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MOB2 (MOB kinase activator 2)

Identity

Alias_symbol (synonym)HCCA2
Other alias
HGNC (Hugo) MOB2
LocusID (NCBI) 81532
Atlas_Id 40796
Location 11p15.5  [Link to chromosome band 11p15]
Location_base_pair Starts at 1490678 and ends at 1508009 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CCDC93 (2q14.1) / MOB2 (11p15.5)EPS15L1 (19p13.11) / MOB2 (11p15.5)MOB2 (11p15.5) / BCYRN1 (Xq13.1)
MOB2 (11p15.5) / DHX38 (16q22.2)MOB2 (11p15.5) / HSPB7 (1p36.13)MOB2 (11p15.5) / MOB2 (11p15.5)
MOB2 (11p15.5) / PRRC2C (1q24.3)MOB2 (11p15.5) / RPS3 (11q13.4)MOB2 (11p15.5) / TNFAIP8 (5q23.1)
MOB2 (11p15.5) / WIPI1 (17q24.2)MRPL52 (14q11.2) / MOB2 (11p15.5)SERPINA1 (14q32.13) / MOB2 (11p15.5)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MOB2   24904
Cards
Entrez_Gene (NCBI)MOB2  81532  MOB kinase activator 2
AliasesHCCA2
GeneCards (Weizmann)MOB2
Ensembl hg19 (Hinxton)ENSG00000182208 [Gene_View]  chr11:1490678-1508009 [Contig_View]  MOB2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000182208 [Gene_View]  chr11:1490678-1508009 [Contig_View]  MOB2 [Vega]
ICGC DataPortalENSG00000182208
TCGA cBioPortalMOB2
AceView (NCBI)MOB2
Genatlas (Paris)MOB2
WikiGenes81532
SOURCE (Princeton)MOB2
Genetics Home Reference (NIH)MOB2
Genomic and cartography
GoldenPath hg19 (UCSC)MOB2  -     chr11:1490678-1508009 -  11p15.5   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MOB2  -     11p15.5   [Description]    (hg38-Dec_2013)
EnsemblMOB2 - 11p15.5 [CytoView hg19]  MOB2 - 11p15.5 [CytoView hg38]
Mapping of homologs : NCBIMOB2 [Mapview hg19]  MOB2 [Mapview hg38]
OMIM611969   
Gene and transcription
Genbank (Entrez)AB028173 AB066564 AJ580639 AK057350 AK296658
RefSeq transcript (Entrez)NM_001172223 NM_053005
RefSeq genomic (Entrez)NC_000011 NC_018922 NT_009237 NW_004929378
Consensus coding sequences : CCDS (NCBI)MOB2
Cluster EST : UnigeneHs.370360 [ NCBI ]
CGAP (NCI)Hs.370360
Alternative Splicing GalleryENSG00000182208
Gene ExpressionMOB2 [ NCBI-GEO ]   MOB2 [ EBI - ARRAY_EXPRESS ]   MOB2 [ SEEK ]   MOB2 [ MEM ]
Gene Expression Viewer (FireBrowse)MOB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81532
GTEX Portal (Tissue expression)MOB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ70IA6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ70IA6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ70IA6
Splice isoforms : SwissVarQ70IA6
PhosPhoSitePlusQ70IA6
Domains : Interpro (EBI)MOB_kinase_act_fam   
Domain families : Pfam (Sanger)Mob1_phocein (PF03637)   
Domain families : Pfam (NCBI)pfam03637   
Conserved Domain (NCBI)MOB2
DMDM Disease mutations81532
Blocks (Seattle)MOB2
SuperfamilyQ70IA6
Human Protein AtlasENSG00000182208
Peptide AtlasQ70IA6
HPRD17581
IPIIPI00939594   IPI00514453   IPI00418248   
Protein Interaction databases
DIP (DOE-UCLA)Q70IA6
IntAct (EBI)Q70IA6
FunCoupENSG00000182208
BioGRIDMOB2
STRING (EMBL)MOB2
ZODIACMOB2
Ontologies - Pathways
QuickGOQ70IA6
Ontology : AmiGOpositive regulation of protein phosphorylation  nucleus  nucleolus  cytoplasm  positive regulation of neuron projection development  actin cytoskeleton organization  neuron projection terminus  metal ion binding  perinuclear region of cytoplasm  
Ontology : EGO-EBIpositive regulation of protein phosphorylation  nucleus  nucleolus  cytoplasm  positive regulation of neuron projection development  actin cytoskeleton organization  neuron projection terminus  metal ion binding  perinuclear region of cytoplasm  
NDEx NetworkMOB2
Atlas of Cancer Signalling NetworkMOB2
Wikipedia pathwaysMOB2
Orthology - Evolution
OrthoDB81532
GeneTree (enSembl)ENSG00000182208
Phylogenetic Trees/Animal Genes : TreeFamMOB2
HOVERGENQ70IA6
HOGENOMQ70IA6
Homologs : HomoloGeneMOB2
Homology/Alignments : Family Browser (UCSC)MOB2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMOB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MOB2
dbVarMOB2
ClinVarMOB2
1000_GenomesMOB2 
Exome Variant ServerMOB2
ExAC (Exome Aggregation Consortium)MOB2 (select the gene name)
Genetic variants : HAPMAP81532
Genomic Variants (DGV)MOB2 [DGVbeta]
DECIPHER (Syndromes)11:1490678-1508009  ENSG00000182208
CONAN: Copy Number AnalysisMOB2 
Mutations
ICGC Data PortalMOB2 
TCGA Data PortalMOB2 
Broad Tumor PortalMOB2
OASIS PortalMOB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMOB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMOB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MOB2
DgiDB (Drug Gene Interaction Database)MOB2
DoCM (Curated mutations)MOB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MOB2 (select a term)
intoGenMOB2
Cancer3DMOB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611969   
Orphanet
MedgenMOB2
Genetic Testing Registry MOB2
NextProtQ70IA6 [Medical]
TSGene81532
GENETestsMOB2
Huge Navigator MOB2 [HugePedia]
snp3D : Map Gene to Disease81532
BioCentury BCIQMOB2
ClinGenMOB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81532
Clinical trialMOB2
Miscellaneous
canSAR (ICR)MOB2 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMOB2
EVEXMOB2
GoPubMedMOB2
iHOPMOB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:10:54 CEST 2017

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