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MLYCD (malonyl-CoA decarboxylase)

Identity

Alias_symbol (synonym)MCD
hMCD
Other alias
HGNC (Hugo) MLYCD
LocusID (NCBI) 23417
Atlas_Id 54463
Location 16q23.3  [Link to chromosome band 16q23]
Location_base_pair Starts at 83932730 and ends at 83949787 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CDH13 (16q23.3) / MLYCD (16q23.3)MLYCD (16q23.3) / MGRN1 (16p13.3)MLYCD (16q23.3) / MLYCD (16q23.3)
MLYCD (16q23.3) / OSGIN1 (16q23.3)MLYCD 16q23.3 / MGRN1 16p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MLYCD   7150
Cards
Entrez_Gene (NCBI)MLYCD  23417  malonyl-CoA decarboxylase
AliasesMCD
GeneCards (Weizmann)MLYCD
Ensembl hg19 (Hinxton)ENSG00000103150 [Gene_View]  chr16:83932730-83949787 [Contig_View]  MLYCD [Vega]
Ensembl hg38 (Hinxton)ENSG00000103150 [Gene_View]  chr16:83932730-83949787 [Contig_View]  MLYCD [Vega]
ICGC DataPortalENSG00000103150
TCGA cBioPortalMLYCD
AceView (NCBI)MLYCD
Genatlas (Paris)MLYCD
WikiGenes23417
SOURCE (Princeton)MLYCD
Genetics Home Reference (NIH)MLYCD
Genomic and cartography
GoldenPath hg19 (UCSC)MLYCD  -     chr16:83932730-83949787 +  16q23.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MLYCD  -     16q23.3   [Description]    (hg38-Dec_2013)
EnsemblMLYCD - 16q23.3 [CytoView hg19]  MLYCD - 16q23.3 [CytoView hg38]
Mapping of homologs : NCBIMLYCD [Mapview hg19]  MLYCD [Mapview hg38]
OMIM248360   606761   
Gene and transcription
Genbank (Entrez)AF090834 AF097832 AF153679 AK094095 BC000286
RefSeq transcript (Entrez)NM_012213
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_009079 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)MLYCD
Cluster EST : UnigeneHs.644610 [ NCBI ]
CGAP (NCI)Hs.644610
Alternative Splicing GalleryENSG00000103150
Gene ExpressionMLYCD [ NCBI-GEO ]   MLYCD [ EBI - ARRAY_EXPRESS ]   MLYCD [ SEEK ]   MLYCD [ MEM ]
Gene Expression Viewer (FireBrowse)MLYCD [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23417
GTEX Portal (Tissue expression)MLYCD
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95822   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95822  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95822
Splice isoforms : SwissVarO95822
Catalytic activity : Enzyme4.1.1.9 [ Enzyme-Expasy ]   4.1.1.94.1.1.9 [ IntEnz-EBI ]   4.1.1.9 [ BRENDA ]   4.1.1.9 [ KEGG ]   
PhosPhoSitePlusO95822
Domains : Interpro (EBI)Malonyl_CoA_deC   
Domain families : Pfam (Sanger)MCD (PF05292)   
Domain families : Pfam (NCBI)pfam05292   
Conserved Domain (NCBI)MLYCD
DMDM Disease mutations23417
Blocks (Seattle)MLYCD
PDB (SRS)2YGW    4F0X   
PDB (PDBSum)2YGW    4F0X   
PDB (IMB)2YGW    4F0X   
PDB (RSDB)2YGW    4F0X   
Structural Biology KnowledgeBase2YGW    4F0X   
SCOP (Structural Classification of Proteins)2YGW    4F0X   
CATH (Classification of proteins structures)2YGW    4F0X   
SuperfamilyO95822
Human Protein AtlasENSG00000103150
Peptide AtlasO95822
HPRD05999
IPIIPI00000663   IPI00759655   
Protein Interaction databases
DIP (DOE-UCLA)O95822
IntAct (EBI)O95822
FunCoupENSG00000103150
BioGRIDMLYCD
STRING (EMBL)MLYCD
ZODIACMLYCD
Ontologies - Pathways
QuickGOO95822
Ontology : AmiGOresponse to ischemia  receptor binding  cytoplasm  mitochondrion  mitochondrial matrix  peroxisome  peroxisomal matrix  peroxisomal matrix  acetyl-CoA biosynthetic process  acetyl-CoA biosynthetic process  fatty acid biosynthetic process  acyl-CoA metabolic process  regulation of glucose metabolic process  positive regulation of fatty acid oxidation  malonyl-CoA decarboxylase activity  malonyl-CoA decarboxylase activity  malonyl-CoA catabolic process  
Ontology : EGO-EBIresponse to ischemia  receptor binding  cytoplasm  mitochondrion  mitochondrial matrix  peroxisome  peroxisomal matrix  peroxisomal matrix  acetyl-CoA biosynthetic process  acetyl-CoA biosynthetic process  fatty acid biosynthetic process  acyl-CoA metabolic process  regulation of glucose metabolic process  positive regulation of fatty acid oxidation  malonyl-CoA decarboxylase activity  malonyl-CoA decarboxylase activity  malonyl-CoA catabolic process  
Pathways : KEGGbeta-Alanine metabolism    Propanoate metabolism    Peroxisome   
NDEx NetworkMLYCD
Atlas of Cancer Signalling NetworkMLYCD
Wikipedia pathwaysMLYCD
Orthology - Evolution
OrthoDB23417
GeneTree (enSembl)ENSG00000103150
Phylogenetic Trees/Animal Genes : TreeFamMLYCD
HOVERGENO95822
HOGENOMO95822
Homologs : HomoloGeneMLYCD
Homology/Alignments : Family Browser (UCSC)MLYCD
Gene fusions - Rearrangements
Fusion : MitelmanCDH13/MLYCD [16q23.3/16q23.3]  [t(16;16)(q23;q23)]  
Fusion : MitelmanMLYCD/MGRN1 [16q23.3/16p13.3]  [t(16;16)(p13;q23)]  
Fusion: TCGAMLYCD 16q23.3 MGRN1 16p13.3 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMLYCD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MLYCD
dbVarMLYCD
ClinVarMLYCD
1000_GenomesMLYCD 
Exome Variant ServerMLYCD
ExAC (Exome Aggregation Consortium)MLYCD (select the gene name)
Genetic variants : HAPMAP23417
Genomic Variants (DGV)MLYCD [DGVbeta]
DECIPHER (Syndromes)16:83932730-83949787  ENSG00000103150
CONAN: Copy Number AnalysisMLYCD 
Mutations
ICGC Data PortalMLYCD 
TCGA Data PortalMLYCD 
Broad Tumor PortalMLYCD
OASIS PortalMLYCD [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMLYCD  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMLYCD
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MLYCD
DgiDB (Drug Gene Interaction Database)MLYCD
DoCM (Curated mutations)MLYCD (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MLYCD (select a term)
intoGenMLYCD
Cancer3DMLYCD(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM248360    606761   
Orphanet3295   
MedgenMLYCD
Genetic Testing Registry MLYCD
NextProtO95822 [Medical]
TSGene23417
GENETestsMLYCD
Huge Navigator MLYCD [HugePedia]
snp3D : Map Gene to Disease23417
BioCentury BCIQMLYCD
ClinGenMLYCD
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23417
Chemical/Pharm GKB GenePA30861
Clinical trialMLYCD
Miscellaneous
canSAR (ICR)MLYCD (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMLYCD
EVEXMLYCD
GoPubMedMLYCD
iHOPMLYCD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 13:17:06 CET 2017

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