Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MOCS2 (molybdenum cofactor synthesis 2)

Identity

Alias_symbol (synonym)MOCO1
Other aliasMCBPE
MOCODB
MPTS
HGNC (Hugo) MOCS2
LocusID (NCBI) 4338
Atlas_Id 70362
Location 5q11.2  [Link to chromosome band 5q11]
Location_base_pair Starts at 52391509 and ends at 52405602 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ARL15 (5q11.2) / MOCS2 (5q11.2)MOCS2 (5q11.2) / DAB1 (1p32.2)MOCS2 (5q11.2) / PTH2R (2q34)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MOCS2   7193
Cards
Entrez_Gene (NCBI)MOCS2  4338  molybdenum cofactor synthesis 2
AliasesMCBPE; MOCO1; MOCODB; MPTS
GeneCards (Weizmann)MOCS2
Ensembl hg19 (Hinxton)ENSG00000164172 [Gene_View]  chr5:52391509-52405602 [Contig_View]  MOCS2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000164172 [Gene_View]  chr5:52391509-52405602 [Contig_View]  MOCS2 [Vega]
ICGC DataPortalENSG00000164172
TCGA cBioPortalMOCS2
AceView (NCBI)MOCS2
Genatlas (Paris)MOCS2
WikiGenes4338
SOURCE (Princeton)MOCS2
Genetics Home Reference (NIH)MOCS2
Genomic and cartography
GoldenPath hg19 (UCSC)MOCS2  -     chr5:52391509-52405602 -  5q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MOCS2  -     5q11.2   [Description]    (hg38-Dec_2013)
EnsemblMOCS2 - 5q11.2 [CytoView hg19]  MOCS2 - 5q11.2 [CytoView hg38]
Mapping of homologs : NCBIMOCS2 [Mapview hg19]  MOCS2 [Mapview hg38]
OMIM252160   603708   
Gene and transcription
Genbank (Entrez)AA252410 AF091871 AF091871 AF117815 AF117815
RefSeq transcript (Entrez)NM_004531 NM_176806
RefSeq genomic (Entrez)NC_000005 NC_018916 NG_008435 NT_034772 NW_004929322
Consensus coding sequences : CCDS (NCBI)MOCS2
Cluster EST : UnigeneHs.594335 [ NCBI ]
CGAP (NCI)Hs.594335
Alternative Splicing GalleryENSG00000164172
Gene ExpressionMOCS2 [ NCBI-GEO ]   MOCS2 [ EBI - ARRAY_EXPRESS ]   MOCS2 [ SEEK ]   MOCS2 [ MEM ]
Gene Expression Viewer (FireBrowse)MOCS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4338
GTEX Portal (Tissue expression)MOCS2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO96033   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO96033  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO96033
Splice isoforms : SwissVarO96033
PhosPhoSitePlusO96033
Domains : Interpro (EBI)Beta-grasp_dom    MOCS2A    Mopterin_su_1    Mopterin_synth/thiamin_S_b    ThiS/MoaD   
Domain families : Pfam (Sanger)ThiS (PF02597)   
Domain families : Pfam (NCBI)pfam02597   
Conserved Domain (NCBI)MOCS2
DMDM Disease mutations4338
Blocks (Seattle)MOCS2
SuperfamilyO96033
Human Protein AtlasENSG00000164172
Peptide AtlasO96033
HPRD04750
IPIIPI00005218   IPI00002968   IPI00984324   
Protein Interaction databases
DIP (DOE-UCLA)O96033
IntAct (EBI)O96033
FunCoupENSG00000164172
BioGRIDMOCS2
STRING (EMBL)MOCS2
ZODIACMOCS2
Ontologies - Pathways
QuickGOO96033
Ontology : AmiGOnucleotide binding  nucleus  cytoplasm  cytosol  cytosol  vitamin metabolic process  water-soluble vitamin metabolic process  Mo-molybdopterin cofactor biosynthetic process  Mo-molybdopterin cofactor biosynthetic process  molybdopterin synthase complex  molybdopterin synthase complex  molybdopterin synthase activity  molybdopterin synthase activity  molybdopterin synthase activity  molybdopterin cofactor biosynthetic process  identical protein binding  small molecule metabolic process  extracellular exosome  
Ontology : EGO-EBInucleotide binding  nucleus  cytoplasm  cytosol  cytosol  vitamin metabolic process  water-soluble vitamin metabolic process  Mo-molybdopterin cofactor biosynthetic process  Mo-molybdopterin cofactor biosynthetic process  molybdopterin synthase complex  molybdopterin synthase complex  molybdopterin synthase activity  molybdopterin synthase activity  molybdopterin synthase activity  molybdopterin cofactor biosynthetic process  identical protein binding  small molecule metabolic process  extracellular exosome  
Pathways : KEGGFolate biosynthesis    Sulfur relay system   
NDEx NetworkMOCS2
Atlas of Cancer Signalling NetworkMOCS2
Wikipedia pathwaysMOCS2
Orthology - Evolution
OrthoDB4338
GeneTree (enSembl)ENSG00000164172
Phylogenetic Trees/Animal Genes : TreeFamMOCS2
HOVERGENO96033
HOGENOMO96033
Homologs : HomoloGeneMOCS2
Homology/Alignments : Family Browser (UCSC)MOCS2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMOCS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MOCS2
dbVarMOCS2
ClinVarMOCS2
1000_GenomesMOCS2 
Exome Variant ServerMOCS2
ExAC (Exome Aggregation Consortium)MOCS2 (select the gene name)
Genetic variants : HAPMAP4338
Genomic Variants (DGV)MOCS2 [DGVbeta]
DECIPHER (Syndromes)5:52391509-52405602  ENSG00000164172
CONAN: Copy Number AnalysisMOCS2 
Mutations
ICGC Data PortalMOCS2 
TCGA Data PortalMOCS2 
Broad Tumor PortalMOCS2
OASIS PortalMOCS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMOCS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMOCS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MOCS2
DgiDB (Drug Gene Interaction Database)MOCS2
DoCM (Curated mutations)MOCS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MOCS2 (select a term)
intoGenMOCS2
Cancer3DMOCS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM252160    603708   
Orphanet21307   
MedgenMOCS2
Genetic Testing Registry MOCS2
NextProtO96033 [Medical]
TSGene4338
GENETestsMOCS2
Huge Navigator MOCS2 [HugePedia]
snp3D : Map Gene to Disease4338
BioCentury BCIQMOCS2
ClinGenMOCS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4338
Chemical/Pharm GKB GenePA30903
Clinical trialMOCS2
Miscellaneous
canSAR (ICR)MOCS2 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMOCS2
EVEXMOCS2
GoPubMedMOCS2
iHOPMOCS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:33:24 CET 2017

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