MIR16-2 (microRNA 16-2)

2011-02-01  

Identity

HGNC
LOCATION
3q25.33
LOCUSID
ALIAS
MIRN16-2,mir-16-2,mir-16-3

Other Information

Locus ID:

NCBI: 406951
HGNC: 31546
Ensembl: ENSG00000198987
miRBase:

Variants:

dbSNP: 406951
ClinVar: 406951
TCGA: ENSG00000198987
COSMIC: MIR16-2

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
236863102014Dysregulation of BMI1 and microRNA-16 collaborate to enhance an anti-apoptotic potential in the side population of refractory mantle cell lymphoma.21
263505362015MicroRNA-16-5p Controls Development of Osteoarthritis by Targeting SMAD3 in Chondrocytes.16
264998862015Suppressive effects of microRNA-16 on the proliferation, invasion and metastasis of hepatocellular carcinoma cells.15
258304802015MicroRNA-16 modulates HuR regulation of cyclin E1 in breast cancer cells.12
311022732019microRNA-16-5p-containing exosomes derived from bone marrow-derived mesenchymal stem cells inhibit proliferation, migration, and invasion, while promoting apoptosis of colorectal cancer cells by downregulating ITGA2.12
267224592015MiR-16 modulate temozolomide resistance by regulating BCL-2 in human glioma cells.11
291388332018miR-16 mimics inhibit TGF-β1-induced epithelial-to-mesenchymal transition via activation of autophagy in non-small cell lung carcinoma cells.8
293599632018Melatonin Inhibits the Proliferation of Gastric Cancer Cells Through Regulating the miR-16-5p-Smad3 Pathway.7
302525872018Loss of miR-16 contributes to tumor progression by activation of tousled-like kinase 1 in oral squamous cell carcinoma.7
310182442019MiR-16-1-3p and miR-16-2-3p possess strong tumor suppressive and antimetastatic properties in osteosarcoma.6

Citation

Dessen P

MIR16-2 (microRNA 16-2)

Atlas Genet Cytogenet Oncol Haematol. 2011-02-01

Online version: http://atlasgeneticsoncology.org/gene/52047/mir16-2