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MLF2 (myeloid leukemia factor 2)

Identity

Alias_symbol (synonym)NTN4
Other alias
HGNC (Hugo) MLF2
LocusID (NCBI) 8079
Atlas_Id 41374
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 6747992 and ends at 6752916 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HDGFRP2 (19p13.3) / MLF2 (12p13.31)MLF2 (12p13.31) / MYOT (5q31.2)MLF2 (12p13.31) / OXNAD1 (3p25.1)
MLF2 (12p13.31) / PTMS (12p13.31)MLF2 (12p13.31) / TP53 (17p13.1)SLC25A37 (8p21.2) / MLF2 (12p13.31)
MLF2 12p13.31 / PTMS 12p13.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MLF2   7126
Cards
Entrez_Gene (NCBI)MLF2  8079  myeloid leukemia factor 2
AliasesNTN4
GeneCards (Weizmann)MLF2
Ensembl hg19 (Hinxton)ENSG00000089693 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000089693 [Gene_View]  chr12:6747992-6752916 [Contig_View]  MLF2 [Vega]
ICGC DataPortalENSG00000089693
TCGA cBioPortalMLF2
AceView (NCBI)MLF2
Genatlas (Paris)MLF2
WikiGenes8079
SOURCE (Princeton)MLF2
Genetics Home Reference (NIH)MLF2
Genomic and cartography
GoldenPath hg38 (UCSC)MLF2  -     chr12:6747992-6752916 -  12p13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MLF2  -     12p13.31   [Description]    (hg19-Feb_2009)
EnsemblMLF2 - 12p13.31 [CytoView hg19]  MLF2 - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBIMLF2 [Mapview hg19]  MLF2 [Mapview hg38]
OMIM601401   
Gene and transcription
Genbank (Entrez)AF070539 AK289869 AK313998 BC000898 BC002340
RefSeq transcript (Entrez)NM_005439
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MLF2
Cluster EST : UnigeneHs.524214 [ NCBI ]
CGAP (NCI)Hs.524214
Alternative Splicing GalleryENSG00000089693
Gene ExpressionMLF2 [ NCBI-GEO ]   MLF2 [ EBI - ARRAY_EXPRESS ]   MLF2 [ SEEK ]   MLF2 [ MEM ]
Gene Expression Viewer (FireBrowse)MLF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8079
GTEX Portal (Tissue expression)MLF2
Human Protein AtlasENSG00000089693-MLF2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15773   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15773  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15773
Splice isoforms : SwissVarQ15773
PhosPhoSitePlusQ15773
Domains : Interpro (EBI)Myeloid_leukemia_factor   
Domain families : Pfam (Sanger)Mlf1IP (PF10248)   
Domain families : Pfam (NCBI)pfam10248   
Conserved Domain (NCBI)MLF2
DMDM Disease mutations8079
Blocks (Seattle)MLF2
SuperfamilyQ15773
Human Protein Atlas [tissue]ENSG00000089693-MLF2 [tissue]
Peptide AtlasQ15773
HPRD03238
IPIIPI00023095   IPI01010157   IPI01009640   IPI01015291   
Protein Interaction databases
DIP (DOE-UCLA)Q15773
IntAct (EBI)Q15773
FunCoupENSG00000089693
BioGRIDMLF2
STRING (EMBL)MLF2
ZODIACMLF2
Ontologies - Pathways
QuickGOQ15773
Ontology : AmiGOprotein binding  nucleus  cytoplasm  defense response  membrane  
Ontology : EGO-EBIprotein binding  nucleus  cytoplasm  defense response  membrane  
NDEx NetworkMLF2
Atlas of Cancer Signalling NetworkMLF2
Wikipedia pathwaysMLF2
Orthology - Evolution
OrthoDB8079
GeneTree (enSembl)ENSG00000089693
Phylogenetic Trees/Animal Genes : TreeFamMLF2
HOVERGENQ15773
HOGENOMQ15773
Homologs : HomoloGeneMLF2
Homology/Alignments : Family Browser (UCSC)MLF2
Gene fusions - Rearrangements
Fusion : MitelmanMLF2/PTMS [12p13.31/12p13.31]  
Fusion: TCGA_MDACCMLF2 12p13.31 PTMS 12p13.31 BRCA
Tumor Fusion PortalMLF2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMLF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MLF2
dbVarMLF2
ClinVarMLF2
1000_GenomesMLF2 
Exome Variant ServerMLF2
ExAC (Exome Aggregation Consortium)ENSG00000089693
GNOMAD BrowserENSG00000089693
Genetic variants : HAPMAP8079
Genomic Variants (DGV)MLF2 [DGVbeta]
DECIPHERMLF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMLF2 
Mutations
ICGC Data PortalMLF2 
TCGA Data PortalMLF2 
Broad Tumor PortalMLF2
OASIS PortalMLF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMLF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMLF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MLF2
DgiDB (Drug Gene Interaction Database)MLF2
DoCM (Curated mutations)MLF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MLF2 (select a term)
intoGenMLF2
Cancer3DMLF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601401   
Orphanet
DisGeNETMLF2
MedgenMLF2
Genetic Testing Registry MLF2
NextProtQ15773 [Medical]
TSGene8079
GENETestsMLF2
Target ValidationMLF2
Huge Navigator MLF2 [HugePedia]
snp3D : Map Gene to Disease8079
BioCentury BCIQMLF2
ClinGenMLF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8079
Chemical/Pharm GKB GenePA30844
Clinical trialMLF2
Miscellaneous
canSAR (ICR)MLF2 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMLF2
EVEXMLF2
GoPubMedMLF2
iHOPMLF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:24:27 CET 2017

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