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MKX (mohawk homeobox)

Identity

Alias (NCBI)C10orf48
IFRX
IRXL1
HGNC (Hugo) MKX
HGNC Alias symbMGC39616
HGNC Previous nameC10orf48
 IRXL1
HGNC Previous namechromosome 10 open reading frame 48
 iroquois homeobox protein-like 1
LocusID (NCBI) 283078
Atlas_Id 55418
Location 10p12.1  [Link to chromosome band 10p12]
Location_base_pair Starts at 27672874 and ends at 27745819 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FAR2 (12p11.22) / MKX (10p12.1)MKX (10p12.1) / TGFB3 (14q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MKX   23729
Cards
Entrez_Gene (NCBI)MKX    mohawk homeobox
AliasesC10orf48; IFRX; IRXL1
GeneCards (Weizmann)MKX
Ensembl hg19 (Hinxton)ENSG00000150051 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000150051 [Gene_View]  ENSG00000150051 [Sequence]  chr10:27672874-27745819 [Contig_View]  MKX [Vega]
ICGC DataPortalENSG00000150051
TCGA cBioPortalMKX
AceView (NCBI)MKX
Genatlas (Paris)MKX
SOURCE (Princeton)MKX
Genetics Home Reference (NIH)MKX
Genomic and cartography
GoldenPath hg38 (UCSC)MKX  -     chr10:27672874-27745819 -  10p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MKX  -     10p12.1   [Description]    (hg19-Feb_2009)
GoldenPathMKX - 10p12.1 [CytoView hg19]  MKX - 10p12.1 [CytoView hg38]
ImmunoBaseENSG00000150051
Genome Data Viewer NCBIMKX [Mapview hg19]  
OMIM601332   
Gene and transcription
Genbank (Entrez)AK125339 AW020078 BC036207 DB285243
RefSeq transcript (Entrez)NM_001242702 NM_173576
Consensus coding sequences : CCDS (NCBI)MKX
Gene ExpressionMKX [ NCBI-GEO ]   MKX [ EBI - ARRAY_EXPRESS ]   MKX [ SEEK ]   MKX [ MEM ]
Gene Expression Viewer (FireBrowse)MKX [ Firebrowse - Broad ]
GenevisibleExpression of MKX in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)283078
GTEX Portal (Tissue expression)MKX
Human Protein AtlasENSG00000150051-MKX [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IYA7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IYA7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IYA7
PhosPhoSitePlusQ8IYA7
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like_sf    Homeobox_CS    Homeobox_dom    Homeobox_KN_domain   
Domain families : Pfam (Sanger)Homeobox_KN (PF05920)   
Domain families : Pfam (NCBI)pfam05920   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)MKX
SuperfamilyQ8IYA7
AlphaFold pdb e-kbQ8IYA7   
Human Protein Atlas [tissue]ENSG00000150051-MKX [tissue]
HPRD12577
Protein Interaction databases
DIP (DOE-UCLA)Q8IYA7
IntAct (EBI)Q8IYA7
BioGRIDMKX
STRING (EMBL)MKX
ZODIACMKX
Ontologies - Pathways
QuickGOQ8IYA7
Ontology : AmiGOchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  nucleus  regulation of transcription by RNA polymerase II  muscle organ development  muscle organ development  cell development  
Ontology : EGO-EBIchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  nucleus  regulation of transcription by RNA polymerase II  muscle organ development  muscle organ development  cell development  
NDEx NetworkMKX
Atlas of Cancer Signalling NetworkMKX
Wikipedia pathwaysMKX
Orthology - Evolution
OrthoDB283078
GeneTree (enSembl)ENSG00000150051
Phylogenetic Trees/Animal Genes : TreeFamMKX
Homologs : HomoloGeneMKX
Homology/Alignments : Family Browser (UCSC)MKX
Gene fusions - Rearrangements
Fusion : QuiverMKX
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMKX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MKX
dbVarMKX
ClinVarMKX
MonarchMKX
1000_GenomesMKX 
Exome Variant ServerMKX
GNOMAD BrowserENSG00000150051
Varsome BrowserMKX
ACMGMKX variants
VarityQ8IYA7
Genomic Variants (DGV)MKX [DGVbeta]
DECIPHERMKX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMKX 
Mutations
ICGC Data PortalMKX 
TCGA Data PortalMKX 
Broad Tumor PortalMKX
OASIS PortalMKX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMKX  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMKX
Mutations and Diseases : HGMDMKX
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMKX
DgiDB (Drug Gene Interaction Database)MKX
DoCM (Curated mutations)MKX
CIViC (Clinical Interpretations of Variants in Cancer)MKX
Cancer3DMKX
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601332   
Orphanet
DisGeNETMKX
MedgenMKX
Genetic Testing Registry MKX
NextProtQ8IYA7 [Medical]
GENETestsMKX
Target ValidationMKX
Huge Navigator MKX [HugePedia]
ClinGenMKX
Clinical trials, drugs, therapy
MyCancerGenomeMKX
Protein Interactions : CTDMKX
Pharm GKB GenePA134964449
PharosQ8IYA7
Clinical trialMKX
Miscellaneous
canSAR (ICR)MKX
HarmonizomeMKX
DataMed IndexMKX
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMKX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:20:57 CEST 2021

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