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MOB1B (MOB kinase activator 1B)

Identity

Alias_namesMOBKL1A
MOB1, Mps One Binder kinase activator-like 1A (yeast)
MOB1 Mps One Binder homolog B (yeast)
Alias_symbol (synonym)MOB4A
Other aliasMATS2
HGNC (Hugo) MOB1B
LocusID (NCBI) 92597
Atlas_Id 70356
Location 4q13.3  [Link to chromosome band 4q13]
Location_base_pair Starts at 70902340 and ends at 70988174 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MOB1B (4q13.3) / MOB1B (4q13.3)MOB1B (4q13.3) / MUC7 (4q13.3)MOB1B (4q13.3) / PLPP4 (10q26.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MOB1B   29801
Cards
Entrez_Gene (NCBI)MOB1B  92597  MOB kinase activator 1B
AliasesMATS2; MOB4A; MOBKL1A
GeneCards (Weizmann)MOB1B
Ensembl hg19 (Hinxton)ENSG00000173542 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173542 [Gene_View]  chr4:70902340-70988174 [Contig_View]  MOB1B [Vega]
ICGC DataPortalENSG00000173542
TCGA cBioPortalMOB1B
AceView (NCBI)MOB1B
Genatlas (Paris)MOB1B
WikiGenes92597
SOURCE (Princeton)MOB1B
Genetics Home Reference (NIH)MOB1B
Genomic and cartography
GoldenPath hg38 (UCSC)MOB1B  -     chr4:70902340-70988174 +  4q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MOB1B  -     4q13.3   [Description]    (hg19-Feb_2009)
EnsemblMOB1B - 4q13.3 [CytoView hg19]  MOB1B - 4q13.3 [CytoView hg38]
Mapping of homologs : NCBIMOB1B [Mapview hg19]  MOB1B [Mapview hg38]
OMIM609282   
Gene and transcription
Genbank (Entrez)AA417950 AJ577473 AK093545 AK299481 AK313513
RefSeq transcript (Entrez)NM_001244766 NM_001244767 NM_173468
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MOB1B
Cluster EST : UnigeneHs.744715 [ NCBI ]
CGAP (NCI)Hs.744715
Alternative Splicing GalleryENSG00000173542
Gene ExpressionMOB1B [ NCBI-GEO ]   MOB1B [ EBI - ARRAY_EXPRESS ]   MOB1B [ SEEK ]   MOB1B [ MEM ]
Gene Expression Viewer (FireBrowse)MOB1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)92597
GTEX Portal (Tissue expression)MOB1B
Human Protein AtlasENSG00000173542-MOB1B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7L9L4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7L9L4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7L9L4
Splice isoforms : SwissVarQ7L9L4
PhosPhoSitePlusQ7L9L4
Domains : Interpro (EBI)MOB_kinase_act_fam   
Domain families : Pfam (Sanger)Mob1_phocein (PF03637)   
Domain families : Pfam (NCBI)pfam03637   
Domain families : Smart (EMBL)Mob1_phocein (SM01388)  
Conserved Domain (NCBI)MOB1B
DMDM Disease mutations92597
Blocks (Seattle)MOB1B
SuperfamilyQ7L9L4
Human Protein Atlas [tissue]ENSG00000173542-MOB1B [tissue]
Peptide AtlasQ7L9L4
HPRD17582
IPIIPI00514212   IPI00902783   IPI00872556   IPI00963939   
Protein Interaction databases
DIP (DOE-UCLA)Q7L9L4
IntAct (EBI)Q7L9L4
FunCoupENSG00000173542
BioGRIDMOB1B
STRING (EMBL)MOB1B
ZODIACMOB1B
Ontologies - Pathways
QuickGOQ7L9L4
Ontology : AmiGOprotein binding  nucleus  nucleolus  cytoplasm  cytosol  cytosol  kinase activator activity  kinase binding  regulation of protein autophosphorylation  hippo signaling  hippo signaling  positive regulation of phosphorylation  metal ion binding  extracellular exosome  
Ontology : EGO-EBIprotein binding  nucleus  nucleolus  cytoplasm  cytosol  cytosol  kinase activator activity  kinase binding  regulation of protein autophosphorylation  hippo signaling  hippo signaling  positive regulation of phosphorylation  metal ion binding  extracellular exosome  
Pathways : KEGGHippo signaling pathway   
NDEx NetworkMOB1B
Atlas of Cancer Signalling NetworkMOB1B
Wikipedia pathwaysMOB1B
Orthology - Evolution
OrthoDB92597
GeneTree (enSembl)ENSG00000173542
Phylogenetic Trees/Animal Genes : TreeFamMOB1B
HOVERGENQ7L9L4
HOGENOMQ7L9L4
Homologs : HomoloGeneMOB1B
Homology/Alignments : Family Browser (UCSC)MOB1B
Gene fusions - Rearrangements
Fusion: Tumor Portal MOB1B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMOB1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MOB1B
dbVarMOB1B
ClinVarMOB1B
1000_GenomesMOB1B 
Exome Variant ServerMOB1B
ExAC (Exome Aggregation Consortium)ENSG00000173542
GNOMAD BrowserENSG00000173542
Genetic variants : HAPMAP92597
Genomic Variants (DGV)MOB1B [DGVbeta]
DECIPHERMOB1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMOB1B 
Mutations
ICGC Data PortalMOB1B 
TCGA Data PortalMOB1B 
Broad Tumor PortalMOB1B
OASIS PortalMOB1B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMOB1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MOB1B
DgiDB (Drug Gene Interaction Database)MOB1B
DoCM (Curated mutations)MOB1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MOB1B (select a term)
intoGenMOB1B
Cancer3DMOB1B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609282   
Orphanet
MedgenMOB1B
Genetic Testing Registry MOB1B
NextProtQ7L9L4 [Medical]
TSGene92597
GENETestsMOB1B
Target ValidationMOB1B
Huge Navigator MOB1B [HugePedia]
snp3D : Map Gene to Disease92597
BioCentury BCIQMOB1B
ClinGenMOB1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD92597
Chemical/Pharm GKB GenePA134871841
Clinical trialMOB1B
Miscellaneous
canSAR (ICR)MOB1B (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMOB1B
EVEXMOB1B
GoPubMedMOB1B
iHOPMOB1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:17:31 CET 2017

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