MIR130B (microRNA 130b)

2011-10-01  

Identity

HGNC
LOCATION
22q11.21
LOCUSID
ALIAS
MIRN130B,mir-130b

Other Information

Locus ID:

NCBI: 406920
MIM: 613682
HGNC: 31515
Ensembl: ENSG00000283871
miRBase:

Variants:

dbSNP: 406920
ClinVar: 406920
TCGA: ENSG00000283871
COSMIC: MIR130B

RNA/Proteins

Expression (GTEx)

0
1

References

Pubmed IDYearTitleCitations
228476132013Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis.121
189741422008Roles for microRNAs, miR-93 and miR-130b, and tumor protein 53-induced nuclear protein 1 tumor suppressor in cell growth dysregulation by human T-cell lymphotrophic virus 1.75
244685852014MiR-20b, -21, and -130b inhibit PTEN expression resulting in B7-H1 over-expression in advanced colorectal cancer.64
240274332013MicroRNA-130b promotes tumor development and is associated with poor prognosis in colorectal cancer.57
240400782013MiR-130b is a prognostic marker and inhibits cell proliferation and invasion in pancreatic cancer through targeting STAT3.55
281650662017MicroRNA-130b targets PTEN to mediate drug resistance and proliferation of breast cancer cells via the PI3K/Akt signaling pathway.39
256375142015MiR-130b plays an oncogenic role by repressing PTEN expression in esophageal squamous cell carcinoma cells.34
233925772013miR-130b is an EMT-related microRNA that targets DICER1 for aggression in endometrial cancer.26
251547412015MiR-130b suppresses prostate cancer metastasis through down-regulation of MMP2.21
312289372019Circular RNA circSLC8A1 acts as a sponge of miR-130b/miR-494 in suppressing bladder cancer progression via regulating PTEN.21

Citation

Dessen P

MIR130B (microRNA 130b)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52426/mir130b