MIR206 (microRNA 206)

2008-09-01  

Identity

HGNC
LOCATION
6p12.2
LOCUSID
ALIAS
MIRN206,miRNA206,mir-206

Other Information

Locus ID:

NCBI: 406989
MIM: 611599
HGNC: 31584
Ensembl: ENSG00000207604
miRBase:

Variants:

dbSNP: 406989
ClinVar: 406989
TCGA: ENSG00000207604
COSMIC: MIR206

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
185938972008miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer.119
239211242013Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis.110
263251802015Down-regulation of c-Met and Bcl2 by microRNA-206, activates apoptosis, and inhibits tumor cell proliferation, migration and colony formation.53
215189592011A KLF4-miRNA-206 autoregulatory feedback loop can promote or inhibit protein translation depending upon cell context.52
255005422015MicroRNA-206 functions as a pleiotropic modulator of cell proliferation, invasion and lymphangiogenesis in pancreatic adenocarcinoma by targeting ANXA2 and KRAS genes.48
223303402012Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma.45
233486982013miR-206 inhibits gastric cancer proliferation in part by repressing cyclinD2.43
219831302012Expression of the tumor suppressor miR-206 is associated with cellular proliferative inhibition and impairs invasion in ERα-positive endometrioid adenocarcinoma.38
194236512009The role of miR-206 in the epidermal growth factor (EGF) induced repression of estrogen receptor-alpha (ERalpha) signaling and a luminal phenotype in MCF-7 breast cancer cells.36
203472652010MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia.34

Citation

Dessen P

MIR206 (microRNA 206)

Atlas Genet Cytogenet Oncol Haematol. 2008-09-01

Online version: http://atlasgeneticsoncology.org/gene/50341/mir206