MIR1246 (microRNA 1246)

2012-12-01  

Identity

HGNC
LOCATION
2q31.1
LOCUSID
ALIAS
MIRN1246,hsa-mir-1246

Other Information

Locus ID:

NCBI: 100302142
HGNC: 35312
Ensembl: ENSG00000283203
miRBase:

Variants:

dbSNP: 100302142
ClinVar: 100302142
TCGA: ENSG00000283203
COSMIC: MIR1246

RNA/Proteins

References

Pubmed IDYearTitleCitations
294726162018Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246.65
251178112014MicroRNA-1246 expression associated with CCNG2-mediated chemoresistance and stemness in pancreatic cancer.52
279291182016Exosomal microRNA miR-1246 induces cell motility and invasion through the regulation of DENND2D in oral squamous cell carcinoma.46
251594942014MicroRNA-1246 enhances migration and invasion through CADM1 in hepatocellular carcinoma.42
271291662016Extracellular miR-1246 promotes lung cancer cell proliferation and enhances radioresistance by directly targeting DR5.28
265733782016MicroRNA-1246 promotes growth and metastasis of colorectal cancer cells involving CCNG2 reduction.20
300383242018Exosome-packaged miR-1246 contributes to bystander DNA damage by targeting LIG4.17
256280402015Overexpression of miR-595 and miR-1246 in the sera of patients with active forms of inflammatory bowel disease.13
314850192020Hypoxic glioma-derived exosomes deliver microRNA-1246 to induce M2 macrophage polarization by targeting TERF2IP via the STAT3 and NF-κB pathways.13
247399542014Parallel mRNA and microRNA profiling of HEV71-infected human neuroblastoma cells reveal the up-regulation of miR-1246 in association with DLG3 repression.12

Citation

Dessen P

MIR1246 (microRNA 1246)

Atlas Genet Cytogenet Oncol Haematol. 2012-12-01

Online version: http://atlasgeneticsoncology.org/gene/53065/mir1246