MIR181D (microRNA 181d)

2014-06-01  

Identity

HGNC
MIR181D
LOCATION
19p13.12
LOCUSID
574457
ALIAS
MIRN181D,mir-181d

Other Information

Locus ID:

NCBI: 574457
HGNC: 32089
Ensembl: ENSG00000207585
miRBase:

Variants:

dbSNP: 574457
ClinVar: 574457
TCGA: ENSG00000207585
COSMIC: MIR181D

RNA/Proteins

Expression (GTEx)

0
1
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
222075242012MiR-181d acts as a tumor suppressor in glioma by targeting K-ras and Bcl-2.56
255352552015Modulation of TNF-α mRNA stability by human antigen R and miR181s in sepsis-induced immunoparalysis.23
282862602017miR-181d/MALT1 regulatory axis attenuates mesenchymal phenotype through NF-κB pathways in glioblastoma.16
287494702017miR-181d and c-myc-mediated inhibition of CRY2 and FBXL3 reprograms metabolism in colorectal cancer.13
245736372014miR-181 subunits enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeleton remodeling in glioblastoma cells.11
274471092016The miR-181d-regulated metalloproteinase Adamts1 enzymatically impairs adipogenesis via ECM remodeling.11
241037592013Thyroid hormone negatively regulates CDX2 and SOAT2 mRNA expression via induction of miRNA-181d in hepatic cells.10
269398692016Distinct miRNA profiles in normal and gastric cancer myofibroblasts and significance in Wnt signaling.6
275722702016MicroRNA-181d is a tumor suppressor in human esophageal squamous cell carcinoma inversely regulating Derlin-1.6
300316072018miR-181d-5p-FOXP1 feedback loop modulates the progression of osteosarcoma.4

Citation

Dessen P

MIR181D (microRNA 181d)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/53997/mir181d