Atlas of Genetics and Cytogenetics in Oncology and Haematology

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MMP23B (matrix metallopeptidase 23B)

Identity

Alias (NCBI)MIFR
MIFR-1
MMP22
MMP23A
HGNC (Hugo) MMP23B
HGNC Alias symbMIFR
MIFR-1
HGNC Alias namematrix metalloproteinase 22
 femalysin
 matrix metalloproteinase in the female reproductive tract
HGNC Previous nameMMP22
HGNC Previous namematrix metalloproteinase 23B
LocusID (NCBI) 8510
Atlas_Id 41400
Location 1p36.33  [Link to chromosome band 1p36]
Location_base_pair Starts at 1632173 and ends at 1634654 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MMP23B   7171
Cards
Entrez_Gene (NCBI)MMP23B    matrix metallopeptidase 23B
AliasesMIFR; MIFR-1; MMP22; MMP23A
GeneCards (Weizmann)MMP23B
Ensembl hg19 (Hinxton)ENSG00000189409 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000189409 [Gene_View]  ENSG00000189409 [Sequence]  chr1:1632173-1634654 [Contig_View]  MMP23B [Vega]
ICGC DataPortalENSG00000189409
TCGA cBioPortalMMP23B
AceView (NCBI)MMP23B
Genatlas (Paris)MMP23B
SOURCE (Princeton)MMP23B
Genetics Home Reference (NIH)MMP23B
Genomic and cartography
GoldenPath hg38 (UCSC)MMP23B  -     chr1:1632173-1634654 +  1p36.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MMP23B  -     1p36.33   [Description]    (hg19-Feb_2009)
GoldenPathMMP23B - 1p36.33 [CytoView hg19]  MMP23B - 1p36.33 [CytoView hg38]
ImmunoBaseENSG00000189409
genome Data Viewer NCBIMMP23B [Mapview hg19]  
OMIM603321   
Gene and transcription
Genbank (Entrez)AB010961 AB010962 AF056200 AJ005256 AK297700
RefSeq transcript (Entrez)NM_006983
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MMP23B
Alternative Splicing GalleryENSG00000189409
Gene ExpressionMMP23B [ NCBI-GEO ]   MMP23B [ EBI - ARRAY_EXPRESS ]   MMP23B [ SEEK ]   MMP23B [ MEM ]
Gene Expression Viewer (FireBrowse)MMP23B [ Firebrowse - Broad ]
GenevisibleExpression of MMP23B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8510
GTEX Portal (Tissue expression)MMP23B
Human Protein AtlasENSG00000189409-MMP23B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75900   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75900  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75900
Splice isoforms : SwissVarO75900
Catalytic activity : Enzyme3.4.24.- [ Enzyme-Expasy ]   3.4.24.-3.4.24.- [ IntEnz-EBI ]   3.4.24.- [ BRENDA ]   3.4.24.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusO75900
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    SHKT (PS51670)    ZINC_PROTEASE (PS00142)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_sub    M10A_MMP    MetalloPept_cat_dom_sf    MMP23    Pept_M10_metallopeptidase    Pept_M10A    Peptidase_Metallo    ShKT_dom   
Domain families : Pfam (Sanger)Peptidase_M10 (PF00413)    ShK (PF01549)   
Domain families : Pfam (NCBI)pfam00413    pfam01549   
Domain families : Smart (EMBL)IG (SM00409)  ShKT (SM00254)  ZnMc (SM00235)  
Conserved Domain (NCBI)MMP23B
Blocks (Seattle)MMP23B
SuperfamilyO75900
Human Protein Atlas [tissue]ENSG00000189409-MMP23B [tissue]
Peptide AtlasO75900
HPRD04503
IPIIPI00012949   IPI00783823   IPI00719650   IPI00952582   IPI00413642   IPI00911097   IPI00968045   IPI00966773   IPI00968053   
Protein Interaction databases
DIP (DOE-UCLA)O75900
IntAct (EBI)O75900
BioGRIDMMP23B
STRING (EMBL)MMP23B
ZODIACMMP23B
Ontologies - Pathways
QuickGOO75900
Ontology : AmiGOreproduction  metalloendopeptidase activity  metalloendopeptidase activity  metalloendopeptidase activity  extracellular space  endoplasmic reticulum membrane  proteolysis  metallopeptidase activity  zinc ion binding  integral component of membrane  extracellular matrix organization  collagen catabolic process  extracellular matrix  collagen-containing extracellular matrix  
Ontology : EGO-EBIreproduction  metalloendopeptidase activity  metalloendopeptidase activity  metalloendopeptidase activity  extracellular space  endoplasmic reticulum membrane  proteolysis  metallopeptidase activity  zinc ion binding  integral component of membrane  extracellular matrix organization  collagen catabolic process  extracellular matrix  collagen-containing extracellular matrix  
NDEx NetworkMMP23B
Atlas of Cancer Signalling NetworkMMP23B
Wikipedia pathwaysMMP23B
Orthology - Evolution
OrthoDB8510
GeneTree (enSembl)ENSG00000189409
Phylogenetic Trees/Animal Genes : TreeFamMMP23B
HOGENOMO75900
Homologs : HomoloGeneMMP23B
Homology/Alignments : Family Browser (UCSC)MMP23B
Gene fusions - Rearrangements
Fusion : QuiverMMP23B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMMP23B [hg38]
dbVarMMP23B
ClinVarMMP23B
MonarchMMP23B
1000_GenomesMMP23B 
Exome Variant ServerMMP23B
GNOMAD BrowserENSG00000189409
Varsome BrowserMMP23B
Genomic Variants (DGV)MMP23B [DGVbeta]
DECIPHERMMP23B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMMP23B 
Mutations
ICGC Data PortalMMP23B 
TCGA Data PortalMMP23B 
Broad Tumor PortalMMP23B
OASIS PortalMMP23B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMMP23B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMMP23B
Mutations and Diseases : HGMDMMP23B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MMP23B
DgiDB (Drug Gene Interaction Database)MMP23B
DoCM (Curated mutations)MMP23B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MMP23B (select a term)
intoGenMMP23B
Cancer3DMMP23B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603321   
Orphanet
DisGeNETMMP23B
MedgenMMP23B
Genetic Testing Registry MMP23B
NextProtO75900 [Medical]
GENETestsMMP23B
Target ValidationMMP23B
Huge Navigator MMP23B [HugePedia]
ClinGenMMP23B
Clinical trials, drugs, therapy
MyCancerGenomeMMP23B
Protein Interactions : CTD
Pharm GKB GenePA30880
PharosO75900
Clinical trialMMP23B
Miscellaneous
canSAR (ICR)MMP23B (select the gene name)
HarmonizomeMMP23B
DataMed IndexMMP23B
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMMP23B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jan 1 18:27:11 CET 2021
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