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MKX (mohawk homeobox)

Identity

Alias_namesC10orf48
IRXL1
chromosome 10 open reading frame 48
iroquois homeobox protein-like 1
Alias_symbol (synonym)MGC39616
Other aliasIFRX
HGNC (Hugo) MKX
LocusID (NCBI) 283078
Atlas_Id 55418
Location 10p12.1  [Link to chromosome band 10p12]
Location_base_pair Starts at 27672874 and ends at 27745849 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FAR2 (12p11.22) / MKX (10p12.1)MKX (10p12.1) / TGFB3 (14q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MKX   23729
Cards
Entrez_Gene (NCBI)MKX  283078  mohawk homeobox
AliasesC10orf48; IFRX; IRXL1
GeneCards (Weizmann)MKX
Ensembl hg19 (Hinxton)ENSG00000150051 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000150051 [Gene_View]  chr10:27672874-27745849 [Contig_View]  MKX [Vega]
ICGC DataPortalENSG00000150051
TCGA cBioPortalMKX
AceView (NCBI)MKX
Genatlas (Paris)MKX
WikiGenes283078
SOURCE (Princeton)MKX
Genetics Home Reference (NIH)MKX
Genomic and cartography
GoldenPath hg38 (UCSC)MKX  -     chr10:27672874-27745849 -  10p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MKX  -     10p12.1   [Description]    (hg19-Feb_2009)
EnsemblMKX - 10p12.1 [CytoView hg19]  MKX - 10p12.1 [CytoView hg38]
Mapping of homologs : NCBIMKX [Mapview hg19]  MKX [Mapview hg38]
OMIM601332   
Gene and transcription
Genbank (Entrez)AK125339 AW020078 BC036207 DB285243 HQ447218
RefSeq transcript (Entrez)NM_001242702 NM_173576
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MKX
Cluster EST : UnigeneHs.128193 [ NCBI ]
CGAP (NCI)Hs.128193
Alternative Splicing GalleryENSG00000150051
Gene ExpressionMKX [ NCBI-GEO ]   MKX [ EBI - ARRAY_EXPRESS ]   MKX [ SEEK ]   MKX [ MEM ]
Gene Expression Viewer (FireBrowse)MKX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)283078
GTEX Portal (Tissue expression)MKX
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IYA7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IYA7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IYA7
Splice isoforms : SwissVarQ8IYA7
PhosPhoSitePlusQ8IYA7
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Homeobox_KN_domain   
Domain families : Pfam (Sanger)Homeobox_KN (PF05920)   
Domain families : Pfam (NCBI)pfam05920   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)MKX
DMDM Disease mutations283078
Blocks (Seattle)MKX
SuperfamilyQ8IYA7
Human Protein AtlasENSG00000150051
Peptide AtlasQ8IYA7
HPRD12577
IPIIPI00217742   
Protein Interaction databases
DIP (DOE-UCLA)Q8IYA7
IntAct (EBI)Q8IYA7
FunCoupENSG00000150051
BioGRIDMKX
STRING (EMBL)MKX
ZODIACMKX
Ontologies - Pathways
QuickGOQ8IYA7
Ontology : AmiGOnucleus  regulation of transcription, DNA-templated  muscle organ development  sequence-specific DNA binding  
Ontology : EGO-EBInucleus  regulation of transcription, DNA-templated  muscle organ development  sequence-specific DNA binding  
NDEx NetworkMKX
Atlas of Cancer Signalling NetworkMKX
Wikipedia pathwaysMKX
Orthology - Evolution
OrthoDB283078
GeneTree (enSembl)ENSG00000150051
Phylogenetic Trees/Animal Genes : TreeFamMKX
HOVERGENQ8IYA7
HOGENOMQ8IYA7
Homologs : HomoloGeneMKX
Homology/Alignments : Family Browser (UCSC)MKX
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMKX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MKX
dbVarMKX
ClinVarMKX
1000_GenomesMKX 
Exome Variant ServerMKX
ExAC (Exome Aggregation Consortium)MKX (select the gene name)
Genetic variants : HAPMAP283078
Genomic Variants (DGV)MKX [DGVbeta]
DECIPHERMKX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMKX 
Mutations
ICGC Data PortalMKX 
TCGA Data PortalMKX 
Broad Tumor PortalMKX
OASIS PortalMKX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMKX  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMKX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MKX
DgiDB (Drug Gene Interaction Database)MKX
DoCM (Curated mutations)MKX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MKX (select a term)
intoGenMKX
Cancer3DMKX(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601332   
Orphanet
MedgenMKX
Genetic Testing Registry MKX
NextProtQ8IYA7 [Medical]
TSGene283078
GENETestsMKX
Target ValidationMKX
Huge Navigator MKX [HugePedia]
snp3D : Map Gene to Disease283078
BioCentury BCIQMKX
ClinGenMKX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD283078
Chemical/Pharm GKB GenePA134964449
Clinical trialMKX
Miscellaneous
canSAR (ICR)MKX (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMKX
EVEXMKX
GoPubMedMKX
iHOPMKX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:44:59 CEST 2017

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