MIR29A (microRNA 29a)

2008-12-01  

Identity

HGNC
LOCATION
7q32.3
LOCUSID
ALIAS
MIRN29,MIRN29A,hsa-mir-29,hsa-mir-29a,miRNA29A,mir-29a

Other Information

Locus ID:

NCBI: 407021
MIM: 610782
HGNC: 31616
Ensembl: ENSG00000284032
miRBase:

Variants:

dbSNP: 407021
ClinVar: 407021
TCGA: ENSG00000284032
COSMIC: MIR29A

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
184345502008Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression.400
216252152011microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer.231
205642132010Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB.122
200862452010microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma.118
230796602012Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-Cell lymphomas.106
216464252011miR-29a and miR-29b contribute to pancreatic beta-cell-specific silencing of monocarboxylate transporter 1 (Mct1).93
211874252011miR-29 and miR-30 regulate B-Myb expression during cellular senescence.82
210305532011Discovery of recurrent t(6;7)(p25.3;q32.3) translocations in ALK-negative anaplastic large cell lymphomas by massively parallel genomic sequencing.67
231003932012DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma.64
200677972010High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells.62

Citation

Dessen P

MIR29A (microRNA 29a)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50559/mir29a