MIR181C (microRNA 181c)

2010-06-01  

Identity

HGNC
MIR181C
LOCATION
19p13.12
LOCUSID
406957
ALIAS
MIRN181C,mir-181c

Other Information

Locus ID:

NCBI: 406957
MIM: 612746
HGNC: 31552
Ensembl: ENSG00000207613
miRBase:

Variants:

dbSNP: 406957
ClinVar: 406957
TCGA: ENSG00000207613
COSMIC: MIR181C

RNA/Proteins

Expression (GTEx)

0
1
2
3
4
5
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
274284202016Exosome Derived From Human Umbilical Cord Mesenchymal Stem Cell Mediates MiR-181c Attenuating Burn-induced Excessive Inflammation.50
217207222012Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β.48
211120912011Human activated CD4(+) T lymphocytes increase IL-2 expression by downregulating microRNA-181c.24
247897932014Transcriptional suppression of miR-181c by hepatitis C virus enhances homeobox A1 expression.23
255352552015Modulation of TNF-α mRNA stability by human antigen R and miR181s in sepsis-induced immunoparalysis.23
243454802014MiR-181c modulates the proliferation, migration, and invasion of neuroblastoma cells by targeting Smad7.16
266829282016MicroRNA-181c inhibits glioblastoma cell invasion, migration and mesenchymal transition by targeting TGF-β pathway.15
269835742016Epigenetic silencing of miR-181c by DNA methylation in glioblastoma cell lines.14
275278562016Upregulation of miR-181c inhibits chemoresistance by targeting ST8SIA4 in chronic myelocytic leukemia.13
245736372014miR-181 subunits enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeleton remodeling in glioblastoma cells.11

Citation

Dessen P

MIR181C (microRNA 181c)

Atlas Genet Cytogenet Oncol Haematol. 2010-06-01

Online version: http://atlasgeneticsoncology.org/gene/51510/mir181c