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MNDA (myeloid cell nuclear differentiation antigen)

Identity

Alias_symbol (synonym)PYHIN3
Other alias
HGNC (Hugo) MNDA
LocusID (NCBI) 4332
Atlas_Id 51305
Location 1q23.1  [Link to chromosome band 1q23]
Location_base_pair Starts at 158801168 and ends at 158819270 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ETV3 (1q23.1) / MNDA (1q23.1)NOTCH2 (1p12) / MNDA (1q23.1)RPLP2 (11p15.5) / MNDA (1q23.1)
ETV3 1q23.1 / MNDA 1q23.1NOTCH2 1p12 / MNDA 1q23.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MNDA   7183
Cards
Entrez_Gene (NCBI)MNDA  4332  myeloid cell nuclear differentiation antigen
AliasesPYHIN3
GeneCards (Weizmann)MNDA
Ensembl hg19 (Hinxton)ENSG00000163563 [Gene_View]  chr1:158801168-158819270 [Contig_View]  MNDA [Vega]
Ensembl hg38 (Hinxton)ENSG00000163563 [Gene_View]  chr1:158801168-158819270 [Contig_View]  MNDA [Vega]
ICGC DataPortalENSG00000163563
TCGA cBioPortalMNDA
AceView (NCBI)MNDA
Genatlas (Paris)MNDA
WikiGenes4332
SOURCE (Princeton)MNDA
Genetics Home Reference (NIH)MNDA
Genomic and cartography
GoldenPath hg19 (UCSC)MNDA  -     chr1:158801168-158819270 +  1q23.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MNDA  -     1q23.1   [Description]    (hg38-Dec_2013)
EnsemblMNDA - 1q23.1 [CytoView hg19]  MNDA - 1q23.1 [CytoView hg38]
Mapping of homologs : NCBIMNDA [Mapview hg19]  MNDA [Mapview hg38]
OMIM159553   
Gene and transcription
Genbank (Entrez)AK290392 AK313210 BC020715 BC032319 M81750
RefSeq transcript (Entrez)NM_002432
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)MNDA
Cluster EST : UnigeneHs.153837 [ NCBI ]
CGAP (NCI)Hs.153837
Alternative Splicing GalleryENSG00000163563
Gene ExpressionMNDA [ NCBI-GEO ]   MNDA [ EBI - ARRAY_EXPRESS ]   MNDA [ SEEK ]   MNDA [ MEM ]
Gene Expression Viewer (FireBrowse)MNDA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4332
GTEX Portal (Tissue expression)MNDA
Protein : pattern, domain, 3D structure
UniProt/SwissProtP41218   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP41218  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP41218
Splice isoforms : SwissVarP41218
PhosPhoSitePlusP41218
Domaine pattern : Prosite (Expaxy)DAPIN (PS50824)    HIN_200 (PS50834)   
Domains : Interpro (EBI)DAPIN    HIN200/IF120x    NA-bd_OB-fold   
Domain families : Pfam (Sanger)HIN (PF02760)    PYRIN (PF02758)   
Domain families : Pfam (NCBI)pfam02760    pfam02758   
Conserved Domain (NCBI)MNDA
DMDM Disease mutations4332
Blocks (Seattle)MNDA
PDB (SRS)2DBG   
PDB (PDBSum)2DBG   
PDB (IMB)2DBG   
PDB (RSDB)2DBG   
Structural Biology KnowledgeBase2DBG   
SCOP (Structural Classification of Proteins)2DBG   
CATH (Classification of proteins structures)2DBG   
SuperfamilyP41218
Human Protein AtlasENSG00000163563
Peptide AtlasP41218
HPRD15932
IPIIPI00013163   IPI00642185   
Protein Interaction databases
DIP (DOE-UCLA)P41218
IntAct (EBI)P41218
FunCoupENSG00000163563
BioGRIDMNDA
STRING (EMBL)MNDA
ZODIACMNDA
Ontologies - Pathways
QuickGOP41218
Ontology : AmiGODNA binding  protein binding  nucleus  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  cellular defense response  cellular response to DNA damage stimulus  negative regulation of B cell proliferation  positive regulation of apoptotic process  B cell receptor signaling pathway  extracellular exosome  
Ontology : EGO-EBIDNA binding  protein binding  nucleus  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  cellular defense response  cellular response to DNA damage stimulus  negative regulation of B cell proliferation  positive regulation of apoptotic process  B cell receptor signaling pathway  extracellular exosome  
NDEx NetworkMNDA
Atlas of Cancer Signalling NetworkMNDA
Wikipedia pathwaysMNDA
Orthology - Evolution
OrthoDB4332
GeneTree (enSembl)ENSG00000163563
Phylogenetic Trees/Animal Genes : TreeFamMNDA
HOVERGENP41218
HOGENOMP41218
Homologs : HomoloGeneMNDA
Homology/Alignments : Family Browser (UCSC)MNDA
Gene fusions - Rearrangements
Fusion : MitelmanETV3/MNDA [1q23.1/1q23.1]  [t(1;1)(q23;q23)]  
Fusion : MitelmanNOTCH2/MNDA [1p12/1q23.1]  [t(1;1)(p12;q23)]  
Fusion: TCGAETV3 1q23.1 MNDA 1q23.1 PRAD
Fusion: TCGANOTCH2 1p12 MNDA 1q23.1 OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMNDA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MNDA
dbVarMNDA
ClinVarMNDA
1000_GenomesMNDA 
Exome Variant ServerMNDA
ExAC (Exome Aggregation Consortium)MNDA (select the gene name)
Genetic variants : HAPMAP4332
Genomic Variants (DGV)MNDA [DGVbeta]
DECIPHER (Syndromes)1:158801168-158819270  ENSG00000163563
CONAN: Copy Number AnalysisMNDA 
Mutations
ICGC Data PortalMNDA 
TCGA Data PortalMNDA 
Broad Tumor PortalMNDA
OASIS PortalMNDA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMNDA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMNDA
intOGen PortalMNDA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MNDA
DgiDB (Drug Gene Interaction Database)MNDA
DoCM (Curated mutations)MNDA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MNDA (select a term)
intoGenMNDA
Cancer3DMNDA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM159553   
Orphanet
MedgenMNDA
Genetic Testing Registry MNDA
NextProtP41218 [Medical]
TSGene4332
GENETestsMNDA
Huge Navigator MNDA [HugePedia]
snp3D : Map Gene to Disease4332
BioCentury BCIQMNDA
ClinGenMNDA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4332
Chemical/Pharm GKB GenePA30895
Clinical trialMNDA
Miscellaneous
canSAR (ICR)MNDA (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMNDA
EVEXMNDA
GoPubMedMNDA
iHOPMNDA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:10:54 CEST 2017

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