MIR146A (microRNA 146a)

2008-07-01  

Identity

HGNC
MIR146A
LOCATION
5q33.3
LOCUSID
406938
ALIAS
MIRN146,MIRN146A,miR-146a,miRNA146A

Other Information

Locus ID:

NCBI: 406938
MIM: 610566
HGNC: 31533
Ensembl: ENSG00000283733
miRBase:

Variants:

dbSNP: 406938
ClinVar: 406938
TCGA: ENSG00000283733
COSMIC: MIR146A

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
163652912005The role of microRNA genes in papillary thyroid carcinoma.382
184748712008Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma.281
183833922008Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis.267
236193652013MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy.120
199656512010An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes.107
209378402010Differential regulation of interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-2 by microRNA-146a and NF-kappaB in stressed human astroglial cells and in Alzheimer disease.102
245616232014MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells.97
214729902011Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers.96
191389932008Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk.95
185680192008A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis.78

Citation

Dessen P

MIR146A (microRNA 146a)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50195/mir146a