MOB2 (MOB kinase activator 2)

2003-02-01  

Identity

HGNC
MOB2
LOCATION
11p15.5
LOCUSID
81532
ALIAS
HCCA2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 81532
MIM: 611969
HGNC: 24904
Ensembl: ENSG00000182208

Variants:

dbSNP: 81532
ClinVar: 81532
TCGA: ENSG00000182208
COSMIC: MOB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182208ENST00000329957Q70IA6
ENSG00000182208ENST00000614710A0A087WVS8

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
208898532011Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.65
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
150670042004Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases.38
206249132010Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases.26
254600432015Regulation of DNA damage responses and cell cycle progression by hMOB2.13
257792242015Modulation of tumor cell migration, invasion and cell-matrix adhesion by human monopolar spindle-one-binder 2.3
233261342012Growth-inhibitory effects of MOB2 on human hepatic carcinoma cell line SMMC-7721.1

Citation

Dessen P

MOB2 (MOB kinase activator 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40796/mob2