Identity
HGNC
LOCATION
12q24.31
LOCUSID
ALIAS
MIR,MONDOA,bHLHe36
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22877
MIM: 608090
HGNC: 17055
Ensembl: ENSG00000175727
Variants:
dbSNP: 22877
ClinVar: 22877
TCGA: ENSG00000175727
COSMIC: MLXIP
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Non-alcoholic fatty liver disease (NAFLD) | KEGG | hsa04932 |
| Non-alcoholic fatty liver disease (NAFLD) | KEGG | ko04932 |
| Insulin resistance | KEGG | hsa04931 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33908607 | 2022 | MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress. | 6 |
| 33908607 | 2022 | MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress. | 6 |
| 33901495 | 2021 | MondoA-Thioredoxin-Interacting Protein Axis Maintains Regulatory T-Cell Identity and Function in Colorectal Cancer Microenvironment. | 42 |
| 33901495 | 2021 | MondoA-Thioredoxin-Interacting Protein Axis Maintains Regulatory T-Cell Identity and Function in Colorectal Cancer Microenvironment. | 42 |
| 31782782 | 2020 | TXNIP induced by MondoA, rather than ChREBP, suppresses cervical cancer cell proliferation, migration and invasion. | 14 |
| 31782782 | 2020 | TXNIP induced by MondoA, rather than ChREBP, suppresses cervical cancer cell proliferation, migration and invasion. | 14 |
| 30717828 | 2019 | Cellular acidosis triggers human MondoA transcriptional activity by driving mitochondrial ATP production. | 28 |
| 31287806 | 2019 | MondoA drives muscle lipid accumulation and insulin resistance. | 21 |
| 30717828 | 2019 | Cellular acidosis triggers human MondoA transcriptional activity by driving mitochondrial ATP production. | 28 |
| 31287806 | 2019 | MondoA drives muscle lipid accumulation and insulin resistance. | 21 |
| 29282201 | 2018 | MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells. | 28 |
| 29282201 | 2018 | MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells. | 28 |
| 26910886 | 2016 | Contrasting Patterns in the Evolution of Vertebrate MLX Interacting Protein (MLXIP) and MLX Interacting Protein-Like (MLXIPL) Genes. | 3 |
| 27500491 | 2016 | MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling. | 35 |
| 26910886 | 2016 | Contrasting Patterns in the Evolution of Vertebrate MLX Interacting Protein (MLXIP) and MLX Interacting Protein-Like (MLXIPL) Genes. | 3 |
Citation
Dessen P
MLXIP (MLX interacting protein)
Atlas Genet Cytogenet Oncol Haematol. 2012-10-01
Online version: http://atlasgeneticsoncology.org/gene/52918/mlxip
