MON1B (MON1 homolog B, secretory trafficking associated)

2014-11-01  

Identity

HGNC
MON1B
LOCATION
16q23.1
LOCUSID
22879
ALIAS
HSRG1,SAND2,SRG1

Other Information

Locus ID:

NCBI: 22879
MIM: 608954
HGNC: 25020
Ensembl: ENSG00000103111

Variants:

dbSNP: 22879
ClinVar: 22879
TCGA: ENSG00000103111
COSMIC: MON1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000103111ENST00000248248Q7L1V2
ENSG00000103111ENST00000439557E7EW32
ENSG00000103111ENST00000545553Q7L1V2
ENSG00000103111ENST00000563279H3BU99
ENSG00000103111ENST00000563612H3BPL8
ENSG00000103111ENST00000564006H3BQ73
ENSG00000103111ENST00000567291H3BUX9
ENSG00000103111ENST00000569610H3BR21

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.11
198442552010Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.9
269874022016Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b.5
198512962010Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.3
128283402003Identification of a novel human sand family protein in human fibroblasts induced by herpes simplex virus 1 binding.1
171096352006Protein encoded by HSV-1 stimulation-related gene 1 (HSRG1) interacts with and inhibits SV40 large T antigen.1

Citation

Dessen P

MON1B (MON1 homolog B, secretory trafficking associated)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70369/mon1b