MMP24 (matrix metallopeptidase 24)

2003-06-01  

Identity

HGNC
LOCATION
20q11.22
LOCUSID
ALIAS
MMP-24,MMP25,MT-MMP
FUSION GENES

Other Information

Locus ID:

NCBI: 10893
MIM: 604871
HGNC: 7172
Ensembl: ENSG00000125966

Variants:

dbSNP: 10893
ClinVar: 10893
TCGA: ENSG00000125966
COSMIC: MMP24

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125966ENST00000246186Q9Y5R2

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Extracellular matrix organizationREACTOMER-HSA-1474244
Degradation of the extracellular matrixREACTOMER-HSA-1474228
Activation of Matrix MetalloproteinasesREACTOMER-HSA-1592389

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
278698302017Inactivation of Capicua drives cancer metastasis.37
205466122010The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.19
149905672004Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase, MT5-MMP, to the plasma membrane by binding to its carboxyl end motif EWV.14
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
246690302014Expression of the matrix metalloproteases 2, 14, 24, and 25 and tissue inhibitor 3 as potential molecular markers in advanced human gastric cancer.10
179527612007Expression of membrane-type 5 matrix metalloproteinase in human endometrium and endometriosis.6
205875462010Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.6
126610332003mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human prostatic cell lines and their down-regulation in human malignant prostatic tissue.4
180629262007Identification of a novel human MT5-MMP transcript variant in multipotent NT2 cells.3

Citation

Dessen P

MMP24 (matrix metallopeptidase 24)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41401/mmp24