MIR135B (microRNA 135b)

2012-03-01  

Identity

HGNC
MIR135B
LOCATION
1q32.1
LOCUSID
442891
ALIAS
MIRN135B,mir-135b

Other Information

Locus ID:

NCBI: 442891
HGNC: 31760
Ensembl: ENSG00000199059
miRBase:

Variants:

dbSNP: 442891
ClinVar: 442891
TCGA: ENSG00000199059
COSMIC: MIR135B

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
253202452014Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1.148
236956712013MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1.107
220426992011miR-135b mediates NPM-ALK-driven oncogenicity and renders IL-17-producing immunophenotype to anaplastic large cell lymphoma.62
254164472015MiR-135b promotes proliferation and invasion of osteosarcoma cells via targeting FOXO1.27
255375162015MicroRNA-135b, a HSF1 target, promotes tumor invasion and metastasis by regulating RECK and EVI5 in hepatocellular carcinoma.27
261849782015MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C.27
252653362014miR-135b contributes to the radioresistance by targeting GSK3β in human glioblastoma multiforme cells.23
248026702014MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF-β/BMP signaling.22
276611142016miR-135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone.19
281170282017Long Noncoding RNA GAS5 Inhibits Tumorigenesis and Enhances Radiosensitivity by Suppressing miR-135b Expression in Non-Small Cell Lung Cancer.18

Citation

Dessen P

MIR135B (microRNA 135b)

Atlas Genet Cytogenet Oncol Haematol. 2012-03-01

Online version: http://atlasgeneticsoncology.org/gene/52652/mir135b