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MOB4 (MOB family member 4, phocein)

Identity

Alias_namesPREI3
MOBKL3
preimplantation protein 3
MOB1, Mps One Binder kinase activator-like 3 (yeast)
Alias_symbol (synonym)MOB3
DKFZP564M112
CGI-95
2C4D
PHOCN
Other aliasMOB1
HGNC (Hugo) MOB4
LocusID (NCBI) 25843
Atlas_Id 54904
Location 2q33.1  [Link to chromosome band 2q33]
Location_base_pair Starts at 197516043 and ends at 197553699 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
HSPE1 (2q33.1) / MOB4 (2q33.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MOB4   17261
Cards
Entrez_Gene (NCBI)MOB4  25843  MOB family member 4, phocein
Aliases2C4D; CGI-95; MOB1; MOB3; 
MOBKL3; PHOCN; PREI3
GeneCards (Weizmann)MOB4
Ensembl hg19 (Hinxton)ENSG00000115540 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115540 [Gene_View]  chr2:197516043-197553699 [Contig_View]  MOB4 [Vega]
ICGC DataPortalENSG00000115540
TCGA cBioPortalMOB4
AceView (NCBI)MOB4
Genatlas (Paris)MOB4
WikiGenes25843
SOURCE (Princeton)MOB4
Genetics Home Reference (NIH)MOB4
Genomic and cartography
GoldenPath hg38 (UCSC)MOB4  -     chr2:197516043-197553699 +  2q33.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MOB4  -     2q33.1   [Description]    (hg19-Feb_2009)
EnsemblMOB4 - 2q33.1 [CytoView hg19]  MOB4 - 2q33.1 [CytoView hg38]
Mapping of homologs : NCBIMOB4 [Mapview hg19]  MOB4 [Mapview hg38]
OMIM609361   
Gene and transcription
Genbank (Entrez)AB015441 AF093825 AF151853 AF250319 AJ580638
RefSeq transcript (Entrez)NM_001100819 NM_001204094 NM_015387 NM_199482
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MOB4
Cluster EST : UnigeneHs.633165 [ NCBI ]
CGAP (NCI)Hs.633165
Alternative Splicing GalleryENSG00000115540
Gene ExpressionMOB4 [ NCBI-GEO ]   MOB4 [ EBI - ARRAY_EXPRESS ]   MOB4 [ SEEK ]   MOB4 [ MEM ]
Gene Expression Viewer (FireBrowse)MOB4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25843
GTEX Portal (Tissue expression)MOB4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3A3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3A3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3A3
Splice isoforms : SwissVarQ9Y3A3
PhosPhoSitePlusQ9Y3A3
Domains : Interpro (EBI)MOB_kinase_act_fam   
Domain families : Pfam (Sanger)Mob1_phocein (PF03637)   
Domain families : Pfam (NCBI)pfam03637   
Domain families : Smart (EMBL)Mob1_phocein (SM01388)  
Conserved Domain (NCBI)MOB4
DMDM Disease mutations25843
Blocks (Seattle)MOB4
SuperfamilyQ9Y3A3
Human Protein AtlasENSG00000115540
Peptide AtlasQ9Y3A3
HPRD10165
IPIIPI00386122   IPI00398774   IPI00856011   IPI00917634   IPI00915921   IPI00915769   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3A3
IntAct (EBI)Q9Y3A3
FunCoupENSG00000115540
BioGRIDMOB4
STRING (EMBL)MOB4
ZODIACMOB4
Ontologies - Pathways
QuickGOQ9Y3A3
Ontology : AmiGOprotein binding  cytoplasm  Golgi apparatus  cytosol  transport  kinase binding  Golgi cisterna membrane  neuronal cell body  dendritic spine  metal ion binding  perinuclear region of cytoplasm  
Ontology : EGO-EBIprotein binding  cytoplasm  Golgi apparatus  cytosol  transport  kinase binding  Golgi cisterna membrane  neuronal cell body  dendritic spine  metal ion binding  perinuclear region of cytoplasm  
NDEx NetworkMOB4
Atlas of Cancer Signalling NetworkMOB4
Wikipedia pathwaysMOB4
Orthology - Evolution
OrthoDB25843
GeneTree (enSembl)ENSG00000115540
Phylogenetic Trees/Animal Genes : TreeFamMOB4
HOVERGENQ9Y3A3
HOGENOMQ9Y3A3
Homologs : HomoloGeneMOB4
Homology/Alignments : Family Browser (UCSC)MOB4
Gene fusions - Rearrangements
Fusion : MitelmanHSPE1/MOB4 [2q33.1/2q33.1]  [t(2;2)(q33;q33)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMOB4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MOB4
dbVarMOB4
ClinVarMOB4
1000_GenomesMOB4 
Exome Variant ServerMOB4
ExAC (Exome Aggregation Consortium)MOB4 (select the gene name)
Genetic variants : HAPMAP25843
Genomic Variants (DGV)MOB4 [DGVbeta]
DECIPHERMOB4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMOB4 
Mutations
ICGC Data PortalMOB4 
TCGA Data PortalMOB4 
Broad Tumor PortalMOB4
OASIS PortalMOB4 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMOB4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MOB4
DgiDB (Drug Gene Interaction Database)MOB4
DoCM (Curated mutations)MOB4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MOB4 (select a term)
intoGenMOB4
Cancer3DMOB4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609361   
Orphanet
MedgenMOB4
Genetic Testing Registry MOB4
NextProtQ9Y3A3 [Medical]
TSGene25843
GENETestsMOB4
Target ValidationMOB4
Huge Navigator MOB4 [HugePedia]
snp3D : Map Gene to Disease25843
BioCentury BCIQMOB4
ClinGenMOB4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25843
Chemical/Pharm GKB GenePA162396053
Clinical trialMOB4
Miscellaneous
canSAR (ICR)MOB4 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMOB4
EVEXMOB4
GoPubMedMOB4
iHOPMOB4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:08:06 CEST 2017

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