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MORC2 (MORC family CW-type zinc finger 2)

Identity

Alias_namesZCWCC1
zinc finger, CW-type with coiled-coil domain 1
zinc finger, CW type with coiled-coil domain 1
Alias_symbol (synonym)ZCW3
KIAA0852
AC004542.C22.1
Other aliasCMT2Z
HGNC (Hugo) MORC2
LocusID (NCBI) 22880
Atlas_Id 52474
Location 22q12.2  [Link to chromosome band 22q12]
Location_base_pair Starts at 30925130 and ends at 30968287 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MORC2   23573
Cards
Entrez_Gene (NCBI)MORC2  22880  MORC family CW-type zinc finger 2
AliasesCMT2Z; ZCW3; ZCWCC1
GeneCards (Weizmann)MORC2
Ensembl hg19 (Hinxton)ENSG00000133422 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000133422 [Gene_View]  chr22:30925130-30968287 [Contig_View]  MORC2 [Vega]
ICGC DataPortalENSG00000133422
TCGA cBioPortalMORC2
AceView (NCBI)MORC2
Genatlas (Paris)MORC2
WikiGenes22880
SOURCE (Princeton)MORC2
Genetics Home Reference (NIH)MORC2
Genomic and cartography
GoldenPath hg38 (UCSC)MORC2  -     chr22:30925130-30968287 -  22q12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MORC2  -     22q12.2   [Description]    (hg19-Feb_2009)
EnsemblMORC2 - 22q12.2 [CytoView hg19]  MORC2 - 22q12.2 [CytoView hg38]
Mapping of homologs : NCBIMORC2 [Mapview hg19]  MORC2 [Mapview hg38]
OMIM616661   616688   
Gene and transcription
Genbank (Entrez)AB020659 AL133637 BC019257 BC136782 BC141657
RefSeq transcript (Entrez)NM_001303256 NM_001303257 NM_014941
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MORC2
Cluster EST : UnigeneHs.707161 [ NCBI ]
CGAP (NCI)Hs.707161
Alternative Splicing GalleryENSG00000133422
Gene ExpressionMORC2 [ NCBI-GEO ]   MORC2 [ EBI - ARRAY_EXPRESS ]   MORC2 [ SEEK ]   MORC2 [ MEM ]
Gene Expression Viewer (FireBrowse)MORC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22880
GTEX Portal (Tissue expression)MORC2
Human Protein AtlasENSG00000133422-MORC2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6X9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6X9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6X9
Splice isoforms : SwissVarQ9Y6X9
PhosPhoSitePlusQ9Y6X9
Domaine pattern : Prosite (Expaxy)ZF_CW (PS51050)   
Domains : Interpro (EBI)HATPase_C    Znf_CW   
Domain families : Pfam (Sanger)zf-CW (PF07496)   
Domain families : Pfam (NCBI)pfam07496   
Conserved Domain (NCBI)MORC2
DMDM Disease mutations22880
Blocks (Seattle)MORC2
SuperfamilyQ9Y6X9
Human Protein Atlas [tissue]ENSG00000133422-MORC2 [tissue]
Peptide AtlasQ9Y6X9
HPRD11699
IPIIPI00455518   IPI00873776   IPI00892877   IPI00894300   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6X9
IntAct (EBI)Q9Y6X9
FunCoupENSG00000133422
BioGRIDMORC2
STRING (EMBL)MORC2
ZODIACMORC2
Ontologies - Pathways
QuickGOQ9Y6X9
Ontology : AmiGOnucleus  nucleus  cytosol  fatty acid metabolic process  zinc ion binding  
Ontology : EGO-EBInucleus  nucleus  cytosol  fatty acid metabolic process  zinc ion binding  
NDEx NetworkMORC2
Atlas of Cancer Signalling NetworkMORC2
Wikipedia pathwaysMORC2
Orthology - Evolution
OrthoDB22880
GeneTree (enSembl)ENSG00000133422
Phylogenetic Trees/Animal Genes : TreeFamMORC2
HOVERGENQ9Y6X9
HOGENOMQ9Y6X9
Homologs : HomoloGeneMORC2
Homology/Alignments : Family Browser (UCSC)MORC2
Gene fusions - Rearrangements
Fusion: Tumor Portal MORC2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMORC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MORC2
dbVarMORC2
ClinVarMORC2
1000_GenomesMORC2 
Exome Variant ServerMORC2
ExAC (Exome Aggregation Consortium)ENSG00000133422
GNOMAD BrowserENSG00000133422
Genetic variants : HAPMAP22880
Genomic Variants (DGV)MORC2 [DGVbeta]
DECIPHERMORC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMORC2 
Mutations
ICGC Data PortalMORC2 
TCGA Data PortalMORC2 
Broad Tumor PortalMORC2
OASIS PortalMORC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMORC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMORC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MORC2
DgiDB (Drug Gene Interaction Database)MORC2
DoCM (Curated mutations)MORC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MORC2 (select a term)
intoGenMORC2
Cancer3DMORC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616661    616688   
Orphanet
MedgenMORC2
Genetic Testing Registry MORC2
NextProtQ9Y6X9 [Medical]
TSGene22880
GENETestsMORC2
Target ValidationMORC2
Huge Navigator MORC2 [HugePedia]
snp3D : Map Gene to Disease22880
BioCentury BCIQMORC2
ClinGenMORC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22880
Chemical/Pharm GKB GenePA134986990
Clinical trialMORC2
Miscellaneous
canSAR (ICR)MORC2 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMORC2
EVEXMORC2
GoPubMedMORC2
iHOPMORC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 13:01:07 CET 2017

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