MIR186 (microRNA 186)

2008-12-01  

Identity

HGNC
LOCATION
1p31.1
LOCUSID
ALIAS
MIRN186,miR-186

Other Information

Locus ID:

NCBI: 406962
HGNC: 31557
Ensembl: ENSG00000207721
miRBase:

Variants:

dbSNP: 406962
ClinVar: 406962
TCGA: ENSG00000207721
COSMIC: MIR186

RNA/Proteins

Expression (GTEx)

0
1
2

References

Pubmed IDYearTitleCitations
258670642016miR-186 regulation of Twist1 and ovarian cancer sensitivity to cisplatin.51
186823932008MicroRNAs miR-186 and miR-150 down-regulate expression of the pro-apoptotic purinergic P2X7 receptor by activation of instability sites at the 3'-untranslated region of the gene that decrease steady-state levels of the transcript.47
236711272013PTTG1 promotes migration and invasion of human non-small cell lung cancer cells and is modulated by miR-186.39
287652792017The long noncoding RNA HULC promotes liver cancer by increasing the expression of the HMGA2 oncogene via sequestration of the microRNA-186.33
285717412017Circular RNA hsa_circ_0010729 regulates vascular endothelial cell proliferation and apoptosis by targeting the miR-186/HIF-1α axis.31
294522322018Long noncoding RNA PVT1 promotes EMT via mediating microRNA-186 targeting of Twist1 in prostate cancer.28
248946762014MiR-186 targets ROCK1 to suppress the growth and metastasis of NSCLC cells.27
284489932017The Long Non-Coding RNA XIST Controls Non-Small Cell Lung Cancer Proliferation and Invasion by Modulating miR-186-5p.26
283024872017TUG1 mediates methotrexate resistance in colorectal cancer via miR-186/CPEB2 axis.25
286568792017Long non-coding RNA PVT1 serves as a competing endogenous RNA for miR-186-5p to promote the tumorigenesis and metastasis of hepatocellular carcinoma.25

Citation

Dessen P

MIR186 (microRNA 186)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50602/mir186