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MMP10 (matrix metallopeptidase 10 (stromelysin 2))

Identity

Other namesSL-2
STMY2
HGNC (Hugo) MMP10
LocusID (NCBI) 4319
Location 11q22.2
Location_base_pair Starts at 102641233 and ends at 102651359 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MMP10   7156
Cards
Entrez_Gene (NCBI)MMP10  4319  matrix metallopeptidase 10 (stromelysin 2)
GeneCards (Weizmann)MMP10
Ensembl (Hinxton)ENSG00000166670 [Gene_View]  chr11:102641233-102651359 [Contig_View]  MMP10 [Vega]
AceView (NCBI)MMP10
Genatlas (Paris)MMP10
WikiGenes4319
SOURCE (Princeton)NM_002425
Genomic and cartography
GoldenPath (UCSC)MMP10  -  11q22.2   chr11:102641233-102651359 -  11q22.2   [Description]    (hg19-Feb_2009)
EnsemblMMP10 - 11q22.2 [CytoView]
Mapping of homologs : NCBIMMP10 [Mapview]
OMIM185260   
Gene and transcription
Genbank (Entrez)AK222601 AK313960 BC002591 BT007442 DQ891931
RefSeq transcript (Entrez)NM_002425
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NT_033899 NW_001838042 NW_004929381
Consensus coding sequences : CCDS (NCBI)MMP10
Cluster EST : UnigeneHs.2258 [ NCBI ]
CGAP (NCI)Hs.2258
Alternative Splicing : Fast-db (Paris)GSHG0006128
Alternative Splicing GalleryENSG00000166670
Gene ExpressionMMP10 [ NCBI-GEO ]     MMP10 [ SEEK ]   MMP10 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09238 (Uniprot)
NextProtP09238  [Medical]
With graphics : InterProP09238
Splice isoforms : SwissVarP09238 (Swissvar)
Catalytic activity : Enzyme3.4.24.22 [ Enzyme-Expasy ]   3.4.24.223.4.24.22 [ IntEnz-EBI ]   3.4.24.22 [ BRENDA ]   3.4.24.22 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)CYSTEINE_SWITCH (PS00546)    HEMOPEXIN (PS00024)    HEMOPEXIN_2 (PS51642)    ZINC_PROTEASE (PS00142)   
Domains : Interpro (EBI)Hemopexin-like_dom    Hemopexin-like_repeat    Hemopexin_CS    MetalloPept_cat_dom    Pept_M10_metallopeptidase    Pept_M10A    Pept_M10A_Metazoans    Pept_M10A_Zn_BS    Peptidase_Metallo    Peptidoglycan-bd-like   
Related proteins : CluSTrP09238
Domain families : Pfam (Sanger)Hemopexin (PF00045)    Peptidase_M10 (PF00413)    PG_binding_1 (PF01471)   
Domain families : Pfam (NCBI)pfam00045    pfam00413    pfam01471   
Domain families : Smart (EMBL)HX (SM00120)  ZnMc (SM00235)  
DMDM Disease mutations4319
Blocks (Seattle)P09238
PDB (SRS)1Q3A    3V96   
PDB (PDBSum)1Q3A    3V96   
PDB (IMB)1Q3A    3V96   
PDB (RSDB)1Q3A    3V96   
Human Protein AtlasENSG00000166670
Peptide AtlasP09238
HPRD01704
IPIIPI00013405   IPI01012130   
Protein Interaction databases
DIP (DOE-UCLA)P09238
IntAct (EBI)P09238
FunCoupENSG00000166670
BioGRIDMMP10
InParanoidP09238
Interologous Interaction database P09238
IntegromeDBMMP10
STRING (EMBL)MMP10
Ontologies - Pathways
Ontology : AmiGOmetalloendopeptidase activity  calcium ion binding  extracellular region  proteinaceous extracellular matrix  extracellular space  proteolysis  zinc ion binding  extracellular matrix disassembly  extracellular matrix organization  regulation of cell migration  collagen catabolic process  
Ontology : EGO-EBImetalloendopeptidase activity  calcium ion binding  extracellular region  proteinaceous extracellular matrix  extracellular space  proteolysis  zinc ion binding  extracellular matrix disassembly  extracellular matrix organization  regulation of cell migration  collagen catabolic process  
REACTOMEMMP10
Protein Interaction DatabaseMMP10
Wikipedia pathwaysMMP10
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)MMP10
SNP (GeneSNP Utah)MMP10
SNP : HGBaseMMP10
Genetic variants : HAPMAPMMP10
1000_GenomesMMP10 
ICGC programENSG00000166670 
Somatic Mutations in Cancer : COSMICMMP10 
CONAN: Copy Number AnalysisMMP10 
Mutations and Diseases : HGMDMMP10
OMIM185260   
GENETestsMMP10
Disease Genetic AssociationMMP10
Huge Navigator MMP10 [HugePedia]  MMP10 [HugeCancerGEM]
Genomic VariantsMMP10  MMP10 [DGVbeta]
Exome VariantMMP10
dbVarMMP10
ClinVarMMP10
snp3D : Map Gene to Disease4319
General knowledge
Homologs : HomoloGeneMMP10
Homology/Alignments : Family Browser (UCSC)MMP10
Phylogenetic Trees/Animal Genes : TreeFamMMP10
Chemical/Protein Interactions : CTD4319
Chemical/Pharm GKB GenePA30868
Clinical trialMMP10
Cancer Resource (Charite)ENSG00000166670
Other databases
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
CoreMineMMP10
iHOPMMP10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Mar 31 09:27:23 CEST 2014

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