Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MKRN3 (makorin ring finger protein 3)

Identity

Alias_namesZNF127
D15S9
Alias_symbol (synonym)RNF63
ZFP127
MGC88288
Other aliasCPPB2
HGNC (Hugo) MKRN3
LocusID (NCBI) 7681
Atlas_Id 70331
Location 15q11.2  [Link to chromosome band 15q11]
Location_base_pair Starts at 23810454 and ends at 23813166 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MKRN3   7114
LRG (Locus Reference Genomic)LRG_1045
Cards
Entrez_Gene (NCBI)MKRN3  7681  makorin ring finger protein 3
AliasesCPPB2; D15S9; RNF63; ZFP127; 
ZNF127
GeneCards (Weizmann)MKRN3
Ensembl hg19 (Hinxton)ENSG00000179455 [Gene_View]  chr15:23810454-23813166 [Contig_View]  MKRN3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000179455 [Gene_View]  chr15:23810454-23813166 [Contig_View]  MKRN3 [Vega]
ICGC DataPortalENSG00000179455
TCGA cBioPortalMKRN3
AceView (NCBI)MKRN3
Genatlas (Paris)MKRN3
WikiGenes7681
SOURCE (Princeton)MKRN3
Genetics Home Reference (NIH)MKRN3
Genomic and cartography
GoldenPath hg19 (UCSC)MKRN3  -     chr15:23810454-23813166 +  15q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MKRN3  -     15q11.2   [Description]    (hg38-Dec_2013)
EnsemblMKRN3 - 15q11.2 [CytoView hg19]  MKRN3 - 15q11.2 [CytoView hg38]
Mapping of homologs : NCBIMKRN3 [Mapview hg19]  MKRN3 [Mapview hg38]
OMIM176270   603856   615346   
Gene and transcription
Genbank (Entrez)AI939624 AK309383 AW445166 BC044639 BC070293
RefSeq transcript (Entrez)NM_005664
RefSeq genomic (Entrez)NC_000015 NC_018926 NG_012875 NT_010194 NW_004929397
Consensus coding sequences : CCDS (NCBI)MKRN3
Cluster EST : UnigeneHs.679587 [ NCBI ]
CGAP (NCI)Hs.679587
Alternative Splicing GalleryENSG00000179455
Gene ExpressionMKRN3 [ NCBI-GEO ]   MKRN3 [ EBI - ARRAY_EXPRESS ]   MKRN3 [ SEEK ]   MKRN3 [ MEM ]
Gene Expression Viewer (FireBrowse)MKRN3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7681
GTEX Portal (Tissue expression)MKRN3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13064   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13064  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13064
Splice isoforms : SwissVarQ13064
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
PhosPhoSitePlusQ13064
Domaine pattern : Prosite (Expaxy)ZF_C3H1 (PS50103)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Makorin_3    Znf_C3HC4_RING-type    Znf_CCCH    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)zf-C3HC4 (PF00097)   
Domain families : Pfam (NCBI)pfam00097   
Domain families : Smart (EMBL)RING (SM00184)  ZnF_C3H1 (SM00356)  
Conserved Domain (NCBI)MKRN3
DMDM Disease mutations7681
Blocks (Seattle)MKRN3
SuperfamilyQ13064
Human Protein AtlasENSG00000179455
Peptide AtlasQ13064
HPRD04836
IPIIPI00024229   
Protein Interaction databases
DIP (DOE-UCLA)Q13064
IntAct (EBI)Q13064
FunCoupENSG00000179455
BioGRIDMKRN3
STRING (EMBL)MKRN3
ZODIACMKRN3
Ontologies - Pathways
QuickGOQ13064
Ontology : AmiGOprotein binding  zinc ion binding  protein ubiquitination  ligase activity  ribonucleoprotein complex  
Ontology : EGO-EBIprotein binding  zinc ion binding  protein ubiquitination  ligase activity  ribonucleoprotein complex  
NDEx NetworkMKRN3
Atlas of Cancer Signalling NetworkMKRN3
Wikipedia pathwaysMKRN3
Orthology - Evolution
OrthoDB7681
GeneTree (enSembl)ENSG00000179455
Phylogenetic Trees/Animal Genes : TreeFamMKRN3
HOVERGENQ13064
HOGENOMQ13064
Homologs : HomoloGeneMKRN3
Homology/Alignments : Family Browser (UCSC)MKRN3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMKRN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MKRN3
dbVarMKRN3
ClinVarMKRN3
1000_GenomesMKRN3 
Exome Variant ServerMKRN3
ExAC (Exome Aggregation Consortium)MKRN3 (select the gene name)
Genetic variants : HAPMAP7681
Genomic Variants (DGV)MKRN3 [DGVbeta]
DECIPHER (Syndromes)15:23810454-23813166  ENSG00000179455
CONAN: Copy Number AnalysisMKRN3 
Mutations
ICGC Data PortalMKRN3 
TCGA Data PortalMKRN3 
Broad Tumor PortalMKRN3
OASIS PortalMKRN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMKRN3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMKRN3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MKRN3
DgiDB (Drug Gene Interaction Database)MKRN3
DoCM (Curated mutations)MKRN3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MKRN3 (select a term)
intoGenMKRN3
Cancer3DMKRN3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176270    603856    615346   
Orphanet17866   
MedgenMKRN3
Genetic Testing Registry MKRN3
NextProtQ13064 [Medical]
TSGene7681
GENETestsMKRN3
Huge Navigator MKRN3 [HugePedia]
snp3D : Map Gene to Disease7681
BioCentury BCIQMKRN3
ClinGenMKRN3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7681
Chemical/Pharm GKB GenePA30833
Clinical trialMKRN3
Miscellaneous
canSAR (ICR)MKRN3 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMKRN3
EVEXMKRN3
GoPubMedMKRN3
iHOPMKRN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:33:18 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.