MKNK2 (MAP kinase interacting serine/threonine kinase 2)

Identity

Other names	GPRK7
	MNK2
HGNC	MKNK2
Location	19p13.3
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	MKNK2   7111
Entrez_Gene	MKNK2  2872  MAP kinase interacting serine/threonine kinase 2
	Cards
GeneCards	MKNK2
Ensembl	MKNK2 [Search_View]   ENSG00000099875 [Gene_View]
Genatlas	MKNK2
GeneLynx	MKNK2
eGenome	MKNK2
euGene	2872
	Genomic and cartography
GoldenPath	MKNK2  -  19p13.3   chr19:1988470-2002243 -  19p13.3   [Description]    (hg18-March_2006)
Ensembl	MKNK2 - 19p13.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	MKNK2
	Gene and transcription
Genbank	AB209074 [ ENTREZ ]
Genbank	AF125532 [ ENTREZ ]
Genbank	AF237775 [ ENTREZ ]
Genbank	AF237776 [ ENTREZ ]
Genbank	AK001730 [ ENTREZ ]
RefSeq	NM_017572 [ SRS ]    NM_017572 [ ENTREZ ]
RefSeq	NM_199054 [ SRS ]    NM_199054 [ ENTREZ ]
RefSeq	AC_000062 [ SRS ]    AC_000062 [ ENTREZ ]
RefSeq	AC_000151 [ SRS ]    AC_000151 [ ENTREZ ]
RefSeq	NC_000019 [ SRS ]    NC_000019 [ ENTREZ ]
RefSeq	NT_011255 [ SRS ]    NT_011255 [ ENTREZ ]
RefSeq	NW_001838476 [ SRS ]    NW_001838476 [ ENTREZ ]
RefSeq	NW_927173 [ SRS ]    NW_927173 [ ENTREZ ]
AceView	MKNK2 AceView - NCBI
Unigene	Hs.515032 [ SRS ]    Hs.515032 [ NCBI ]     HS515032 [ spliceNest ]
Fast-db	1434 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q59GN5 [ SRS]    Q59GN5 [ EXPASY ]     Q59GN5 [ INTERPRO ]     Q59GN5 [ UNIPROT ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Interpro	IPR015731 MAP_k_interact_k [ SRS ]    IPR015731 MAP_k_interact_k [ EBI ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
CluSTr	Q59GN5
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	Q59GN5 Q59GN5_HUMAN [ Domain structure ]   Q59GN5 Q59GN5_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q59GN5
HPRD	05459
	Protein Interaction databases
DIP	Q59GN5
IntAct	Q59GN5
	Polymorphism : SNP, mutations, diseases
OMIM	605069    [ map ]
GENECLINICS	605069
SNP	MKNK2 [dbSNP-NCBI]
SNP	NM_017572 [SNP-NCI]
SNP	NM_199054 [SNP-NCI]
SNP	MKNK2 [GeneSNPs - Utah]  MKNK2] [HGBASE - SRS]
HAPMAP	MKNK2 [HAPMAP]
COSMIC	MKNK2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	MKNK2
	General knowledge
Family Browser	MKNK2 [UCSC Family Browser]
SOURCE	NM_017572
SOURCE	NM_199054
SMD	Hs.515032
SAGE	Hs.515032
GO	nucleotide binding [Amigo]  nucleotide binding
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	ATP binding [Amigo]  ATP binding
GO	ATP binding [Amigo]  ATP binding
GO	regulation of translation [Amigo]  regulation of translation
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	cell surface receptor linked signal transduction [Amigo]  cell surface receptor linked signal transduction
GO	protein kinase cascade [Amigo]  protein kinase cascade
GO	zinc ion binding [Amigo]  zinc ion binding
GO	transferase activity [Amigo]  transferase activity
BIOCARTA	Erk1/Erk2 Mapk Signaling pathway    [Genes]
BIOCARTA	MAPKinase Signaling Pathway    [Genes]
KEGG	MAPK signaling pathway
KEGG	Insulin signaling pathway
PubGene	MKNK2
TreeFam	MKNK2
CTD	2872 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	MKNK2 Related clones (RZPD - Berlin)
	PubMed
PubMed	16 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:20:24 2008