Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MLXIP (MLX interacting protein)

Identity

Alias (NCBI)MIR
MONDOA
bHLHe36
HGNC (Hugo) MLXIP
HGNC Alias symbMONDOA
KIAA0867
MIR
bHLHe36
LocusID (NCBI) 22877
Atlas_Id 52918
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 122078756 and ends at 122147342 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACRBP (12p13.31) / MLXIP (12q24.31)GRAP2 (22q13.1) / MLXIP (12q24.31)KNTC1 (12q24.31) / MLXIP (12q24.31)
PTGES2 (9q34.11) / MLXIP (12q24.31)YY1AP1 (1q22) / MLXIP (12q24.31)KNTC1 12q24.31 / MLXIP 12q24.31
PTGES2 9q34.11 / MLXIP 12q24.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)MLXIP   17055
Cards
Entrez_Gene (NCBI)MLXIP    MLX interacting protein
AliasesMIR; MONDOA; bHLHe36
GeneCards (Weizmann)MLXIP
Ensembl hg19 (Hinxton)ENSG00000175727 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175727 [Gene_View]  ENSG00000175727 [Sequence]  chr12:122078756-122147342 [Contig_View]  MLXIP [Vega]
ICGC DataPortalENSG00000175727
TCGA cBioPortalMLXIP
AceView (NCBI)MLXIP
Genatlas (Paris)MLXIP
SOURCE (Princeton)MLXIP
Genetics Home Reference (NIH)MLXIP
Genomic and cartography
GoldenPath hg38 (UCSC)MLXIP  -     chr12:122078756-122147342 +  12q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MLXIP  -     12q24.31   [Description]    (hg19-Feb_2009)
GoldenPathMLXIP - 12q24.31 [CytoView hg19]  MLXIP - 12q24.31 [CytoView hg38]
ImmunoBaseENSG00000175727
genome Data Viewer NCBIMLXIP [Mapview hg19]  
OMIM608090   
Gene and transcription
Genbank (Entrez)AB020674 AF245480 AF245481 AF312918 AW996647
RefSeq transcript (Entrez)NM_014938
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MLXIP
Alternative Splicing GalleryENSG00000175727
Gene ExpressionMLXIP [ NCBI-GEO ]   MLXIP [ EBI - ARRAY_EXPRESS ]   MLXIP [ SEEK ]   MLXIP [ MEM ]
Gene Expression Viewer (FireBrowse)MLXIP [ Firebrowse - Broad ]
GenevisibleExpression of MLXIP in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22877
GTEX Portal (Tissue expression)MLXIP
Human Protein AtlasENSG00000175727-MLXIP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HAP2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HAP2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HAP2
Splice isoforms : SwissVarQ9HAP2
PhosPhoSitePlusQ9HAP2
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom    HLH_DNA-bd_sf    MLXIP   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)MLXIP
Blocks (Seattle)MLXIP
SuperfamilyQ9HAP2
Human Protein Atlas [tissue]ENSG00000175727-MLXIP [tissue]
Peptide AtlasQ9HAP2
HPRD10478
IPIIPI00102118   IPI00795813   IPI00797501   IPI00796815   IPI00382754   IPI01011688   IPI01018626   IPI01014277   IPI01014664   IPI01013476   
Protein Interaction databases
DIP (DOE-UCLA)Q9HAP2
IntAct (EBI)Q9HAP2
BioGRIDMLXIP
STRING (EMBL)MLXIP
ZODIACMLXIP
Ontologies - Pathways
QuickGOQ9HAP2
Ontology : AmiGOchromatin  RNA polymerase II transcription regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  nucleus  mitochondrial outer membrane  regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  protein dimerization activity  
Ontology : EGO-EBIchromatin  RNA polymerase II transcription regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  nucleus  mitochondrial outer membrane  regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  protein dimerization activity  
Pathways : KEGGNon-alcoholic fatty liver disease (NAFLD)   
NDEx NetworkMLXIP
Atlas of Cancer Signalling NetworkMLXIP
Wikipedia pathwaysMLXIP
Orthology - Evolution
OrthoDB22877
GeneTree (enSembl)ENSG00000175727
Phylogenetic Trees/Animal Genes : TreeFamMLXIP
HOGENOMQ9HAP2
Homologs : HomoloGeneMLXIP
Homology/Alignments : Family Browser (UCSC)MLXIP
Gene fusions - Rearrangements
Fusion : MitelmanKNTC1/MLXIP [12q24.31/12q24.31]  
Fusion : MitelmanPTGES2/MLXIP [9q34.11/12q24.31]  
Fusion PortalKNTC1 12q24.31 MLXIP 12q24.31 LUSC
Fusion PortalPTGES2 9q34.11 MLXIP 12q24.31 BLCA
Fusion : QuiverMLXIP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMLXIP [hg38]
dbVarMLXIP
ClinVarMLXIP
MonarchMLXIP
1000_GenomesMLXIP 
Exome Variant ServerMLXIP
GNOMAD BrowserENSG00000175727
Varsome BrowserMLXIP
Genomic Variants (DGV)MLXIP [DGVbeta]
DECIPHERMLXIP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMLXIP 
Mutations
ICGC Data PortalMLXIP 
TCGA Data PortalMLXIP 
Broad Tumor PortalMLXIP
OASIS PortalMLXIP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMLXIP  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMLXIP
Mutations and Diseases : HGMDMLXIP
BioMutasearch MLXIP
DgiDB (Drug Gene Interaction Database)MLXIP
DoCM (Curated mutations)MLXIP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MLXIP (select a term)
intoGenMLXIP
Cancer3DMLXIP(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608090   
Orphanet
DisGeNETMLXIP
MedgenMLXIP
Genetic Testing Registry MLXIP
NextProtQ9HAP2 [Medical]
GENETestsMLXIP
Target ValidationMLXIP
Huge Navigator MLXIP [HugePedia]
ClinGenMLXIP
Clinical trials, drugs, therapy
MyCancerGenomeMLXIP
Protein Interactions : CTD
Pharm GKB GenePA128394590
PharosQ9HAP2
Clinical trialMLXIP
Miscellaneous
canSAR (ICR)MLXIP (select the gene name)
HarmonizomeMLXIP
DataMed IndexMLXIP
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMLXIP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:34:29 CET 2021

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