Atlas of Genetics and Cytogenetics in Oncology and Haematology

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MOCOS (molybdenum cofactor sulfurase)

Identity

Alias (NCBI)HMCS
MCS
MOS
HGNC (Hugo) MOCOS
HGNC Alias symbHMCS
FLJ20733
MOS
LocusID (NCBI) 55034
Atlas_Id 70360
Location 18q12.2  [Link to chromosome band 18q12]
Location_base_pair Starts at 36187210 and ends at 36268722 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FHOD3 (18q12.2) / MOCOS (18q12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  FHOD3/MOCOS (18q12)

External links

Nomenclature
HGNC (Hugo)MOCOS   18234
Cards
Entrez_Gene (NCBI)MOCOS    molybdenum cofactor sulfurase
AliasesHMCS; MCS; MOS
GeneCards (Weizmann)MOCOS
Ensembl hg19 (Hinxton)ENSG00000075643 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000075643 [Gene_View]  ENSG00000075643 [Sequence]  chr18:36187210-36268722 [Contig_View]  MOCOS [Vega]
ICGC DataPortalENSG00000075643
TCGA cBioPortalMOCOS
AceView (NCBI)MOCOS
Genatlas (Paris)MOCOS
SOURCE (Princeton)MOCOS
Genetics Home Reference (NIH)MOCOS
Genomic and cartography
GoldenPath hg38 (UCSC)MOCOS  -     chr18:36187210-36268722 +  18q12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MOCOS  -     18q12.2   [Description]    (hg19-Feb_2009)
GoldenPathMOCOS - 18q12.2 [CytoView hg19]  MOCOS - 18q12.2 [CytoView hg38]
ImmunoBaseENSG00000075643
genome Data Viewer NCBIMOCOS [Mapview hg19]  
OMIM603592   613274   
Gene and transcription
Genbank (Entrez)AK000740 AK222886 AL834481 BC012079 BQ931455
RefSeq transcript (Entrez)NM_017947
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MOCOS
Alternative Splicing GalleryENSG00000075643
Gene ExpressionMOCOS [ NCBI-GEO ]   MOCOS [ EBI - ARRAY_EXPRESS ]   MOCOS [ SEEK ]   MOCOS [ MEM ]
Gene Expression Viewer (FireBrowse)MOCOS [ Firebrowse - Broad ]
GenevisibleExpression of MOCOS in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55034
GTEX Portal (Tissue expression)MOCOS
Human Protein AtlasENSG00000075643-MOCOS [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96EN8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96EN8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96EN8
Splice isoforms : SwissVarQ96EN8
PhosPhoSitePlusQ96EN8
Domaine pattern : Prosite (Expaxy)MOSC (PS51340)   
Domains : Interpro (EBI)Aminotrans_V_dom    MoCF_Sase_C    MoCo_sulfurase    MOSC_N    PyrdxlP-dep_Trfase    PyrdxlP-dep_Trfase_dom1    PyrdxlP-dep_Trfase_major    Pyrv_Knase-like_insert_dom_sf   
Domain families : Pfam (Sanger)Aminotran_5 (PF00266)    MOSC (PF03473)    MOSC_N (PF03476)   
Domain families : Pfam (NCBI)pfam00266    pfam03473    pfam03476   
Conserved Domain (NCBI)MOCOS
Blocks (Seattle)MOCOS
SuperfamilyQ96EN8
Human Protein Atlas [tissue]ENSG00000075643-MOCOS [tissue]
Peptide AtlasQ96EN8
HPRD17585
IPIIPI00304895   
Protein Interaction databases
DIP (DOE-UCLA)Q96EN8
IntAct (EBI)Q96EN8
BioGRIDMOCOS
STRING (EMBL)MOCOS
ZODIACMOCOS
Ontologies - Pathways
QuickGOQ96EN8
Ontology : AmiGOprotein binding  cellular_component  cytosol  Mo-molybdopterin cofactor biosynthetic process  Mo-molybdopterin cofactor sulfurase activity  lyase activity  molybdenum ion binding  pyridoxal phosphate binding  molybdopterin cofactor biosynthetic process  molybdopterin cofactor metabolic process  molybdenum cofactor sulfurtransferase activity  
Ontology : EGO-EBIprotein binding  cellular_component  cytosol  Mo-molybdopterin cofactor biosynthetic process  Mo-molybdopterin cofactor sulfurase activity  lyase activity  molybdenum ion binding  pyridoxal phosphate binding  molybdopterin cofactor biosynthetic process  molybdopterin cofactor metabolic process  molybdenum cofactor sulfurtransferase activity  
NDEx NetworkMOCOS
Atlas of Cancer Signalling NetworkMOCOS
Wikipedia pathwaysMOCOS
Orthology - Evolution
OrthoDB55034
GeneTree (enSembl)ENSG00000075643
Phylogenetic Trees/Animal Genes : TreeFamMOCOS
HOGENOMQ96EN8
Homologs : HomoloGeneMOCOS
Homology/Alignments : Family Browser (UCSC)MOCOS
Gene fusions - Rearrangements
Fusion : QuiverMOCOS
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMOCOS [hg38]
dbVarMOCOS
ClinVarMOCOS
MonarchMOCOS
1000_GenomesMOCOS 
Exome Variant ServerMOCOS
GNOMAD BrowserENSG00000075643
Varsome BrowserMOCOS
Genomic Variants (DGV)MOCOS [DGVbeta]
DECIPHERMOCOS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMOCOS 
Mutations
ICGC Data PortalMOCOS 
TCGA Data PortalMOCOS 
Broad Tumor PortalMOCOS
OASIS PortalMOCOS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMOCOS  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMOCOS
Mutations and Diseases : HGMDMOCOS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MOCOS
DgiDB (Drug Gene Interaction Database)MOCOS
DoCM (Curated mutations)MOCOS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MOCOS (select a term)
intoGenMOCOS
Cancer3DMOCOS(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603592    613274   
Orphanet12435   
DisGeNETMOCOS
MedgenMOCOS
Genetic Testing Registry MOCOS
NextProtQ96EN8 [Medical]
GENETestsMOCOS
Target ValidationMOCOS
Huge Navigator MOCOS [HugePedia]
ClinGenMOCOS
Clinical trials, drugs, therapy
MyCancerGenomeMOCOS
Protein Interactions : CTD
Pharm GKB GenePA134964534
Clinical trialMOCOS
Miscellaneous
canSAR (ICR)MOCOS (select the gene name)
HarmonizomeMOCOS
DataMed IndexMOCOS
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMOCOS
EVEXMOCOS
GoPubMedMOCOS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 17:17:42 CET 2020
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