MIR7-2 (microRNA 7-2)

2013-07-01  

Identity

HGNC
LOCATION
15q26.1
LOCUSID
ALIAS
MIRN7-2,hsa-mir-7-2,mir-7-2

Other Information

Locus ID:

NCBI: 407044
HGNC: 31639
Ensembl: ENSG00000207703
miRBase:

Variants:

dbSNP: 407044
ClinVar: 407044
TCGA: ENSG00000207703
COSMIC: MIR7-2

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
231359982013MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway.37
255117422015miR-7-5p suppresses cell proliferation and induces apoptosis of breast cancer cells mainly by targeting REGγ.37
264539262015MicroRNA-7 activates Nrf2 pathway by targeting Keap1 expression.30
253944922014MicroRNA-7 directly targets insulin-like growth factor 1 receptor to inhibit cellular growth and glucose metabolism in gliomas.22
250274032014MiR-7-5p is frequently downregulated in glioblastoma microvasculature and inhibits vascular endothelial cell proliferation by targeting RAF1.18
227682382012A microRNA-7 binding site polymorphism in HOXB5 leads to differential gene expression in bladder cancer.16
261085392015miR-7 modulates chemoresistance of small cell lung cancer by repressing MRP1/ABCC1.15
26931423201617β-estradiol ameliorates age-associated loss of fibroblast function by attenuating IFN-γ/STAT1-dependent miR-7 upregulation.9
312154812019MiR-7-5p-mediated downregulation of PARP1 impacts DNA homologous recombination repair and resistance to doxorubicin in small cell lung cancer.8
268316662016MicroRNA-7 downregulates the oncogene VDAC1 to influence hepatocellular carcinoma proliferation and metastasis.6

Citation

Dessen P

MIR7-2 (microRNA 7-2)

Atlas Genet Cytogenet Oncol Haematol. 2013-07-01

Online version: http://atlasgeneticsoncology.org/gene/53448/mir7-2