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MORF4L1 (mortality factor 4 like 1)

Identity

Alias_symbol (synonym)MRG15
MORFRG15
HsT17725
Eaf3
MEAF3
Other aliasFWP006
S863-6
HGNC (Hugo) MORF4L1
LocusID (NCBI) 10933
Atlas_Id 50247
Location 15q25.1  [Link to chromosome band 15q25]
Location_base_pair Starts at 78872781 and ends at 78897739 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AD_1 () / MORF4L1 (15q25.1)MORF4L1 (15q25.1) / RAB21 (12q21.1)TYMS (18p11.32) / MORF4L1 (15q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MORF4L1   16989
Cards
Entrez_Gene (NCBI)MORF4L1  10933  mortality factor 4 like 1
AliasesEaf3; FWP006; HsT17725; MEAF3; 
MORFRG15; MRG15; S863-6
GeneCards (Weizmann)MORF4L1
Ensembl hg19 (Hinxton)ENSG00000185787 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185787 [Gene_View]  chr15:78872781-78897739 [Contig_View]  MORF4L1 [Vega]
ICGC DataPortalENSG00000185787
TCGA cBioPortalMORF4L1
AceView (NCBI)MORF4L1
Genatlas (Paris)MORF4L1
WikiGenes10933
SOURCE (Princeton)MORF4L1
Genetics Home Reference (NIH)MORF4L1
Genomic and cartography
GoldenPath hg38 (UCSC)MORF4L1  -     chr15:78872781-78897739 +  15q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MORF4L1  -     15q25.1   [Description]    (hg19-Feb_2009)
EnsemblMORF4L1 - 15q25.1 [CytoView hg19]  MORF4L1 - 15q25.1 [CytoView hg38]
Mapping of homologs : NCBIMORF4L1 [Mapview hg19]  MORF4L1 [Mapview hg38]
OMIM607303   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001265603 NM_001265604 NM_001265605 NM_006791 NM_206839
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MORF4L1
Cluster EST : UnigeneHs.374503 [ NCBI ]
CGAP (NCI)Hs.374503
Alternative Splicing GalleryENSG00000185787
Gene ExpressionMORF4L1 [ NCBI-GEO ]   MORF4L1 [ EBI - ARRAY_EXPRESS ]   MORF4L1 [ SEEK ]   MORF4L1 [ MEM ]
Gene Expression Viewer (FireBrowse)MORF4L1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10933
GTEX Portal (Tissue expression)MORF4L1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBU8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UBU8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBU8
Splice isoforms : SwissVarQ9UBU8
PhosPhoSitePlusQ9UBU8
Domaine pattern : Prosite (Expaxy)MRG (PS51640)   
Domains : Interpro (EBI)Chromodomain-like    MRG    MRG_dom    Tudor-knot   
Domain families : Pfam (Sanger)MRG (PF05712)    Tudor-knot (PF11717)   
Domain families : Pfam (NCBI)pfam05712    pfam11717   
Conserved Domain (NCBI)MORF4L1
DMDM Disease mutations10933
Blocks (Seattle)MORF4L1
PDB (SRS)2AQL    2EFI    2F5J    2F5K    2LKM    2N1D   
PDB (PDBSum)2AQL    2EFI    2F5J    2F5K    2LKM    2N1D   
PDB (IMB)2AQL    2EFI    2F5J    2F5K    2LKM    2N1D   
PDB (RSDB)2AQL    2EFI    2F5J    2F5K    2LKM    2N1D   
Structural Biology KnowledgeBase2AQL    2EFI    2F5J    2F5K    2LKM    2N1D   
SCOP (Structural Classification of Proteins)2AQL    2EFI    2F5J    2F5K    2LKM    2N1D   
CATH (Classification of proteins structures)2AQL    2EFI    2F5J    2F5K    2LKM    2N1D   
SuperfamilyQ9UBU8
Human Protein AtlasENSG00000185787
Peptide AtlasQ9UBU8
HPRD09532
IPIIPI00409675   IPI00930346   IPI00550968   
Protein Interaction databases
DIP (DOE-UCLA)Q9UBU8
IntAct (EBI)Q9UBU8
FunCoupENSG00000185787
BioGRIDMORF4L1
STRING (EMBL)MORF4L1
ZODIACMORF4L1
Ontologies - Pathways
QuickGOQ9UBU8
Ontology : AmiGOdouble-strand break repair via homologous recombination  chromatin binding  protein binding  nucleoplasm  chromatin remodeling  chromatin silencing  transcription, DNA-templated  cell proliferation  histone deacetylation  Sin3 complex  nuclear speck  NuA4 histone acetyltransferase complex  regulation of growth  histone H4 acetylation  histone H2A acetylation  protein N-terminus binding  
Ontology : EGO-EBIdouble-strand break repair via homologous recombination  chromatin binding  protein binding  nucleoplasm  chromatin remodeling  chromatin silencing  transcription, DNA-templated  cell proliferation  histone deacetylation  Sin3 complex  nuclear speck  NuA4 histone acetyltransferase complex  regulation of growth  histone H4 acetylation  histone H2A acetylation  protein N-terminus binding  
NDEx NetworkMORF4L1
Atlas of Cancer Signalling NetworkMORF4L1
Wikipedia pathwaysMORF4L1
Orthology - Evolution
OrthoDB10933
GeneTree (enSembl)ENSG00000185787
Phylogenetic Trees/Animal Genes : TreeFamMORF4L1
HOVERGENQ9UBU8
HOGENOMQ9UBU8
Homologs : HomoloGeneMORF4L1
Homology/Alignments : Family Browser (UCSC)MORF4L1
Gene fusions - Rearrangements
Fusion Cancer (Beijing)AD_1 [MORF4L1]  -  15q25.1 [FUSC003871]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMORF4L1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MORF4L1
dbVarMORF4L1
ClinVarMORF4L1
1000_GenomesMORF4L1 
Exome Variant ServerMORF4L1
ExAC (Exome Aggregation Consortium)MORF4L1 (select the gene name)
Genetic variants : HAPMAP10933
Genomic Variants (DGV)MORF4L1 [DGVbeta]
DECIPHERMORF4L1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMORF4L1 
Mutations
ICGC Data PortalMORF4L1 
TCGA Data PortalMORF4L1 
Broad Tumor PortalMORF4L1
OASIS PortalMORF4L1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMORF4L1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMORF4L1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MORF4L1
DgiDB (Drug Gene Interaction Database)MORF4L1
DoCM (Curated mutations)MORF4L1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MORF4L1 (select a term)
intoGenMORF4L1
Cancer3DMORF4L1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607303   
Orphanet
MedgenMORF4L1
Genetic Testing Registry MORF4L1
NextProtQ9UBU8 [Medical]
TSGene10933
GENETestsMORF4L1
Target ValidationMORF4L1
Huge Navigator MORF4L1 [HugePedia]
snp3D : Map Gene to Disease10933
BioCentury BCIQMORF4L1
ClinGenMORF4L1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10933
Chemical/Pharm GKB GenePA134895182
Clinical trialMORF4L1
Miscellaneous
canSAR (ICR)MORF4L1 (select the gene name)
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMORF4L1
EVEXMORF4L1
GoPubMedMORF4L1
iHOPMORF4L1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:20:26 CEST 2017

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