Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MLXIP (MLX interacting protein)

Identity

Alias_symbol (synonym)MONDOA
KIAA0867
MIR
bHLHe36
Other alias
HGNC (Hugo) MLXIP
LocusID (NCBI) 22877
Atlas_Id 52918
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 122078728 and ends at 122147347 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACRBP (12p13.31) / MLXIP (12q24.31)GRAP2 (22q13.1) / MLXIP (12q24.31)KNTC1 (12q24.31) / MLXIP (12q24.31)
PTGES2 (9q34.11) / MLXIP (12q24.31)YY1AP1 (1q22) / MLXIP (12q24.31)KNTC1 12q24.31 / MLXIP 12q24.31
PTGES2 9q34.11 / MLXIP 12q24.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MLXIP   17055
Cards
Entrez_Gene (NCBI)MLXIP  22877  MLX interacting protein
AliasesMIR; MONDOA; bHLHe36
GeneCards (Weizmann)MLXIP
Ensembl hg19 (Hinxton)ENSG00000175727 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175727 [Gene_View]  chr12:122078728-122147347 [Contig_View]  MLXIP [Vega]
ICGC DataPortalENSG00000175727
TCGA cBioPortalMLXIP
AceView (NCBI)MLXIP
Genatlas (Paris)MLXIP
WikiGenes22877
SOURCE (Princeton)MLXIP
Genetics Home Reference (NIH)MLXIP
Genomic and cartography
GoldenPath hg38 (UCSC)MLXIP  -     chr12:122078728-122147347 +  12q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MLXIP  -     12q24.31   [Description]    (hg19-Feb_2009)
EnsemblMLXIP - 12q24.31 [CytoView hg19]  MLXIP - 12q24.31 [CytoView hg38]
Mapping of homologs : NCBIMLXIP [Mapview hg19]  MLXIP [Mapview hg38]
OMIM608090   
Gene and transcription
Genbank (Entrez)AB020674 AF245480 AF245481 AF312918 AW996647
RefSeq transcript (Entrez)NM_014938
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MLXIP
Cluster EST : UnigeneHs.731847 [ NCBI ]
CGAP (NCI)Hs.731847
Alternative Splicing GalleryENSG00000175727
Gene ExpressionMLXIP [ NCBI-GEO ]   MLXIP [ EBI - ARRAY_EXPRESS ]   MLXIP [ SEEK ]   MLXIP [ MEM ]
Gene Expression Viewer (FireBrowse)MLXIP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22877
GTEX Portal (Tissue expression)MLXIP
Human Protein AtlasENSG00000175727-MLXIP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HAP2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HAP2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HAP2
Splice isoforms : SwissVarQ9HAP2
PhosPhoSitePlusQ9HAP2
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom    MLXIP   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)MLXIP
DMDM Disease mutations22877
Blocks (Seattle)MLXIP
SuperfamilyQ9HAP2
Human Protein Atlas [tissue]ENSG00000175727-MLXIP [tissue]
Peptide AtlasQ9HAP2
HPRD10478
IPIIPI00102118   IPI00795813   IPI00797501   IPI00796815   IPI00382754   IPI01011688   IPI01018626   IPI01014277   IPI01014664   IPI01013476   
Protein Interaction databases
DIP (DOE-UCLA)Q9HAP2
IntAct (EBI)Q9HAP2
FunCoupENSG00000175727
BioGRIDMLXIP
STRING (EMBL)MLXIP
ZODIACMLXIP
Ontologies - Pathways
QuickGOQ9HAP2
Ontology : AmiGOtranscription factor activity, transcription factor binding  DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  mitochondrial outer membrane  transcription, DNA-templated  protein dimerization activity  regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter  
Ontology : EGO-EBItranscription factor activity, transcription factor binding  DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  mitochondrial outer membrane  transcription, DNA-templated  protein dimerization activity  regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter  
Pathways : KEGGNon-alcoholic fatty liver disease (NAFLD)   
NDEx NetworkMLXIP
Atlas of Cancer Signalling NetworkMLXIP
Wikipedia pathwaysMLXIP
Orthology - Evolution
OrthoDB22877
GeneTree (enSembl)ENSG00000175727
Phylogenetic Trees/Animal Genes : TreeFamMLXIP
HOVERGENQ9HAP2
HOGENOMQ9HAP2
Homologs : HomoloGeneMLXIP
Homology/Alignments : Family Browser (UCSC)MLXIP
Gene fusions - Rearrangements
Fusion : MitelmanKNTC1/MLXIP [12q24.31/12q24.31]  [t(12;12)(q24;q24)]  
Fusion : MitelmanPTGES2/MLXIP [9q34.11/12q24.31]  [t(9;12)(q34;q24)]  
Fusion: TCGA_MDACCKNTC1 12q24.31 MLXIP 12q24.31 LUSC
Fusion: TCGA_MDACCPTGES2 9q34.11 MLXIP 12q24.31 BLCA
Tumor Fusion PortalMLXIP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMLXIP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MLXIP
dbVarMLXIP
ClinVarMLXIP
1000_GenomesMLXIP 
Exome Variant ServerMLXIP
ExAC (Exome Aggregation Consortium)ENSG00000175727
GNOMAD BrowserENSG00000175727
Genetic variants : HAPMAP22877
Genomic Variants (DGV)MLXIP [DGVbeta]
DECIPHERMLXIP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMLXIP 
Mutations
ICGC Data PortalMLXIP 
TCGA Data PortalMLXIP 
Broad Tumor PortalMLXIP
OASIS PortalMLXIP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMLXIP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMLXIP
BioMutasearch MLXIP
DgiDB (Drug Gene Interaction Database)MLXIP
DoCM (Curated mutations)MLXIP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MLXIP (select a term)
intoGenMLXIP
Cancer3DMLXIP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608090   
Orphanet
DisGeNETMLXIP
MedgenMLXIP
Genetic Testing Registry MLXIP
NextProtQ9HAP2 [Medical]
TSGene22877
GENETestsMLXIP
Target ValidationMLXIP
Huge Navigator MLXIP [HugePedia]
snp3D : Map Gene to Disease22877
BioCentury BCIQMLXIP
ClinGenMLXIP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22877
Chemical/Pharm GKB GenePA128394590
Clinical trialMLXIP
Miscellaneous
canSAR (ICR)MLXIP (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMLXIP
EVEXMLXIP
GoPubMedMLXIP
iHOPMLXIP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:24:29 CET 2017

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