MIR506 (microRNA 506)

2011-10-01  

Identity

HGNC
LOCATION
Xq27.3
LOCUSID
ALIAS
MIRN506,hsa-mir-506,mir-506

Other Information

Locus ID:

NCBI: 574511
MIM: 300877
HGNC: 32143
Ensembl: ENSG00000207731
miRBase:

Variants:

dbSNP: 574511
ClinVar: 574511
TCGA: ENSG00000207731
COSMIC: MIR506

RNA/Proteins

References

Pubmed IDYearTitleCitations
234109732013Integrated analyses identify a master microRNA regulatory network for the mesenchymal subtype in serous ovarian cancer.151
223831622012Up-regulation of microRNA 506 leads to decreased Cl-/HCO3- anion exchanger 2 expression in biliary epithelium of patients with primary biliary cirrhosis.55
246084272015miR-506 acts as a tumor suppressor by directly targeting the hedgehog pathway transcription factor Gli3 in human cervical cancer.49
270653352016Downregulated miR-506 expression facilitates pancreatic cancer progression and chemoresistance via SPHK1/Akt/NF-κB signaling.46
246041172014MiR-506 suppresses proliferation and induces senescence by directly targeting the CDK4/6-FOXM1 axis in ovarian cancer.42
244690512015Selective killing of lung cancer cells by miRNA-506 molecule through inhibiting NF-κB p65 to evoke reactive oxygen species generation and p53 activation.32
258467312015MicroRNA-506 inhibits gastric cancer proliferation and invasion by directly targeting Yap1.31
257933702015MiR-506 is down-regulated in clear cell renal cell carcinoma and inhibits cell growth and metastasis via targeting FLOT1.29
264521292015MicroRNA-506 suppresses tumor proliferation and metastasis in colon cancer by directly targeting the oncogene EZH2.29
250879982014MiR-506 suppresses proliferation of hepatoma cells through targeting YAP mRNA 3'UTR.19

Citation

Dessen P

MIR506 (microRNA 506)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52452/mir506