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MNT (MAX network transcriptional repressor)

Identity

Alias_namesMAX binding protein
MNT, MAX dimerization protein
Alias_symbol (synonym)ROX
MXD6
MAD6
bHLHd3
Other alias
HGNC (Hugo) MNT
LocusID (NCBI) 4335
Atlas_Id 41412
Location 17p13.3  [Link to chromosome band 17p13]
Location_base_pair Starts at 2384060 and ends at 2400964 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MALAT1 (11q13.1) / MNT (17p13.3)MNT (17p13.3) / CDK19 (6q21)MNT (17p13.3) / RPL38 (17q25.1)
MNT (17p13.3) / SPRED1 (15q14)PKP1 (1q32.1) / MNT (17p13.3)SPRED1 (15q14) / MNT (17p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MNT   7188
Cards
Entrez_Gene (NCBI)MNT  4335  MAX network transcriptional repressor
AliasesMAD6; MXD6; ROX; bHLHd3
GeneCards (Weizmann)MNT
Ensembl hg19 (Hinxton)ENSG00000070444 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000070444 [Gene_View]  chr17:2384060-2400964 [Contig_View]  MNT [Vega]
ICGC DataPortalENSG00000070444
TCGA cBioPortalMNT
AceView (NCBI)MNT
Genatlas (Paris)MNT
WikiGenes4335
SOURCE (Princeton)MNT
Genetics Home Reference (NIH)MNT
Genomic and cartography
GoldenPath hg38 (UCSC)MNT  -     chr17:2384060-2400964 -  17p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MNT  -     17p13.3   [Description]    (hg19-Feb_2009)
EnsemblMNT - 17p13.3 [CytoView hg19]  MNT - 17p13.3 [CytoView hg38]
Mapping of homologs : NCBIMNT [Mapview hg19]  MNT [Mapview hg38]
OMIM603039   
Gene and transcription
Genbank (Entrez)AF318360 AK001561 AK291596 BC033186 BC117563
RefSeq transcript (Entrez)NM_020310
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MNT
Cluster EST : UnigeneHs.632239 [ NCBI ]
CGAP (NCI)Hs.632239
Alternative Splicing GalleryENSG00000070444
Gene ExpressionMNT [ NCBI-GEO ]   MNT [ EBI - ARRAY_EXPRESS ]   MNT [ SEEK ]   MNT [ MEM ]
Gene Expression Viewer (FireBrowse)MNT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4335
GTEX Portal (Tissue expression)MNT
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99583   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99583  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99583
Splice isoforms : SwissVarQ99583
PhosPhoSitePlusQ99583
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)MNT
DMDM Disease mutations4335
Blocks (Seattle)MNT
SuperfamilyQ99583
Human Protein AtlasENSG00000070444
Peptide AtlasQ99583
HPRD04331
IPIIPI00016177   IPI00383294   
Protein Interaction databases
DIP (DOE-UCLA)Q99583
IntAct (EBI)Q99583
FunCoupENSG00000070444
BioGRIDMNT
STRING (EMBL)MNT
ZODIACMNT
Ontologies - Pathways
QuickGOQ99583
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  chromatin binding  transcription factor activity, sequence-specific DNA binding  transcription coactivator activity  transcription corepressor activity  nucleus  nucleoplasm  transcription from RNA polymerase II promoter  multicellular organism development  cell aging  negative regulation of cell proliferation  protein dimerization activity  regulation of cell cycle  negative regulation of apoptotic signaling pathway  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  chromatin binding  transcription factor activity, sequence-specific DNA binding  transcription coactivator activity  transcription corepressor activity  nucleus  nucleoplasm  transcription from RNA polymerase II promoter  multicellular organism development  cell aging  negative regulation of cell proliferation  protein dimerization activity  regulation of cell cycle  negative regulation of apoptotic signaling pathway  
NDEx NetworkMNT
Atlas of Cancer Signalling NetworkMNT
Wikipedia pathwaysMNT
Orthology - Evolution
OrthoDB4335
GeneTree (enSembl)ENSG00000070444
Phylogenetic Trees/Animal Genes : TreeFamMNT
HOVERGENQ99583
HOGENOMQ99583
Homologs : HomoloGeneMNT
Homology/Alignments : Family Browser (UCSC)MNT
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMNT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MNT
dbVarMNT
ClinVarMNT
1000_GenomesMNT 
Exome Variant ServerMNT
ExAC (Exome Aggregation Consortium)MNT (select the gene name)
Genetic variants : HAPMAP4335
Genomic Variants (DGV)MNT [DGVbeta]
DECIPHERMNT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMNT 
Mutations
ICGC Data PortalMNT 
TCGA Data PortalMNT 
Broad Tumor PortalMNT
OASIS PortalMNT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMNT  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMNT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MNT
DgiDB (Drug Gene Interaction Database)MNT
DoCM (Curated mutations)MNT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MNT (select a term)
intoGenMNT
Cancer3DMNT(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603039   
Orphanet
MedgenMNT
Genetic Testing Registry MNT
NextProtQ99583 [Medical]
TSGene4335
GENETestsMNT
Target ValidationMNT
Huge Navigator MNT [HugePedia]
snp3D : Map Gene to Disease4335
BioCentury BCIQMNT
ClinGenMNT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4335
Chemical/Pharm GKB GenePA30898
Clinical trialMNT
Miscellaneous
canSAR (ICR)MNT (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMNT
EVEXMNT
GoPubMedMNT
iHOPMNT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:20:23 CEST 2017

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