MIR149 (microRNA 149)

2011-10-01  

Identity

HGNC
LOCATION
2q37.3
LOCUSID
ALIAS
MIRN149,mir-149

Other Information

Locus ID:

NCBI: 406941
MIM: 615209
HGNC: 31536
Ensembl: ENSG00000207611
miRBase:

Variants:

dbSNP: 406941
ClinVar: 406941
TCGA: ENSG00000207611
COSMIC: MIR149

RNA/Proteins

Expression (GTEx)

0
1

References

Pubmed IDYearTitleCitations
218967532011MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma.67
307177512019Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway.62
228217292013SP1 mediates the link between methylation of the tumour suppressor miR-149 and outcome in colorectal cancer.56
246084342014MicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasis.53
199502262010Single nucleotide polymorphisms in miRNA binding sites and miRNA genes as breast/ovarian cancer risk modifiers in Jewish high-risk women.45
206236442010miR-149* induces apoptosis by inhibiting Akt1 and E2F1 in human cancer cells.44
226474172013The human MTHFR rs4846049 polymorphism increases coronary heart disease risk through modifying miRNA binding.31
256139032015MicroRNA-149 suppresses colorectal cancer cell migration and invasion by directly targeting forkhead box transcription factor FOXM1.31
289873452018LncRNA-LINC00460 facilitates nasopharyngeal carcinoma tumorigenesis through sponging miR-149-5p to up-regulate IL6.30
231150502013Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer.29

Citation

Dessen P

MIR149 (microRNA 149)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52414/mir149