx NetworkMIP
Atlas of Cancer Signalling NetworkMIP
Wikipedia pathwaysMIP
Orthology - Evolution
OrthoDB4284
GeneTree (enSembl)ENSG00000135517
Phylogenetic Trees/Animal Genes : TreeFamMIP
HOVERGENP30301
HOGENOMP30301
Homologs : HomoloGeneMIP
Homology/Alignments : Family Browser (UCSC)MIP
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMIP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MIP
dbVarMIP
ClinVarMIP
1000_GenomesMIP 
Exome Variant ServerMIP
ExAC (Exome Aggregation Consortium)MIP (select the gene name)
Genetic variants : HAPMAP4284
Genomic Variants (DGV)MIP [DGVbeta]
DECIPHERMIP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMIP 
Mutations
ICGC Data PortalMIP 
TCGA Data PortalMIP 
Broad Tumor PortalMIP
OASIS PortalMIP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMIP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMIP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MIP
DgiDB (Drug Gene Interaction Database)MIP
DoCM (Curated mutations)MIP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MIP (select a term)
intoGenMIP
Cancer3DMIP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM154050    615274   
Orphanet23423    14006    14002    14008    14011    14010   
MedgenMIP
Genetic Testing Registry MIP
NextProtP30301 [Medical]
TSGene4284
GENETestsMIP
Target ValidationMIP
Huge Navigator MIP [HugePedia]
snp3D : Map Gene to Disease4284
BioCentury BCIQMIP
ClinGenMIP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4284
Chemical/Pharm GKB GenePA30821
Clinical trialMIP
Miscellaneous
canSAR (ICR)MIP (select the gene name)
Probes
Litterature
PubMed80 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMIP
EVEXMIP
GoPubMedMIP
iHOPMIP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:27:26 CEST 2017

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