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MOK (MOK protein kinase)

Identity

Alias_namesRAGE
renal tumor antigen
Alias_symbol (synonym)RAGE1
STK30
Other aliasRAGE-1
HGNC (Hugo) MOK
LocusID (NCBI) 5891
Atlas_Id 42034
Location 14q32.31  [Link to chromosome band 14q32]
Location_base_pair Starts at 102695158 and ends at 102771537 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MOK (14q32.31) / MOK (14q32.31)MOK (14q32.31) / TFCP2L1 (2q14.2)SLC2A4RG (20q13.33) / MOK (14q32.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MOK   9833
Cards
Entrez_Gene (NCBI)MOK  5891  MOK protein kinase
AliasesRAGE; RAGE-1; RAGE1; STK30
GeneCards (Weizmann)MOK
Ensembl hg19 (Hinxton)ENSG00000080823 [Gene_View]  chr14:102695158-102771537 [Contig_View]  MOK [Vega]
Ensembl hg38 (Hinxton)ENSG00000080823 [Gene_View]  chr14:102695158-102771537 [Contig_View]  MOK [Vega]
ICGC DataPortalENSG00000080823
TCGA cBioPortalMOK
AceView (NCBI)MOK
Genatlas (Paris)MOK
WikiGenes5891
SOURCE (Princeton)MOK
Genetics Home Reference (NIH)MOK
Genomic and cartography
GoldenPath hg19 (UCSC)MOK  -     chr14:102695158-102771537 -  14q32.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MOK  -     14q32.31   [Description]    (hg38-Dec_2013)
EnsemblMOK - 14q32.31 [CytoView hg19]  MOK - 14q32.31 [CytoView hg38]
Mapping of homologs : NCBIMOK [Mapview hg19]  MOK [Mapview hg38]
OMIM605762   
Gene and transcription
Genbank (Entrez)AB022694 AK094003 AK094747 AK131542 AK302349
RefSeq transcript (Entrez)NM_001272011 NM_014226
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)MOK
Cluster EST : UnigeneHs.104119 [ NCBI ]
CGAP (NCI)Hs.104119
Alternative Splicing GalleryENSG00000080823
Gene ExpressionMOK [ NCBI-GEO ]   MOK [ EBI - ARRAY_EXPRESS ]   MOK [ SEEK ]   MOK [ MEM ]
Gene Expression Viewer (FireBrowse)MOK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5891
GTEX Portal (Tissue expression)MOK
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UQ07   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UQ07  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UQ07
Splice isoforms : SwissVarQ9UQ07
Catalytic activity : Enzyme2.7.11.22 [ Enzyme-Expasy ]   2.7.11.222.7.11.22 [ IntEnz-EBI ]   2.7.11.22 [ BRENDA ]   2.7.11.22 [ KEGG ]   
PhosPhoSitePlusQ9UQ07
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)MOK
DMDM Disease mutations5891
Blocks (Seattle)MOK
SuperfamilyQ9UQ07
Human Protein AtlasENSG00000080823
Peptide AtlasQ9UQ07
HPRD09310
IPIIPI00413657   IPI00472352   IPI00398649   IPI00974433   IPI00980194   IPI00974308   IPI00977893   IPI00398648   IPI00973746   IPI00980025   IPI00973783   IPI00985280   
Protein Interaction databases
DIP (DOE-UCLA)Q9UQ07
IntAct (EBI)Q9UQ07
FunCoupENSG00000080823
BioGRIDMOK
STRING (EMBL)MOK
ZODIACMOK
Ontologies - Pathways
QuickGOQ9UQ07
Ontology : AmiGOprotein kinase activity  protein serine/threonine kinase activity  cyclin-dependent protein serine/threonine kinase activity  ATP binding  cytoplasm  protein phosphorylation  signal transduction  regulation of cell cycle  
Ontology : EGO-EBIprotein kinase activity  protein serine/threonine kinase activity  cyclin-dependent protein serine/threonine kinase activity  ATP binding  cytoplasm  protein phosphorylation  signal transduction  regulation of cell cycle  
NDEx NetworkMOK
Atlas of Cancer Signalling NetworkMOK
Wikipedia pathwaysMOK
Orthology - Evolution
OrthoDB5891
GeneTree (enSembl)ENSG00000080823
Phylogenetic Trees/Animal Genes : TreeFamMOK
HOVERGENQ9UQ07
HOGENOMQ9UQ07
Homologs : HomoloGeneMOK
Homology/Alignments : Family Browser (UCSC)MOK
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMOK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MOK
dbVarMOK
ClinVarMOK
1000_GenomesMOK 
Exome Variant ServerMOK
ExAC (Exome Aggregation Consortium)MOK (select the gene name)
Genetic variants : HAPMAP5891
Genomic Variants (DGV)MOK [DGVbeta]
DECIPHER (Syndromes)14:102695158-102771537  ENSG00000080823
CONAN: Copy Number AnalysisMOK 
Mutations
ICGC Data PortalMOK 
TCGA Data PortalMOK 
Broad Tumor PortalMOK
OASIS PortalMOK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMOK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMOK
BioMutasearch MOK
DgiDB (Drug Gene Interaction Database)MOK
DoCM (Curated mutations)MOK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MOK (select a term)
intoGenMOK
Cancer3DMOK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605762   
Orphanet
MedgenMOK
Genetic Testing Registry MOK
NextProtQ9UQ07 [Medical]
TSGene5891
GENETestsMOK
Huge Navigator MOK [HugePedia]
snp3D : Map Gene to Disease5891
BioCentury BCIQMOK
ClinGenMOK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5891
Chemical/Pharm GKB GenePA34187
Clinical trialMOK
Miscellaneous
canSAR (ICR)MOK (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMOK
EVEXMOK
GoPubMedMOK
iHOPMOK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:17:14 CET 2017

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