MIR346 (microRNA 346)

2017-04-01  

Identity

HGNC
MIR346
LOCATION
10q23.2
LOCUSID
442911
ALIAS
MIRN346,hsa-mir-346,miR-346,miRNA346

Other Information

Locus ID:

NCBI: 442911
MIM: 611190
HGNC: 31780
Ensembl: ENSG00000199104
miRBase:

Variants:

dbSNP: 442911
ClinVar: 442911
TCGA: ENSG00000199104
COSMIC: MIR346

RNA/Proteins

References

Pubmed IDYearTitleCitations
220020582011The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genes.47
193426892009Bruton's tyrosine kinase is involved in miR-346-related regulation of IL-18 release by lipopolysaccharide-activated rheumatoid fibroblast-like synoviocytes.37
216111962011miR-346 controls release of TNF-α protein and stability of its mRNA in rheumatoid arthritis via tristetraprolin stabilization.34
300538672018circFBLIM1 act as a ceRNA to promote hepatocellular cancer progression by sponging miR-346.28
265074542015miR-346 and miR-138 competitively regulate hTERT in GRSF1- and AGO2-dependent manners, respectively.22
265188742015miR-346 Up-regulates Argonaute 2 (AGO2) Protein Expression to Augment the Activity of Other MicroRNAs (miRNAs) and Contributes to Cervical Cancer Cell Malignancy.21
279131852017MiR-346 promotes the biological function of breast cancer cells by targeting SRCIN1 and reduces chemosensitivity to docetaxel.13
302164422018LncRNA DGCR5 represses the development of hepatocellular carcinoma by targeting the miR-346/KLF14 axis.13
304707992019Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5'-untranslated region: Implications in Alzheimer's disease.12
256669352015MiR-346 regulates CD4⁺CXCR5⁺ T cells in the pathogenesis of Graves' disease.11

Citation

Dessen P

MIR346 (microRNA 346)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56786/mir346