MIRLET7I (microRNA let-7i)

2013-06-01  

Identity

HGNC
MIRLET7I
LOCATION
12q14.1
LOCUSID
406891
ALIAS
LET7I,MIRNLET7I,hsa-let-7i,let-7i

Other Information

Locus ID:

NCBI: 406891
MIM: 612148
HGNC: 31486
Ensembl: ENSG00000199179
miRBase:

Variants:

dbSNP: 406891
ClinVar: 406891
TCGA: ENSG00000199179
COSMIC: MIRLET7I

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
199038132010NFkappaB p50-CCAAT/enhancer-binding protein beta (C/EBPbeta)-mediated transcriptional repression of microRNA let-7i following microbial infection.45
246628292015A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis.32
222108952012Ectopic over-expression of tristetraprolin in human cancer cells promotes biogenesis of let-7 by down-regulation of Lin28.17
249429262014Interferon controls SUMO availability via the Lin28 and let-7 axis to impede virus replication.17
253054902014MicroRNA let-7i induced autophagy to protect T cell from apoptosis by targeting IGF1R.14
266552712016BAG3-mediated miRNA let-7g and let-7i inhibit proliferation and enhance apoptosis of human esophageal carcinoma cells by targeting the drug transporter ABCC10.13
256565722015MicroRNAs let-7b/i suppress human glioma cell invasion and migration by targeting IKBKE directly.12
234541232013Repression of bone morphogenetic protein 4 by let-7i attenuates mesenchymal migration of head and neck cancer cells.7
248629342014Cryptosporidium parvum induces SIRT1 expression in host epithelial cells through downregulating let-7i.7
280799732017A regulatory BMI1/let-7i/ERK3 pathway controls the motility of head and neck cancer cells.7

Citation

Dessen P

MIRLET7I (microRNA let-7i)

Atlas Genet Cytogenet Oncol Haematol. 2013-06-01

Online version: http://atlasgeneticsoncology.org/gene/53364/mirlet7i