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MMP20 (matrix metallopeptidase 20)

Identity

Other namesAI2A2
MMP-20
HGNC (Hugo) MMP20
LocusID (NCBI) 9313
Location 11q22.2
Location_base_pair Starts at 102447566 and ends at 102496063 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MMP20   7167
Cards
Entrez_Gene (NCBI)MMP20  9313  matrix metallopeptidase 20
GeneCards (Weizmann)MMP20
Ensembl (Hinxton)ENSG00000137674 [Gene_View]  chr11:102447566-102496063 [Contig_View]  MMP20 [Vega]
ICGC DataPortalENSG00000137674
cBioPortalMMP20
AceView (NCBI)MMP20
Genatlas (Paris)MMP20
WikiGenes9313
SOURCE (Princeton)NM_004771
Genomic and cartography
GoldenPath (UCSC)MMP20  -  11q22.2   chr11:102447566-102496063 -  11q22.2   [Description]    (hg19-Feb_2009)
EnsemblMMP20 - 11q22.2 [CytoView]
Mapping of homologs : NCBIMMP20 [Mapview]
OMIM604629   612529   
Gene and transcription
Genbank (Entrez)AJ296177 BC152741 Y12779
RefSeq transcript (Entrez)NM_004771
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NG_012151 NT_033899 NW_001838042 NW_004929381
Consensus coding sequences : CCDS (NCBI)MMP20
Cluster EST : UnigeneHs.591946 [ NCBI ]
CGAP (NCI)Hs.591946
Alternative Splicing : Fast-db (Paris)GSHG0006124
Alternative Splicing GalleryENSG00000137674
Gene ExpressionMMP20 [ NCBI-GEO ]     MMP20 [ SEEK ]   MMP20 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60882 (Uniprot)
NextProtO60882  [Medical]
With graphics : InterProO60882
Splice isoforms : SwissVarO60882 (Swissvar)
Catalytic activity : Enzyme3.4.24.- [ Enzyme-Expasy ]   3.4.24.-3.4.24.- [ IntEnz-EBI ]   3.4.24.- [ BRENDA ]   3.4.24.- [ KEGG ]   
Domaine pattern : Prosite (Expaxy)CYSTEINE_SWITCH (PS00546)    HEMOPEXIN_2 (PS51642)    ZINC_PROTEASE (PS00142)   
Domains : Interpro (EBI)Hemopexin-like_dom [organisation]   Hemopexin-like_repeat [organisation]   MetalloPept_cat_dom [organisation]   MMP20 [organisation]   Pept_M10_metallopeptidase [organisation]   Pept_M10A [organisation]   Pept_M10A_stromelysin-type [organisation]   Pept_M10A_Zn_BS [organisation]   Peptidase_Metallo [organisation]   Peptidoglycan-bd-like [organisation]  
Related proteins : CluSTrO60882
Domain families : Pfam (Sanger)Hemopexin (PF00045)    Peptidase_M10 (PF00413)    PG_binding_1 (PF01471)   
Domain families : Pfam (NCBI)pfam00045    pfam00413    pfam01471   
Domain families : Smart (EMBL)HX (SM00120)  ZnMc (SM00235)  
DMDM Disease mutations9313
Blocks (Seattle)O60882
PDB (SRS)2JSD   
PDB (PDBSum)2JSD   
PDB (IMB)2JSD   
PDB (RSDB)2JSD   
Human Protein AtlasENSG00000137674 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasO60882
HPRD05218
IPIIPI00032404   
Protein Interaction databases
DIP (DOE-UCLA)O60882
IntAct (EBI)O60882
FunCoupENSG00000137674
BioGRIDMMP20
InParanoidO60882
Interologous Interaction database O60882
IntegromeDBMMP20
STRING (EMBL)MMP20
Ontologies - Pathways
Ontology : AmiGOmetalloendopeptidase activity  calcium ion binding  protein binding  extracellular region  proteinaceous extracellular matrix  extracellular space  proteolysis  zinc ion binding  extracellular matrix disassembly  extracellular matrix organization  collagen catabolic process  regulation of enamel mineralization  amelogenesis  
Ontology : EGO-EBImetalloendopeptidase activity  calcium ion binding  protein binding  extracellular region  proteinaceous extracellular matrix  extracellular space  proteolysis  zinc ion binding  extracellular matrix disassembly  extracellular matrix organization  collagen catabolic process  regulation of enamel mineralization  amelogenesis  
Protein Interaction DatabaseMMP20
Wikipedia pathwaysMMP20
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)MMP20
snp3D : Map Gene to Disease9313
SNP (GeneSNP Utah)MMP20
SNP : HGBaseMMP20
Genetic variants : HAPMAPMMP20
Exome VariantMMP20
1000_GenomesMMP20 
ICGC programENSG00000137674 
Somatic Mutations in Cancer : COSMICMMP20 
CONAN: Copy Number AnalysisMMP20 
Mutations and Diseases : HGMDMMP20
Mutations and Diseases : intOGenMMP20
Genomic VariantsMMP20  MMP20 [DGVbeta]
dbVarMMP20
ClinVarMMP20
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM604629    612529   
MedgenMMP20
GENETestsMMP20
Disease Genetic AssociationMMP20
Huge Navigator MMP20 [HugePedia]  MMP20 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneMMP20
Homology/Alignments : Family Browser (UCSC)MMP20
Phylogenetic Trees/Animal Genes : TreeFamMMP20
Chemical/Protein Interactions : CTD9313
Chemical/Pharm GKB GenePA30878
Clinical trialMMP20
Cancer Resource (Charite)ENSG00000137674
Other databases
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
CoreMineMMP20
iHOPMMP20
OncoSearchMMP20
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:56:21 CEST 2014

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