MND1 (meiotic nuclear divisions 1)

2016-10-01  

Identity

HGNC
LOCATION
4q31.3
LOCUSID
ALIAS
GAJ
FUSION GENES

Other Information

Locus ID:

NCBI: 84057
MIM: 611422
HGNC: 24839
Ensembl: ENSG00000121211

Variants:

dbSNP: 84057
ClinVar: 84057
TCGA: ENSG00000121211
COSMIC: MND1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121211ENST00000240488Q9BWT6
ENSG00000121211ENST00000504860D6R9E3
ENSG00000121211ENST00000508731D6RCT6
ENSG00000121211ENST00000509752D6RIA0
ENSG00000121211ENST00000622785A0A087WTC6

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Cell CycleREACTOMER-HSA-1640170
MeiosisREACTOMER-HSA-1500620
Meiotic recombinationREACTOMER-HSA-912446

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
164072602006Stimulation of DNA strand exchange by the human TBPIP/Hop2-Mnd1 complex.28
236759072013Expression analysis of MND1/GAJ, SPATA22, GAPDHS and ACR genes in testicular biopsies from non-obstructive azoospermia (NOA) patients.5
313935792019A predicted deleterious allele of the essential meiosis gene MND1, present in ~ 3% of East Asians, does not disrupt reproduction in mice.0

Citation

Dessen P

MND1 (meiotic nuclear divisions 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56399/mnd1