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MOB1A (MOB kinase activator 1A)

Identity

Alias_namesC2orf6
MOBK1B
MOBKL1B
chromosome 2 open reading frame 6
MOB1, Mps One Binder kinase activator-like 1B (yeast)
MOB1 Mps One Binder homolog A (yeast)
Alias_symbol (synonym)FLJ10788
MOB1
FLJ11595
Mob4B
Mats1
Other aliasMATS1
HGNC (Hugo) MOB1A
LocusID (NCBI) 55233
Atlas_Id 52457
Location 2p13.1  [Link to chromosome band 2p13]
Location_base_pair Starts at 74152598 and ends at 74178967 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MOB1A (2p13.1) / GRIN2A (16p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MOB1A   16015
Cards
Entrez_Gene (NCBI)MOB1A  55233  MOB kinase activator 1A
AliasesC2orf6; MATS1; MOB1; MOBK1B; 
MOBKL1B; Mob4B
GeneCards (Weizmann)MOB1A
Ensembl hg19 (Hinxton)ENSG00000114978 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114978 [Gene_View]  chr2:74152598-74178967 [Contig_View]  MOB1A [Vega]
ICGC DataPortalENSG00000114978
TCGA cBioPortalMOB1A
AceView (NCBI)MOB1A
Genatlas (Paris)MOB1A
WikiGenes55233
SOURCE (Princeton)MOB1A
Genetics Home Reference (NIH)MOB1A
Genomic and cartography
GoldenPath hg38 (UCSC)MOB1A  -     chr2:74152598-74178967 -  2p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MOB1A  -     2p13.1   [Description]    (hg19-Feb_2009)
EnsemblMOB1A - 2p13.1 [CytoView hg19]  MOB1A - 2p13.1 [CytoView hg38]
Mapping of homologs : NCBIMOB1A [Mapview hg19]  MOB1A [Mapview hg38]
OMIM609281   
Gene and transcription
Genbank (Entrez)AB016839 AJ577474 AK001650 AK021657 AK023321
RefSeq transcript (Entrez)NM_001317110 NM_001317111 NM_001317112 NM_018221
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MOB1A
Cluster EST : UnigeneHs.602092 [ NCBI ]
CGAP (NCI)Hs.602092
Alternative Splicing GalleryENSG00000114978
Gene ExpressionMOB1A [ NCBI-GEO ]   MOB1A [ EBI - ARRAY_EXPRESS ]   MOB1A [ SEEK ]   MOB1A [ MEM ]
Gene Expression Viewer (FireBrowse)MOB1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55233
GTEX Portal (Tissue expression)MOB1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H8S9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H8S9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H8S9
Splice isoforms : SwissVarQ9H8S9
PhosPhoSitePlusQ9H8S9
Domains : Interpro (EBI)MOB_kinase_act_fam   
Domain families : Pfam (Sanger)Mob1_phocein (PF03637)   
Domain families : Pfam (NCBI)pfam03637   
Domain families : Smart (EMBL)Mob1_phocein (SM01388)  
Conserved Domain (NCBI)MOB1A
DMDM Disease mutations55233
Blocks (Seattle)MOB1A
PDB (SRS)1PI1    4J1V    4JIZ    5BRK    5BRM   
PDB (PDBSum)1PI1    4J1V    4JIZ    5BRK    5BRM   
PDB (IMB)1PI1    4J1V    4JIZ    5BRK    5BRM   
PDB (RSDB)1PI1    4J1V    4JIZ    5BRK    5BRM   
Structural Biology KnowledgeBase1PI1    4J1V    4JIZ    5BRK    5BRM   
SCOP (Structural Classification of Proteins)1PI1    4J1V    4JIZ    5BRK    5BRM   
CATH (Classification of proteins structures)1PI1    4J1V    4JIZ    5BRK    5BRM   
SuperfamilyQ9H8S9
Human Protein AtlasENSG00000114978
Peptide AtlasQ9H8S9
HPRD14727
IPIIPI00301518   IPI00386961   
Protein Interaction databases
DIP (DOE-UCLA)Q9H8S9
IntAct (EBI)Q9H8S9
FunCoupENSG00000114978
BioGRIDMOB1A
STRING (EMBL)MOB1A
ZODIACMOB1A
Ontologies - Pathways
QuickGOQ9H8S9
Ontology : AmiGOprotein binding  nucleus  nucleolus  cytosol  cytosol  hippo signaling  hippo signaling  metal ion binding  extracellular exosome  
Ontology : EGO-EBIprotein binding  nucleus  nucleolus  cytosol  cytosol  hippo signaling  hippo signaling  metal ion binding  extracellular exosome  
Pathways : KEGGHippo signaling pathway   
NDEx NetworkMOB1A
Atlas of Cancer Signalling NetworkMOB1A
Wikipedia pathwaysMOB1A
Orthology - Evolution
OrthoDB55233
GeneTree (enSembl)ENSG00000114978
Phylogenetic Trees/Animal Genes : TreeFamMOB1A
HOVERGENQ9H8S9
HOGENOMQ9H8S9
Homologs : HomoloGeneMOB1A
Homology/Alignments : Family Browser (UCSC)MOB1A
Gene fusions - Rearrangements
Fusion : MitelmanMOB1A/GRIN2A [2p13.1/16p13.2]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMOB1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MOB1A
dbVarMOB1A
ClinVarMOB1A
1000_GenomesMOB1A 
Exome Variant ServerMOB1A
ExAC (Exome Aggregation Consortium)MOB1A (select the gene name)
Genetic variants : HAPMAP55233
Genomic Variants (DGV)MOB1A [DGVbeta]
DECIPHERMOB1A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMOB1A 
Mutations
ICGC Data PortalMOB1A 
TCGA Data PortalMOB1A 
Broad Tumor PortalMOB1A
OASIS PortalMOB1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMOB1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMOB1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MOB1A
DgiDB (Drug Gene Interaction Database)MOB1A
DoCM (Curated mutations)MOB1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MOB1A (select a term)
intoGenMOB1A
Cancer3DMOB1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609281   
Orphanet
MedgenMOB1A
Genetic Testing Registry MOB1A
NextProtQ9H8S9 [Medical]
TSGene55233
GENETestsMOB1A
Target ValidationMOB1A
Huge Navigator MOB1A [HugePedia]
snp3D : Map Gene to Disease55233
BioCentury BCIQMOB1A
ClinGenMOB1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55233
Chemical/Pharm GKB GenePA25894
Clinical trialMOB1A
Miscellaneous
canSAR (ICR)MOB1A (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMOB1A
EVEXMOB1A
GoPubMedMOB1A
iHOPMOB1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:20:23 CEST 2017

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